公开(公告)号：US20250084396A1

公开(公告)日：2025-03-13

申请号：US18547925

申请日：2022-02-24

Applicant: Beckman Coulter, Inc.

Inventor： Thomas Marshall ,  Evan Farthing ,  Jeffrey J. Corpstein ,  Thomas G. Keen ,  Abraham Olson ,  Asmita Patel ,  Amy Yoder ,  Sahana Mallya ,  Joseph Dominic Olechno

IPC: C12N15/10

Abstract: According to various aspects of the instant disclosure, a rapidly-sedimenting magnetic particle can include a core or inner layer. The core or inner layer can include a ferrimagnetic material and have at least one of a maximum field strength ranging from about 20 emu/g to about 250 emu/g, and a remanence ranging from about 0 cmu/g to about 20 emu/g. The rapidly-sedimenting magnetic particle can further include a coating layer overlaying at least a portion of the core or inner layer. The particle can further include an outer coating layer overlaying at least a portion of the core coating.

公开(公告)号：US20230132614A1

公开(公告)日：2023-05-04

申请号：US17916634

申请日：2021-04-02

Applicant: Beckman Coulter, Inc.

Inventor： Jeffrey J. Corpstein ,  Evan Farthing ,  Thomas G. Keen ,  Abraham Olson ,  Andrew Horton ,  Kerry J. Weaver ,  Roger A. Wyman

IPC: B01L3/00 ,  B03C1/28 ,  B03C1/033 ,  B03C1/01

Abstract: The disclosure relates to methods and apparatus for processing fluids through the use of a magnetic assembly wherein the magnetic assembly includes at least one fluid chamber containing a fluid and magnetic particles.

公开(公告)号：US11530437B2

公开(公告)日：2022-12-20

申请号：US17150106

申请日：2021-01-15

Applicant: Beckman Coulter, Inc.

Inventor： Jeffrey J. Corpstein ,  Evan Farthing ,  Thomas G. Keen ,  Jianli Zhao ,  Asmita Patel ,  Yuandan Liu ,  Cuong N. Hoang ,  Emmet Welch

IPC: H01F1/00 ,  B82Y25/00 ,  C12Q1/6806 ,  H01F1/36 ,  B82Y30/00 ,  B82Y40/00

Abstract: A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.

公开(公告)号：US20210139953A1

公开(公告)日：2021-05-13

申请号：US17150106

申请日：2021-01-15

Applicant: Beckman Coulter, Inc.

Inventor： Jeffrey J. Corpstein ,  Evan Farthing ,  Thomas G. Keen ,  Jianli Zhao ,  Asmita Patel ,  Yuandan Liu ,  Cuong N. Hoang ,  Emmet Welch

IPC: C12Q1/6806 ,  H01F1/00 ,  H01F1/36

Abstract: A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.

公开(公告)号：US10288545B2

公开(公告)日：2019-05-14

申请号：US15039790

申请日：2014-11-26

Applicant: BECKMAN COULTER, INC.

Inventor： Richard R. Martin ,  Todd Halvorson ,  Jeffrey J. Corpstein

IPC: G01N15/14 ,  G01N35/10

Abstract: A fluidics system for a flow cytometer is disclosed. In some examples, the system includes a junction disposed between a pump and a sample probe. In some examples, the pump is a peristaltic pump. A pulse-attenuation system is also disclosed. A method for removing gaps caused by pulsations in output data is also disclosed. A fluidics system and method for processing samples in parallel is also disclosed. A fluidic system for a flow cytometer that includes an agitator for agitating a sample is also disclosed. A sheath fluid transfer system of a fluidic system for a flow cytometer is also disclosed.