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公开(公告)号：US20180194725A1
公开(公告)日：2018-07-12
申请号：US15743427
申请日：2016-07-15
Inventor： Kenneth Bayles , Rongshi Li , Yan Liu
IPC: C07D207/34 , C07D207/333 , C07D231/16 , C07D233/90 , C07D233/68 , C07D249/12 , A61P31/04 , A61P35/00
CPC classification number: C07D207/34 , A61P31/04 , A61P35/00 , C07D207/333 , C07D231/16 , C07D233/64 , C07D233/68 , C07D233/90 , C07D249/12
Abstract: Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
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公开(公告)号：US10954192B2
公开(公告)日：2021-03-23
申请号：US16505843
申请日：2019-07-09
Inventor： Kenneth Bayles , Rongshi Li , Yan Liu
IPC: C07D207/34 , C07D231/16 , C07D233/68 , C07D233/90 , C07D249/12 , C07D207/333 , C07D233/64 , A61P31/04 , A61P35/00
Abstract: Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
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公开(公告)号：US10414725B2
公开(公告)日：2019-09-17
申请号：US15743427
申请日：2016-07-15
Inventor： Kenneth Bayles , Rongshi Li , Yan Liu
IPC: C07D207/34 , C07D231/16 , C07D233/64 , C07D233/68 , C07D233/90 , C07D249/12 , C07D207/333 , A61P31/04 , A61P35/00
Abstract: Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
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公开(公告)号：US20190330147A1
公开(公告)日：2019-10-31
申请号：US16505843
申请日：2019-07-09
Inventor： Kenneth Bayles , Rongshi Li , Yan Liu
IPC: C07D207/34 , A61P35/00 , A61P31/04 , C07D207/333 , C07D231/16 , C07D233/90 , C07D233/68 , C07D233/64 , C07D249/12
Abstract: Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
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