公开(公告)号：US10766946B2

公开(公告)日：2020-09-08

申请号：US15760413

申请日：2016-09-22

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Stanley Richard Krystek, Jr. ,  Tracy S. Mitchell ,  Michael L. Gosselin ,  Dasa Lipovsek ,  Juhi Juneja

IPC: C07K14/78 ,  C07K14/765 ,  C12N15/85

Abstract: Provided herein are polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin. Also provided are fusion molecules comprising a serum albumin binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.

公开(公告)号：US11434275B2

公开(公告)日：2022-09-06

申请号：US16748085

申请日：2020-01-21

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Stanley Richard Krystek, Jr. ,  Tracy S. Mitchell ,  Michael L. Gosselin ,  Dasa Lipovsek ,  Juhi Juneja

IPC: C07K14/78 ,  C07K14/765 ,  C12N15/85

Abstract: Provided herein are polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin. Also provided are fusion molecules comprising a serum albumin binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.