-
公开(公告)号：US20180112009A1
公开(公告)日：2018-04-26
申请号：US15691731
申请日：2017-08-30
发明人： Andreas WILMEN , Julia STRAßBURGER , Frank DITTMER , Michael STRERATH , Anja BUCHMÜLLER , Joanna GRUDZINSKA-GOEBEL , Ricarda FINNERN , Martina SCHÄFER , Christoph GERDES , Hannah JÖRIßEN , Asako ITAKURA , Philberta Y. LEUNG , Erik TUCKER
IPC分类号： C07K16/36
CPC分类号： C07K16/36 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要： The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
-
2.发明申请公开(公告)号：US20180051093A1
公开(公告)日：2018-02-22
申请号：US15691736
申请日：2017-08-30
发明人： Andreas WILMEN , Julia STRAßBURGER , Frank DITTMER , Michael STRERATH , Anja BUCHMÜLLER , Joanna GRUDZINSKA-GOEBEL , Ricarda FINNERN , Martina SCHÄFER , Christoph GERDES , Hannah JÖRIßEN , Asako ITAKURA , Philberta Y. LEUNG , Erik TUCKER
IPC分类号： C07K16/36
CPC分类号： C07K16/36 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要： The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
-
公开(公告)号：US20190284300A1
公开(公告)日：2019-09-19
申请号：US16292196
申请日：2019-03-04
发明人： Andreas WILMEN , Julia STRAßBURGER , Frank DITTMER , Michael STRERATH , Anja BUCHMÜLLER , Joanna GRUDZINSKA-GOEBEL , Ricarda FINNERN , Martina SCHÄFER , Christoph GERDES , Hannah JÖRIßEN , Asako ITAKURA , Philberta Y. LEUNG , Erik TUCKER
IPC分类号： C07K16/36
摘要： The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
-
公开(公告)号：US20180256591A1
公开(公告)日：2018-09-13
申请号：US15974536
申请日：2018-05-08
发明人： Lars WORTMANN , Ulrich LÜCKING , Julien LEFRANC , Hans BRIEM , Marcus KOPPITZ , Knut EIS , Franz VON NUSSBAUM , Benjamin BADER , Antje Margret WENGNER , Gerhard SIEMEISTER , Wilhelm BONE , Philip LIENAU , Joanna GRUDZINSKA-GOEBEL , Dieter MOOSMAYER , Uwe EBERSPÄCHER , Hans SCHICK
IPC分类号： A61K31/541 , A61K31/55 , A61K31/5377 , A61K31/5386 , C07D471/04 , A61K31/675 , A61K45/06 , C07D491/22 , C07D519/00 , C07F9/6561
摘要： The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (Ib), to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients.
-
公开(公告)号：US20170216304A1
公开(公告)日：2017-08-03
申请号：US15501079
申请日：2015-08-03
发明人： Lars WORTMANN , Ulrich LÜCKING , Julien LEFRANC , Hans BRIEM , Marcus KOPPITZ , Knut EIS , Franz VON NUSSBAUM , Benjamin BADER , Antje Margret WENGNER , Gerhard SIEMEISTER , Wilhelm BONE , Philip LIENAU , Joanna GRUDZINSKA-GOEBEL , Dieter MOOSMAYER , Uwe EBERSPÄCHER , Hans SCHICK
IPC分类号： A61K31/541 , A61K31/5386 , A61K31/5377 , C07D491/22 , C07F9/6561 , C07D471/04 , C07D519/00 , A61K31/55 , A61K31/675
CPC分类号： A61K31/541 , A61K31/5377 , A61K31/5386 , A61K31/55 , A61K31/675 , A61K45/06 , C07D471/04 , C07D491/22 , C07D519/00 , C07F9/6561
摘要： The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (Ib), to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative disease as a sole agent or in combination with other active ingredients.
-
-
-
-
搜索结果
5 条记录 (耗时 0.036 秒)
