公开(公告)号：US09340526B2

公开(公告)日：2016-05-17

申请号：US14665583

申请日：2015-03-23

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii Pazenok ,  Norbert Lui ,  Harry Blaschke

IPC: C07D401/04

CPC classification number: C07D401/04 ,  Y02P20/55

Abstract: The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof.

公开(公告)号：US09969717B2

公开(公告)日：2018-05-15

申请号：US15493087

申请日：2017-04-20

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07D401/00 ,  C07D401/14

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

公开(公告)号：US09695126B2

公开(公告)日：2017-07-04

申请号：US15188164

申请日：2016-06-21

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Guenter Bartels ,  Angela Becker ,  Juergen Benting ,  Christoph-Andreas Braun ,  Peter Dahmen ,  Philippe Desbordes ,  Christophe Dubost ,  Stephanie Gary ,  Ulrich Gorgens ,  Hiroyuki Hadano ,  Benoit Hartmann ,  Thomas Knobloch ,  Marc Kosten ,  Norbert Lui ,  Ruth Meissner ,  Sergiy Pazenok ,  Rachel Rama ,  Arnd Voerste ,  Ulrike Wachendorff-Neumann

IPC: C07D231/16 ,  C07D401/12 ,  A01N55/00 ,  A01N43/56 ,  C07F7/08

CPC classification number: C07D231/16 ,  A01N43/56 ,  A01N55/00 ,  C07D401/12 ,  C07F7/0812

Abstract: The present invention relates to pyrazole carboxamides derivatives of formula (1) wherein Y represents CR5 or N, T represents S or O, X1 and X2 represent a chlorine or a fluorine atom, and Z1 represents a substituted or non-substituted cyclopropyl; Their process of preparation, their use as fungicide, and/or anti-mycotoxin active agents, and/or insecticide, and/or nematicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.

公开(公告)号：US09670182B2

公开(公告)日：2017-06-06

申请号：US14924889

申请日：2015-10-28

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07D401/00 ,  C07D401/14 ,  C07C255/60 ,  C07C253/30

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

公开(公告)号：US09398767B2

公开(公告)日：2016-07-26

申请号：US14166773

申请日：2014-01-28

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Guenter Bartels ,  Angela Becker ,  Juergen Benting ,  Christoph-Andreas Braun ,  Peter Dahmen ,  Philippe Desbordes ,  Christophe Dubost ,  Stephanie Gary ,  Ulrich Gorgens ,  Hiroyuki Hadano ,  Benoit Hartmann ,  Thomas Knobloch ,  Marc Kosten ,  Norbert Lui ,  Ruth Meissner ,  Sergiy Pazenok ,  Rachel Rama ,  Arnd Voerste ,  Ulrike Wachendorff-Neumann

IPC: A01N43/56 ,  C07D401/12 ,  C07D231/16 ,  A01N55/00 ,  C07F7/08

CPC classification number: C07D231/16 ,  A01N43/56 ,  A01N55/00 ,  C07D401/12 ,  C07F7/0812

Abstract: The present invention relates to pyrazole carboxamides derivatives of formula (1) wherein Y represents CR5 or N, T represents S or O, X1 and X2 represent a chlorine or a fluorine atom, and Z1 represents a substituted or non-substituted cyclopropyl; Their process of preparation, their use as fungicide, and/or anti-mycotoxin active agents, and/or insecticide, and/or nematicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.

Abstract translation: 本发明涉及式（1）的吡唑甲酰胺衍生物，其中Y表示CR5或N，T表示S或O，X1和X2表示氯或氟原子，Z1表示取代或未取代的环丙基; 其制备方法，它们作为杀真菌剂的用途和/或抗真菌毒素活性剂，和/或杀虫剂和/或杀线虫剂，特别是杀真菌剂组合物的形式，以及用于控制植物病原真菌，特别是植物的方法， 使用这些化合物或组合物。

公开(公告)号：US20150191447A1

公开(公告)日：2015-07-09

申请号：US14665583

申请日：2015-03-23

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii PAZENOK ,  Norbert Lui ,  Harry Blaschke

IPC: C07D401/04

CPC classification number: C07D401/04 ,  Y02P20/55

Abstract: The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof.

Abstract translation: 本发明涉及一种制备1-吡啶基取代的吡唑的方法，其中包括乙酰基酮与吡啶基肼衍生物的反应，得到1-吡啶基取代的二氢-1H-吡唑，进一步反应，除去水，得到1-吡啶基 - 取代的三卤代甲基吡唑，以及其进一步处理。

公开(公告)号：US20150011772A1

公开(公告)日：2015-01-08

申请号：US14375496

申请日：2013-02-06

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07C253/30 ,  C07D401/14 ,  C07C255/60

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

Abstract translation: 本发明涉及一种制备式（I）的取代的邻氨基苯甲酸衍生物的方法，其中R 1，R 2，R 3和R 4各自如说明书中所定义，通过在存在下转化通式（Ⅳ）的化合物 的钯催化剂和一氧化碳。 本发明同样涉及通式（IV）的化合物。

公开(公告)号：US20140330051A1

公开(公告)日：2014-11-06

申请号：US14350838

申请日：2012-10-11

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Norbert Lui ,  Shanthan Rao Pamulaparthy ,  Srinivas Pvss ,  Thomas Vijaya ,  Sridhar Madabhushi ,  Rambabu Yadla ,  Narsaiah Banda ,  Sergii Pazenok

IPC: C07C17/35 ,  B01J27/138 ,  B01J23/86 ,  C07C17/21

CPC classification number: C07C17/35 ,  B01J21/18 ,  B01J23/06 ,  B01J23/862 ,  B01J23/866 ,  B01J27/138 ,  B01J37/0201 ,  B01J37/26 ,  C07C17/206 ,  C07C17/21 ,  Y02P20/582 ,  C07C19/12

Abstract: The invention is directed to a catalyst for the gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene with HF to give 1-chloro-2,2-difluoroethane which catalyst is prepared by co-depositing FeCl3 and MgCl2 on chromia-alumina, or co-depositing Cr(NO3)3 and Ni(NO3)2 on active carbon, or by doping alumina with ZnCl2, and to a process for the preparation of 1-chloro-2,2-difluoroethane comprising a catalytic gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene wherein one of the catalysts according to claim 2 or 3 is used.

Abstract translation: 本发明涉及用于将HF与1,1,1-三氯乙烷和/或1,2-二氯乙烯气相氟化的催化剂，得到1-氯-2,2-二氟乙烷，该催化剂通过共沉积FeCl 3 和氧化铬 - 氧化铝上的MgCl 2或在活性炭上共沉淀Cr（NO 3）3和Ni（NO 3）2，或通过用ZnCl 2掺杂氧化铝，以及制备1-氯-2,2-二氟乙烷 包括1,1,2-三氯乙烷和/或1,2-二氯乙烯的催化气相氟化，其中使用根据权利要求2或3的催化剂之一。

公开(公告)号：US08765971B2

公开(公告)日：2014-07-01

申请号：US13770720

申请日：2013-02-19

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii Pazenok ,  Norbert Lui ,  Marc Kosten ,  Guenter Bartels

IPC: C07D231/16 ,  C07D231/22 ,  C07D231/12

CPC classification number: C07D231/16

Abstract: The present invention relates to a novel process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides, a useful intermediate in the manufacture of fungicides.

Abstract translation: 本发明涉及一种制备5-氟-1-烷基-3-氟烷基-1H-吡唑-4-羰基氯的新方法，该制备杀真菌剂是有用的中间体。

公开(公告)号：US09000242B2

公开(公告)日：2015-04-07

申请号：US14350838

申请日：2012-10-11

Applicant: Bayer Intellectual Property GmbH

Inventor： Norbert Lui ,  Shanthan Rao Pamulaparthy ,  Srinivas Pvss ,  Thomas Vijaya ,  Sridhar Madabhushi ,  Rambabu Yadla ,  Narsaiah Banda ,  Sergii Pazenok

IPC: C07C17/35 ,  C07C17/21 ,  B01J27/138 ,  B01J23/86

CPC classification number: C07C17/35 ,  B01J21/18 ,  B01J23/06 ,  B01J23/862 ,  B01J23/866 ,  B01J27/138 ,  B01J37/0201 ,  B01J37/26 ,  C07C17/206 ,  C07C17/21 ,  Y02P20/582 ,  C07C19/12

Abstract: The invention is directed to a catalyst for the gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene with HF to give 1-chloro-2,2-difluoroethane which catalyst is prepared by co-depositing FeCl3 and MgCl2 on chromia-alumina, or co-depositing Cr(NO3)3 and Ni(NO3)2 on active carbon, or by doping alumina with ZnCl2, and to a process for the preparation of 1-chloro-2,2-difluoroethane comprising a catalytic gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene wherein one of the catalysts according to claim 2 or 3 is used.

Abstract translation: 本发明涉及用于将HF与1,1,1-三氯乙烷和/或1,2-二氯乙烯气相氟化的催化剂，得到1-氯-2,2-二氟乙烷，该催化剂通过共沉积FeCl 3 和氧化铬 - 氧化铝上的MgCl 2或在活性炭上共沉淀Cr（NO 3）3和Ni（NO 3）2，或通过用ZnCl 2掺杂氧化铝，以及制备1-氯-2,2-二氟乙烷 包括1,1,2-三氯乙烷和/或1,2-二氯乙烯的催化气相氟化，其中使用根据权利要求2或3的催化剂之一。