公开(公告)号：US20180265851A1

公开(公告)日：2018-09-20

申请号：US15763677

申请日：2016-09-30

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Chetana RAO-NAIK ,  Ganapathy N. SARMA ,  Akbar NAYEEM

IPC: C12N9/10 ,  C12P21/00 ,  A61K47/68

CPC classification number: C12N9/1044 ,  A61K47/68 ,  A61K47/6803 ,  A61K47/6849 ,  C12P21/00 ,  C12Y203/02013

Abstract: Transglutaminase variants capable of conjugating an antibody that is not conjugated by wild-type transglutaminase from Streptomyces mobaraensis.