公开(公告)号：US09096535B2

公开(公告)日：2015-08-04

申请号：US14378372

申请日：2013-02-13

Applicant: BAYER INTELLECTUAL PROPERTY GMBH ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Sergii Pazenok ,  Bernard Langlois ,  Thierry Billard ,  Julien Barbion ,  Olivier Marrec ,  Jean-Pierre Vors

IPC: C07D231/18 ,  C07D405/04 ,  C07C221/00 ,  C07C225/16

CPC classification number: C07D231/18 ,  C07C221/00 ,  C07C225/16 ,  C07D405/04

Abstract: The present invention pertains to novel enaminoketones containing a CF3O-group, novel pyrazole-derivatives containing a CF3O group as well as to a novel process for their preparation comprising aminoformylation of CF3O-ketones and cyclization of the obtained CF3O-enaminoketones with hydrazines to trifluoromethoxy pyrazoles.

Abstract translation: 本发明涉及含有CF 3 O-基团的新型烯胺酮，含有CF 3 O基团的新型吡唑衍生物及其制备方法，其包括CF 3 O-酮的氨基甲酰化和所得的CF 3 O-烯胺酮与肼与三氟甲氧基吡唑的环化 。

公开(公告)号：US09969717B2

公开(公告)日：2018-05-15

申请号：US15493087

申请日：2017-04-20

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07D401/00 ,  C07D401/14

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

公开(公告)号：US09670182B2

公开(公告)日：2017-06-06

申请号：US14924889

申请日：2015-10-28

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07D401/00 ,  C07D401/14 ,  C07C255/60 ,  C07C253/30

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

公开(公告)号：US09029577B2

公开(公告)日：2015-05-12

申请号：US14375816

申请日：2013-01-30

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii Pazenok ,  Albert Schnatterer

IPC: C07D317/12

CPC classification number: C07D317/12

Abstract: The present invention relates to a novel method for preparing methylene-1,3-dioxolanes of the general formula (I) in which R1 and R2 have the meanings stated in the description. Methylene-1,3-dioxolanes are important intermediates for preparing pyrazoles and anthranilic acid amides, which may be used as insecticides.

Abstract translation: 本发明涉及一种制备通式（I）的亚甲基-1,3-二氧戊环的新方法，其中R1和R2具有说明书中所述的含义。 亚甲基-1,3-二氧戊环是制备可用作杀虫剂的吡唑和邻氨基苯甲酸酰胺的重要中间体。

公开(公告)号：US20150011772A1

公开(公告)日：2015-01-08

申请号：US14375496

申请日：2013-02-06

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Thomas Himmler ,  Sergii Pazenok ,  Frank Volz ,  Norbert Lui

IPC: C07C253/30 ,  C07D401/14 ,  C07C255/60

CPC classification number: C07D401/14 ,  C07C253/30 ,  C07C255/60

Abstract: The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).

Abstract translation: 本发明涉及一种制备式（I）的取代的邻氨基苯甲酸衍生物的方法，其中R 1，R 2，R 3和R 4各自如说明书中所定义，通过在存在下转化通式（Ⅳ）的化合物 的钯催化剂和一氧化碳。 本发明同样涉及通式（IV）的化合物。

公开(公告)号：US09000242B2

公开(公告)日：2015-04-07

申请号：US14350838

申请日：2012-10-11

Applicant: Bayer Intellectual Property GmbH

Inventor： Norbert Lui ,  Shanthan Rao Pamulaparthy ,  Srinivas Pvss ,  Thomas Vijaya ,  Sridhar Madabhushi ,  Rambabu Yadla ,  Narsaiah Banda ,  Sergii Pazenok

IPC: C07C17/35 ,  C07C17/21 ,  B01J27/138 ,  B01J23/86

CPC classification number: C07C17/35 ,  B01J21/18 ,  B01J23/06 ,  B01J23/862 ,  B01J23/866 ,  B01J27/138 ,  B01J37/0201 ,  B01J37/26 ,  C07C17/206 ,  C07C17/21 ,  Y02P20/582 ,  C07C19/12

Abstract: The invention is directed to a catalyst for the gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene with HF to give 1-chloro-2,2-difluoroethane which catalyst is prepared by co-depositing FeCl3 and MgCl2 on chromia-alumina, or co-depositing Cr(NO3)3 and Ni(NO3)2 on active carbon, or by doping alumina with ZnCl2, and to a process for the preparation of 1-chloro-2,2-difluoroethane comprising a catalytic gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene wherein one of the catalysts according to claim 2 or 3 is used.

Abstract translation: 本发明涉及用于将HF与1,1,1-三氯乙烷和/或1,2-二氯乙烯气相氟化的催化剂，得到1-氯-2,2-二氟乙烷，该催化剂通过共沉积FeCl 3 和氧化铬 - 氧化铝上的MgCl 2或在活性炭上共沉淀Cr（NO 3）3和Ni（NO 3）2，或通过用ZnCl 2掺杂氧化铝，以及制备1-氯-2,2-二氟乙烷 包括1,1,2-三氯乙烷和/或1,2-二氯乙烯的催化气相氟化，其中使用根据权利要求2或3的催化剂之一。

公开(公告)号：US09340526B2

公开(公告)日：2016-05-17

申请号：US14665583

申请日：2015-03-23

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii Pazenok ,  Norbert Lui ,  Harry Blaschke

IPC: C07D401/04

CPC classification number: C07D401/04 ,  Y02P20/55

Abstract: The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof.

公开(公告)号：US20140378690A1

公开(公告)日：2014-12-25

申请号：US14375816

申请日：2013-01-30

Applicant: Bayer Intellectual Property GMBH

Inventor： Sergii Pazenok ,  Albert Schnatterer

IPC: C07D317/12

CPC classification number: C07D317/12

Abstract: The present invention relates to a novel method for preparing methylene-1,3-dioxolanes of the general formula (1) in which R1 and R2 have the meanings stated in the description. Methylene-1,3-dioxolanes are important intermediates for preparing pyrazoles and anthranilic acid amides, which may be used as insecticides.

Abstract translation: 本发明涉及一种制备通式（1）的亚甲基-1,3-二氧戊烷的新方法，其中R1和R2具有说明书中所述的含义。 亚甲基-1,3-二氧戊环是制备可用作杀虫剂的吡唑和邻氨基苯甲酸酰胺的重要中间体。

公开(公告)号：US20140330051A1

公开(公告)日：2014-11-06

申请号：US14350838

申请日：2012-10-11

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Norbert Lui ,  Shanthan Rao Pamulaparthy ,  Srinivas Pvss ,  Thomas Vijaya ,  Sridhar Madabhushi ,  Rambabu Yadla ,  Narsaiah Banda ,  Sergii Pazenok

IPC: C07C17/35 ,  B01J27/138 ,  B01J23/86 ,  C07C17/21

CPC classification number: C07C17/35 ,  B01J21/18 ,  B01J23/06 ,  B01J23/862 ,  B01J23/866 ,  B01J27/138 ,  B01J37/0201 ,  B01J37/26 ,  C07C17/206 ,  C07C17/21 ,  Y02P20/582 ,  C07C19/12

Abstract: The invention is directed to a catalyst for the gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene with HF to give 1-chloro-2,2-difluoroethane which catalyst is prepared by co-depositing FeCl3 and MgCl2 on chromia-alumina, or co-depositing Cr(NO3)3 and Ni(NO3)2 on active carbon, or by doping alumina with ZnCl2, and to a process for the preparation of 1-chloro-2,2-difluoroethane comprising a catalytic gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene wherein one of the catalysts according to claim 2 or 3 is used.

Abstract translation: 本发明涉及用于将HF与1,1,1-三氯乙烷和/或1,2-二氯乙烯气相氟化的催化剂，得到1-氯-2,2-二氟乙烷，该催化剂通过共沉积FeCl 3 和氧化铬 - 氧化铝上的MgCl 2或在活性炭上共沉淀Cr（NO 3）3和Ni（NO 3）2，或通过用ZnCl 2掺杂氧化铝，以及制备1-氯-2,2-二氟乙烷 包括1,1,2-三氯乙烷和/或1,2-二氯乙烯的催化气相氟化，其中使用根据权利要求2或3的催化剂之一。

公开(公告)号：US08765971B2

公开(公告)日：2014-07-01

申请号：US13770720

申请日：2013-02-19

Applicant: Bayer Intellectual Property GmbH

Inventor： Sergii Pazenok ,  Norbert Lui ,  Marc Kosten ,  Guenter Bartels

IPC: C07D231/16 ,  C07D231/22 ,  C07D231/12

CPC classification number: C07D231/16

Abstract: The present invention relates to a novel process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides, a useful intermediate in the manufacture of fungicides.

Abstract translation: 本发明涉及一种制备5-氟-1-烷基-3-氟烷基-1H-吡唑-4-羰基氯的新方法，该制备杀真菌剂是有用的中间体。