公开(公告)号：US11364070B2

公开(公告)日：2022-06-21

申请号：US16254879

申请日：2019-01-23

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Bruce R. Forsyth ,  Matthew Ryan Dewitt ,  Hong Cao ,  Timothy A. Ostroot

IPC: A61B18/14 ,  A61N1/32 ,  A61M5/158 ,  A61B18/00

Abstract: Novel and versatile apparatuses for delivering one or more of thermal ablation and irreversible electroporation therapies to target tissue. In some examples, a device includes at its distal end a plurality of electrodes that can be advanced or retracted to pierce patient tissue, with a variable position and size shaft electrode provided near the distal end of the device to allow manipulation of therapy fields to achieve various tissue destruction field shapes. A number of method of use examples are described as well.

公开(公告)号：US11045648B2

公开(公告)日：2021-06-29

申请号：US16188343

申请日：2018-11-13

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Matthew Ryan Dewitt ,  Bruce R. Forsyth ,  Hong Cao

IPC: A61N1/32 ,  A61N1/04 ,  A61B18/14 ,  A61B18/00

Abstract: Biological cell destruction is achieved through a combination of injection of a substance and application of an electrical field. The substance, such as a cationic polymer, is selected for its electrical characteristics which can add to the transmembrane electric field of a cell when the electrical field is applied. In some examples, electrical field application is performed to encourage spatial concentration of the injected substance favorable to increased transmembrane field strength. The biological cell or cells are destroyed primarily through irreversible electroporation.