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公开(公告)号：US12048479B2
公开(公告)日：2024-07-30
申请号：US17081918
申请日：2020-10-27
CPC分类号： A61B18/1492 , A61B2017/00185 , A61B2018/00077 , A61B2018/00136 , A61B2018/00178 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2018/00601 , A61B2018/00613 , A61B2018/00761 , A61B2018/1253 , A61B2018/126 , A61B2018/144 , A61B2018/1467 , A61B2218/002 , A61M2025/0079
摘要： In one embodiment, a medical system includes a catheter configured to be inserted into a body part of a living subject, and including an elongated deflectable element including a distal end, a proximal coupler connected to the distal end, an expandable assembly comprising a plurality of flexible polymer circuit strips, the flexible polymer circuit strips having respective proximal ends connected to, and disposed circumferentially around, the proximal coupler, respective ones of the flexible polymer circuit strips including respective multiple strip electrodes, respective contact arrays disposed at the respective proximal ends, and respective multiple circuit traces electrically connecting the respective multiple strip electrodes with the respective contact arrays, and a plurality of surface mountable electrodes mounted on, and bulging over respective ones of the flexible polymer circuit strips.
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公开(公告)号：US11974803B2
公开(公告)日：2024-05-07
申请号：US17068395
申请日：2020-10-12
发明人： Assaf Govari , Christopher Thomas Beeckler , Andres Claudio Altmann , Joseph Thomas Keyes , Kevin Justin Herrera
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2017/00867 , A61B2018/00029 , A61B2018/0022 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2218/002
摘要： In one embodiment, a catheter apparatus is configured to be inserted into a body part of a living subject, and including an elongated deflectable element including a distal end, an expandable basket assembly disposed at the distal end and comprising a plurality of splines and a plurality of electrodes disposed on the splines, an irrigation channel disposed in the elongated deflectable element, and an inflatable balloon disposed in the expandable basket assembly and including a plurality of irrigation holes in fluid connection with the irrigation channel.
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3.发明公开公开(公告)号：US20230147259A1
公开(公告)日：2023-05-11
申请号：US17523155
申请日：2021-11-10
发明人： Assaf Govari , Christopher Thomas Beeckler , Andres Claudio Altmann , Vadim Gliner , Joseph Thomas Keyes
CPC分类号： A61B18/1492 , A61B90/06 , A61B2018/0022
摘要： A system includes a catheter and a processor. The catheter includes an expandable distal-end assembly (EDEA) having: (i) a transmitter, which is coupled to the EDEA and is configured to transmit a first signal, and (ii) one or more receivers, which are coupled to an elastic component of the EDEA, and are configured to produce one or more respective second signals in response to receiving the first signal. The processor is configured to estimate, based on the one or more respective second signals, a force applied to the elastic component.
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公开(公告)号：US11490957B2
公开(公告)日：2022-11-08
申请号：US16435681
申请日：2019-06-10
摘要： A method for tissue assessment includes ablating tissue at a site within a body of a living subject using an invasive probe applied to the site. At a first stage in ablation of the tissue, first measurements are made of scattered light intensities from the site at a plurality of different wavelengths. At a second stage in the ablation of the tissue, subsequent to the first stage, second measurements are made of the scattered light intensities from the site at the plurality of different wavelengths. Progress of the ablation is assessed by computing different, respective measures of change in the scattered light intensities at the different wavelengths occurring between the first and second measurements, and comparing the respective measures.
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公开(公告)号：US20220192738A1
公开(公告)日：2022-06-23
申请号：US17131571
申请日：2020-12-22
IPC分类号： A61B18/14
摘要： An apparatus includes a shaft, configured for insertion into a body of a subject, an inflatable balloon disposed over the shaft, a plurality of leaf electrodes coupled to the balloon and shaped to define one or more leaf-electrode apertures, a tip electrode disposed at a distal end of the balloon, coupled to a distal end of the shaft, and shaped to define one or more tip-electrode apertures, a first fluid-delivery tube passing through the shaft and configured to deliver a fluid into the balloon via at least one shaft aperture in the shaft, such that the fluid passes through the leaf-electrode apertures, and a second fluid-delivery tube passing through the shaft and configured to deliver the fluid to the tip electrode, such that the fluid passes through the tip-electrode apertures. Other embodiments are also described.
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公开(公告)号：US20220104873A1
公开(公告)日：2022-04-07
申请号：US17065456
申请日：2020-10-07
IPC分类号： A61B18/14
摘要： An apparatus includes a shaft and a folding fan catheter. The shaft is configured for insertion through a sheath into a cavity of an organ of a patient. The folding fan catheter is fixed to a distal end of the shaft and includes (a) a resilient foldable frame, which is fixed to the distal end of the shaft and is configured to be unfolded so as to assume a fan shape, (b) one or more flexible surfaces, coupled to the frame to form a fan-shaped surface when the frame is unfolded, and (c) a plurality of electrodes that are disposed over the one or more flexible surfaces and are configured to contact tissue.
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公开(公告)号：US20220071695A1
公开(公告)日：2022-03-10
申请号：US17371000
申请日：2021-07-08
摘要： In one embodiment, a medical system includes a catheter to be inserted into a body part, and including an elongated deflectable element including a distal end, a proximal coupler connected to the distal end, an expandable assembly comprising flexible polymer circuit strips, each flexible polymer circuit strip including strip electrodes and a respective contact pad disposed thereon, the flexible polymer circuit strips having respective proximal ends connected to, and disposed circumferentially around, the proximal coupler, and surface mountable electrodes electrically connected to respective ones of the flexible polymer circuit strips, wherein each surface mountable electrode is electrically connected to the respective contact pad of a respective one of the flexible polymer circuit strips using at least one electrically conductive retainer.
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公开(公告)号：US20220071693A1
公开(公告)日：2022-03-10
申请号：US17081918
申请日：2020-10-27
IPC分类号： A61B18/14
摘要： In one embodiment, a medical system includes a catheter configured to be inserted into a body part of a living subject, and including an elongated deflectable element including a distal end, a proximal coupler connected to the distal end, an expandable assembly comprising a plurality of flexible polymer circuit strips, the flexible polymer circuit strips having respective proximal ends connected to, and disposed circumferentially around, the proximal coupler, respective ones of the flexible polymer circuit strips including respective multiple strip electrodes, respective contact arrays disposed at the respective proximal ends, and respective multiple circuit traces electrically connecting the respective multiple strip electrodes with the respective contact arrays, and a plurality of surface mountable electrodes mounted on, and bulging over respective ones of the flexible polymer circuit strips.
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公开(公告)号：US20210378734A1
公开(公告)日：2021-12-09
申请号：US16892514
申请日：2020-06-04
IPC分类号： A61B18/14
摘要： A system includes a catheter and an IRE pulse generator. The catheter includes an expandable frame fitted at a distal end thereof, the expandable frame including multiple electrodes configured to be placed in contact with a tissue in an organ of a patient, wherein a lateral distance between neighboring edges of any pair of adjacent electrodes is uniform along a longitudinal axis, and wherein the electrodes are configured to apply irreversible electroporation (IRE) pulses to tissue between pairs of the electrodes. The IRE pulse generator is configured to generate the IRE pulses.
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公开(公告)号：US11071585B2
公开(公告)日：2021-07-27
申请号：US16569608
申请日：2019-09-12
发明人： Xiangming Zhang , Nader Ghaly , Eid Adawi , Moe Habib Bishara , Kendra Anita McInnis , Assaf Govari , Christopher Thomas Beeckler , Joseph Thomas Keyes , Rowan Olund Hettel , Kevin Justin Herrera
摘要： The subject of this disclosure includes systems, devices and methods to treat a predetermined patient population for paroxysmal atrial fibrillation, the method including ablating tissue of one or more targeted pulmonary veins with one or more of a plurality of the electrodes of an independently controlled multi-electrode radiofrequency balloon catheter, the balloon catheter comprising the plurality of electrodes for radiofrequency ablation that are independently controllable; determining a predictor, based on ablation parameters of the balloon catheter, of single shot pulmonary vein isolation (PVI) success rate; and achieving, based on the predictor and step of ablating tissue, a single shot isolation PVI success rate in the isolation of all targeted pulmonary veins for the predetermined patient population.
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