公开(公告)号：US20210355113A1

公开(公告)日：2021-11-18

申请号：US17261968

申请日：2019-07-20

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： James Aaron BALOG ,  Steven P. SEITZ ,  Jay A. MARKWALDER ,  David K. WILLIAMS ,  Weifang SHAN ,  Susheel Jethanand NARA ,  Saumya ROY ,  Srinivas CHERUKU ,  Nagalakshmi PULICHARLA

IPC: C07D405/14 ,  C07D405/10 ,  C07D413/14 ,  C07D313/08 ,  C07D413/10 ,  C07D417/14 ,  C07D307/79 ,  C07K16/28

Abstract: The present invention provides compounds of formula (I) wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.

公开(公告)号：US20210299126A1

公开(公告)日：2021-09-30

申请号：US17261954

申请日：2019-07-22

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： James Aaron BALOG ,  Jay A. MARKWALDER ,  Weifang SHAN ,  David K. WILLIAMS ,  Susheel Jethanand NARA ,  Saumya ROY ,  Soodamani THANGAVEL ,  Srinivas CHERUKU ,  Ramesh Kumar SISTLA

IPC: A61K31/506 ,  A61K39/395 ,  C07D403/10 ,  C07D403/14 ,  C07D413/10 ,  C07D417/10 ,  C07D213/75 ,  C07D401/14 ,  A61K31/4439 ,  A61K31/4418 ,  A61K31/496 ,  A61K31/501 ,  A61K31/519 ,  C07D405/14 ,  C07D487/04 ,  C07D417/14 ,  A61K31/5377 ,  A61K31/4725 ,  C07D413/14 ,  C07D213/74

Abstract: The present invention provides compounds of formula (I): wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.