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公开(公告)号：US11497732B2
公开(公告)日：2022-11-15
申请号：US16534912
申请日：2019-08-07
发明人： Loic Patrick Le Hir de Fallois , Charles Q. Meng , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
IPC分类号： A61K31/422 , A61K47/14 , C07D491/107 , C07D261/04 , C07D471/04 , A01N43/80 , A61K9/00 , A61K47/10 , A61K31/415 , A61K31/42 , C07D413/04 , A61K9/10 , A61K9/08 , A61K9/107
摘要： This invention relates to long-acting injectable compositions for combating parasites in animals, comprising at least one isoxazoline active agent, a liquid PEG and/or a neutral oil, optionally a co-solvent, and optionally a pharmaceutically acceptable additive or excipient. This invention also provides new isoxazoline active agents with long-lasting efficacy against ectoparasites. The invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the novel isoxazoline compounds and long-acting injectable compositions of the invention to the animal in need thereof.
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2.发明授权公开(公告)号：US11484528B2
公开(公告)日：2022-11-01
申请号：US16588439
申请日：2019-09-30
摘要： This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
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3.发明授权公开(公告)号：US10561641B2
公开(公告)日：2020-02-18
申请号：US15054260
申请日：2016-02-26
摘要： This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
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4.发明申请公开(公告)号：US20200038370A1
公开(公告)日：2020-02-06
申请号：US16534912
申请日：2019-08-07
发明人： Loic Patrick Le Hir de Fallois , Charles Q. Meng , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
IPC分类号： A61K31/415 , A61K31/42 , A61K31/422 , C07D413/04 , A61K47/14 , C07D491/107 , C07D261/04 , C07D471/04 , A01N43/80 , A61K9/00 , A61K47/10
摘要： This invention relates to long-acting injectable compositions for combating parasites in animals, comprising at least one isoxazoline active agent, a liquid PEG and/or a neutral oil, optionally a co-solvent, and optionally a pharmaceutically acceptable additive or excipient. This invention also provides new isoxazoline active agents with long-lasting efficacy against ectoparasites. The invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the novel isoxazoline compounds and long-acting injectable compositions of the invention to the animal in need thereof.
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公开(公告)号：US12083100B1
公开(公告)日：2024-09-10
申请号：US17938063
申请日：2022-10-05
发明人： Loic Patrick Le Hir de Fallois , Charles Q. Meng , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
IPC分类号： A61K31/422 , A01N43/80 , A61K9/00 , A61K31/415 , A61K31/42 , A61K47/10 , A61K47/14 , C07D261/04 , C07D413/04 , C07D471/04 , C07D491/107 , A61K9/08 , A61K9/10 , A61K9/107
CPC分类号： A61K31/415 , A01N43/80 , A61K9/0019 , A61K31/42 , A61K31/422 , A61K47/10 , A61K47/14 , C07D261/04 , C07D413/04 , C07D471/04 , C07D491/107 , A61K9/0095 , A61K9/08 , A61K9/10 , A61K9/107
摘要： This invention relates to long-acting injectable compositions for combating parasites in animals, comprising at least one isoxazoline active agent, a liquid PEG and/or a neutral oil, optionally a co-solvent, and optionally a pharmaceutically acceptable additive or excipient. This invention also provides new isoxazoline active agents with long-lasting efficacy against ectoparasites. The invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the novel isoxazoline compounds and long-acting injectable compositions of the invention to the animal in need thereof.
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公开(公告)号：US20210299104A1
公开(公告)日：2021-09-30
申请号：US17327929
申请日：2021-05-24
IPC分类号： A61K31/42 , A61K9/00 , A61K31/422 , A61K47/22 , A61K47/10
摘要： This invention relates to extended release injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a pharmaceutically acceptable polymer, and a solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the extended release injectable formulations of the invention to the animal in need thereof.
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7.发明申请公开(公告)号：US20200179345A1
公开(公告)日：2020-06-11
申请号：US16788750
申请日：2020-02-12
发明人： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC分类号： A61K31/42 , A61K47/42 , A61K31/325 , A01N43/80 , A61K31/194 , A61K47/44 , A61K47/36 , A61K47/32 , A61K47/14 , A61K9/00 , A61K47/12 , A61K47/10 , A61K31/437 , A23K20/00 , A61K31/27 , A61K31/365 , A61K31/7048 , A61K31/4985 , C07D261/04 , A61K45/06
摘要： This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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公开(公告)号：US10596156B2
公开(公告)日：2020-03-24
申请号：US15936778
申请日：2018-03-27
发明人： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC分类号： A61K31/42 , A61K31/194 , A61K31/27 , A61K31/325 , A61K31/365 , A61K31/437 , A61K31/4985 , A61K31/7048 , A61K45/06 , A61K47/10 , C07D261/04 , A23K20/00 , A61K9/00 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/44 , A01N43/80 , A61K47/42
摘要： This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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9.发明申请公开(公告)号：US20200022959A1
公开(公告)日：2020-01-23
申请号：US16588439
申请日：2019-09-30
摘要： This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
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