公开(公告)号：US10400249B2

公开(公告)日：2019-09-03

申请号：US15124861

申请日：2015-03-09

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT ,  BAYER CROPSCIENCE LP

Inventor： Fabien Poree ,  Bernd Laber ,  Gudrun Lange ,  Manuel Dubald ,  Roxanne Armstrong

IPC: C12N15/82 ,  A01N43/713 ,  C12N9/02

Abstract: In the present invention, HPPD enzymes and plants containing them showing a full tolerance against several classes of HPPD-inhibitors are described.A set of HPPD enzymes have been designed which have either no or only a significantly reduced affinity to HPPD inhibitors and, at the same time, the rate of dissociation of the HPPD inhibitors of the enzyme is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors.In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

公开(公告)号：US10793872B2

公开(公告)日：2020-10-06

申请号：US14441638

申请日：2013-09-13

Applicant: Bayer CropScience AG ,  Bayer Cropscience LP

Inventor： Fabien Poree ,  Volker Heinrichs ,  Gudrun Lange ,  Bernd Laber ,  Cheryl Peters ,  Laura Schouten

IPC: C12N15/82 ,  C12N9/02

Abstract: Compositions and methods for conferring herbicide tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

公开(公告)号：US10159249B2

公开(公告)日：2018-12-25

申请号：US15036690

申请日：2014-11-25

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Fabien Poree ,  Christian Waldraff ,  Bernd Laber ,  Arnim Koehn ,  Elmar Gatzweiler ,  Klaus Trabold

IPC: A01N43/713 ,  A01N43/68 ,  A01N43/707 ,  A01N57/20 ,  A01N25/00 ,  A01N43/70

Abstract: The use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides by containing one or more chimeric gene(s) comprising (I) a DNA sequence encoding hydroxyphenylpyruvate dioxygenase (HPPD) derived from a member of a group of organisms consisting of (a) Avena, (b) Pseudomonas, (c) Synechococcoideae, (d) Blepharismidae, (e) Rhodococcus, (f) Picrophilaceae, (g) Kordia, or (II) one or more mutated DNA sequences of HPPD encoding genes of the before defined organisms, preferably from Pseudomonas, or (III) one or more DNA sequences encoding mutated maize (Zea mays) or soybean (Glycine max) HPPD each being mutated as described in WO 2012/021785.

公开(公告)号：US20150267180A1

公开(公告)日：2015-09-24

申请号：US14441638

申请日：2013-09-13

Applicant: BAYER CROPSCIENCE LP ,  BAYER CROPSCIENCE AG

Inventor： Fabien Poree ,  Volker Heinrichs ,  Gudrun Lange ,  Bernd Laber ,  Cheryl Peters ,  Laura Schouten

IPC: C12N9/02 ,  A01N43/647 ,  A01N43/82 ,  C12N15/82 ,  A01N43/80 ,  A01N43/40 ,  A01N43/56 ,  A01N43/713 ,  A01N35/06

Abstract: Compositions and methods for conferring herbicide tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

Abstract translation: 提供了赋予对细菌，植物，植物细胞，组织和种子的除草剂耐受性的组合物和方法。 组合物包括编码除草剂耐受性多肽的多核苷酸，包含那些多核苷酸的载体和包含载体的宿主细胞。 本发明的核苷酸序列可用于DNA构建体或表达盒中用于在生物体（包括微生物和植物）中转化和表达。 组合物还包括转化的细菌，植物，植物细胞，组织和种子。 特别地，提供了编码HPPD抑制剂耐受多肽的分离的多核苷酸。 另外，包括对应于多核苷酸的氨基酸序列。