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公开(公告)号：US12121288B2
公开(公告)日：2024-10-22
申请号：US17204150
申请日：2021-03-17
Inventor： Bruce R. Forsyth , Chun Wang , Samuel Hanson
CPC classification number: A61B18/1477 , A61B18/1485 , A61L27/3641 , A61B2018/00154 , A61B2018/00333 , A61B2018/00345 , A61B2018/00452 , A61B2018/00494 , A61B2018/00511 , A61B2018/00529 , A61B2018/00541 , A61B2018/00547 , A61B2018/00559 , A61B2018/00613 , A61L2400/06
Abstract: In some aspects, the present disclosure pertains to methods of treating a tissue volume comprising (a) administering an implantable composition comprising a releasable membrane-active agent to a target site such that the membrane-active agent is locally released to the tissue volume and (b) performing irreversible, reversible and/or thermal treatment by application of a pulsed electric field to the tissue volume. In other aspects, the present disclosure pertains to embolic compositions that comprise releasable membrane-active agents.
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公开(公告)号：US10921056B2
公开(公告)日：2021-02-16
申请号：US16236239
申请日：2018-12-28
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Jan Weber , Bruce R. Forsyth
Abstract: Medical devices and methods for drying medical devices are disclosed. An example method for drying a medical device may include disposing a medical device within a drying apparatus. The drying apparatus may include a variable frequency microwave heating device. The medical device may include a substrate, the substrate including an active pharmaceutical ingredient and a solvent. The method may also include heating the medical device with the drying apparatus. Heating may evaporate at least a portion of the solvent.
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公开(公告)号：US11045648B2
公开(公告)日：2021-06-29
申请号：US16188343
申请日：2018-11-13
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Matthew Ryan Dewitt , Bruce R. Forsyth , Hong Cao
Abstract: Biological cell destruction is achieved through a combination of injection of a substance and application of an electrical field. The substance, such as a cationic polymer, is selected for its electrical characteristics which can add to the transmembrane electric field of a cell when the electrical field is applied. In some examples, electrical field application is performed to encourage spatial concentration of the injected substance favorable to increased transmembrane field strength. The biological cell or cells are destroyed primarily through irreversible electroporation.
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公开(公告)号：US20160361047A1
公开(公告)日：2016-12-15
申请号：US15175672
申请日：2016-06-07
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： James P. ROHL , Katharine Eckerline , Bruce R. Forsyth , Charles Rundquist , David Robert Wulfman , Jason Ott , David John Lehse
CPC classification number: A61B10/04 , A61B10/0283 , A61B2010/045 , A61B2017/00862 , A61B2562/12 , A61L31/022 , A61M1/0056
Abstract: A needle device for obtaining a tissue sample includes a distal member extending longitudinally from a proximal end to a distal end and including a distal channel extending longitudinally therethrough, the distal member formed of a first material selected to permit flexing of the distal member, a proximal member extending longitudinally from a proximal end to a distal end and including a proximal channel extending longitudinally therethrough, the proximal member formed of a second material selected to provide axial and torsional strength therealong in combination with a coupler for connecting the distal member and the proximal member, the coupler extending longitudinally from a proximal end configured to engage the distal end of the proximal member to a distal end configured to engage the proximal end of the distal member.
Abstract translation: 用于获得组织样本的针装置包括从近端到远端纵向延伸的远端构件，并且包括纵向延伸穿过其中的远端通道，所述远端构件由选择为允许远端构件弯曲的第一材料形成， 构件，其从近端纵向延伸到远端，并且包括纵向延伸穿过其中的近侧通道，所述近端构件由第二材料形成，所述近侧构件被选择成与用于连接远端构件和近端构件的联接器一起提供轴向和扭转强度 ，所述联接器从近端延伸，所述近端被构造成接合所述近端构件的远端到构造为接合所述远端构件的近端的远端。
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公开(公告)号：US20250009416A1
公开(公告)日：2025-01-09
申请号：US18891170
申请日：2024-09-20
Inventor： Bruce R. Forsyth , Chun Wang , Samuel Hanson
Abstract: In some aspects, the present disclosure pertains to methods of treating a tissue volume comprising (a) administering an implantable composition comprising a releasable membrane-active agent to a target site such that the membrane-active agent is locally released to the tissue volume and (b) performing irreversible, reversible and/or thermal treatment by application of a pulsed electric field to the tissue volume. In other aspects, the present disclosure pertains to embolic compositions that comprise releasable membrane-active agents.
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Patent Agency Ranking
公开(公告)号：US11992260B2
公开(公告)日：2024-05-28
申请号：US17216871
申请日：2021-03-30
Applicant: Boston Scientific Scimed, Inc.
Inventor： Timothy A. Ostroot , Bruce R. Forsyth , Hong Cao , Larry D. Canady, Jr. , Jonathan Tyler Gorzycki
CPC classification number: A61B18/1492 , A61B18/1206 , G16H40/67 , A61B2018/00577 , A61B2018/00779 , A61B2018/00827 , A61B2018/00892 , A61B2018/1467
Abstract: Ablation probes and methods of their use. Example probes include probe circuits configured to provide identifying information for the probe itself. The probe circuits may sense probe usage and/or age to determine probe end of life (EOL). In response to EOL, the probe circuit generates an output indicating EOL. The probe electronic circuit may also be configured to monitor probe usage via impedance or other features, independent of such operation by an ablation pulse generator.
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公开(公告)号：US10799283B2
公开(公告)日：2020-10-13
申请号：US14808483
申请日：2015-07-24
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Bruce R. Forsyth , James P. Rohl , David J. Lehse , Joel T. Eggert , Devon N. Arnholt
Abstract: Tissue regions are treated using a multiple lead electrode probe. A plurality of electrodes may be disposed about an elongate shaft. The elongate shaft may be slidably disposed within a lumen of a delivery sheath. One or more probes including one or more electrically active regions may also be slidably disposed within the delivery sheath. The one or more probes may be configured to extend radially about the elongate shaft. The plurality of electrodes and the electrically active regions may be individually connected to a control and power unit through individual channels.
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公开(公告)号：US20170333185A1
公开(公告)日：2017-11-23
申请号：US15595176
申请日：2017-05-15
Applicant: Boston Scientific Scimed Inc.
Inventor： Jan Weber , Haiying Zhou , Bruce R. Forsyth
CPC classification number: A61F2/2415 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2210/0076 , A61F2250/0017 , A61F2250/0023 , A61F2250/0028 , A61F2250/0036 , A61F2250/0076 , A61L27/14 , A61L27/306 , B32B27/02 , C08K3/22 , C08K2003/2227 , C08K2003/2241 , C08K2003/2255 , D01F8/00 , D04H1/541 , D04H3/147
Abstract: Examples herein include prosthetic valves, valve leaflets and related methods. In an example, a prosthetic valve is included having a plurality of leaflets. The leaflets can each have a root portion and an edge portion substantially opposite the root portion and movable relative to the root portion. The leaflets can include a fibrous matrix including polymeric fibers having an average diameter of about 10 nanometers to about 10 micrometers. A coating can surround the polymeric fibers within the fibrous matrix. The coating can have a thickness of about 3 to about 30 nanometers. The coating can be formed of a material selected from the group consisting of a metal oxide, a nitride, a carbide, a sulfide, or fluoride. In an example, a method of making a valve is included. Other examples are also included herein.
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公开(公告)号：US20250072881A1
公开(公告)日：2025-03-06
申请号：US18817557
申请日：2024-08-28
Applicant: Boston Scientific Scimed, Inc.
Inventor： Aiden Flanagan , Bruce R. Forsyth
Abstract: Method and systems for closing an opening formed during a medical procedure are disclosed. An example method may include advancing a needle through patient tissue to form an opening into a bile duct region, performing an intervention within the bile duct region, and advancing an embolic gel into the opening to close the opening.
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公开(公告)号：US11723545B2
公开(公告)日：2023-08-15
申请号：US17115503
申请日：2020-12-08
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh Hirasingh Thakur , Jeffrey E. Stahmann , Viktoria A. Averina , Deepa Mahajan , Bruce R. Forsyth
IPC: A61B5/0205 , A61B5/00 , A61B5/0537 , A61B5/11 , A61B7/00 , A61B5/08 , A61B5/024
CPC classification number: A61B5/0205 , A61B5/0537 , A61B5/1116 , A61B5/1118 , A61B5/4875 , A61B5/7282 , A61B7/00 , A61B5/024 , A61B5/0816
Abstract: Systems and methods to determine an indication of patient dehydration are disclosed, including receiving first and second physiologic information of a patient, the first physiologic information including heart sound information of the patient and the second physiologic information different than the first physiologic information, and determining the indication of patient dehydration using the received first and second physiologic information.
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