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    Natriuretic compounds, conjugates, and uses thereof
    4.
    发明申请
    Natriuretic compounds, conjugates, and uses thereof 失效
    利尿钠化合物，缀合物及其用途

    公开(公告)号：US20060172933A1

    公开(公告)日：2006-08-03

    申请号：US10999761

    申请日：2004-11-30

    申请人： Kenneth James ,  Balasingham Radhakrishnan ,  Navdeep Malkar ,  Mark Miller ,  Nnochiri Ekwuribe

    发明人： Kenneth James ,  Balasingham Radhakrishnan ,  Navdeep Malkar ,  Mark Miller ,  Nnochiri Ekwuribe

    IPC分类号： A61K38/17 ,  C07K14/47

    CPC分类号： C07K14/58 ,  A61K38/00 ,  A61K47/60 ,  C07K14/72 ,  C07K16/26

    摘要： Modified natriuretic compounds and conjugates thereof are disclosed in the present invention. In particular, conjugated forms of hBNP are provided that include at least one modifying moiety attached thereto. The modified natriuretic compound conjugates retain activity for stimulating cGMP production, binding to NPR-A receptor, and in some embodiments an improved half-life in circulation as compared to unmodified counterpart natriuretic compounds. Oral, parenteral, enteral, subcutaneous, pulmonary, and intravenous forms of the compounds and conjugates may be prepared as treatments and/or therapies for heart conditions particularly congestive heart failure. Modifying moieties comprising oligomeric structures having a variety of lengths and configurations are also disclosed. Analogs of the natriuretic compound are also disclosed, having an amino acid sequence that is other than the native sequence.

    摘要翻译： 本发明公开了改良的利尿钠化合物及其缀合物。 特别地，提供了缀合形式的hBNP，其包括与其连接的至少一个修饰部分。 修饰的利尿钠化合物缀合物保留刺激cGMP产生，结合NPR-A受体的活性，并且在一些实施方案中，与未修饰的对应利钠化合物相比，循环中的半衰期改善。 口服，胃肠外，肠内，皮下，肺和静脉内形式的化合物和缀合物可以制备为用于心脏状况的治疗和/或治疗，特别是充血性心力衰竭。 还公开了包含具有各种长度和构型的寡聚结构的修饰部分。 还公开了利尿钠化合物的类似物，其具有不同于天然序列的氨基酸序列。

    EVAPORATOR FOR SAGD PROCESS
    6.
    发明申请
    EVAPORATOR FOR SAGD PROCESS 审中-公开
    蒸发器用于SAGD过程

    公开(公告)号：US20150122631A1

    公开(公告)日：2015-05-07

    申请号：US14594884

    申请日：2015-01-12

    申请人： Kenneth James ,  Bob Nabata

    发明人： Kenneth James ,  Bob Nabata

    IPC分类号： C02F1/04 ,  B01D1/28 ,  B01D1/00

    CPC分类号： C02F1/048 ,  B01D1/0082 ,  B01D1/065 ,  B01D1/28 ,  B01D17/0214 ,  C02F1/04 ,  C02F1/08 ,  E21B43/34 ,  Y10S159/901 ,  Y10S203/18

    摘要： A closed loop contaminant control system for an evaporative water purification process at an oil recovery facility includes an evaporator having a water inlet, a distilled water discharge, and an oil and brine water discharge. A sump in the evaporator is divided by an oil skimming weir into a main sump and a blowdown sump, with the oil and brine water discharge located proximate the blowdown sump and the steam discharge located above the oil and brine discharge. A distillate tank receives distilled water from the evaporator and discharges the distilled water. The distillate tank has a level controller, other controllers provided for the system include a distilled water flow meter, a blowdown flow meter, a cycle controller, a total flow controller, a hardness controller, and a silica controller.

    摘要翻译： 用于油回收设备处的蒸发水净化过程的闭环污染物控制系统包括具有进水口，蒸馏水排出口以及油和盐水水排出口的蒸发器。 蒸发器中的一个油槽被一个油撇水堰分成一个主油槽和一个排污池，其中油和盐水排放位于排污池附近，蒸汽排放位于油和盐水排放之上。 馏出液从蒸发器中接收蒸馏水并排出蒸馏水。 蒸馏罐具有液位控制器，为系统提供的其他控制器包括蒸馏水流量计，排污流量计，循环控制器，总流量控制器，硬度控制器和二氧化硅控制器。

    BITUMEN RECOVERY PROCESS
    8.
    发明申请
    BITUMEN RECOVERY PROCESS 审中-公开
    BITUM RECOVERY PROCESS

    公开(公告)号：US20140054028A1

    公开(公告)日：2014-02-27

    申请号：US13971893

    申请日：2013-08-21

    申请人： Laureen Little ,  Kenneth James ,  Bob Nabata

    发明人： Laureen Little ,  Kenneth James ,  Bob Nabata

    IPC分类号： E21B43/24

    CPC分类号： E21B43/2401 ,  E21B43/24

    摘要： 1. A bitumen recovery process where the process includes the following steps: a) Drilling a single well into a bitumen deposit; b) Equipping the well with a heating element, a solvent injecting member, and a bitumen recovering member; c) Injecting the well with a solvent; d) Heating the solvent with the heating element to a vapor state; e) Mixing the solvent vapour with bitumen in the deposit; f) Draining the bitumen to the bottom of the well; g) Heating the bitumen to keep its viscosity low; h) Evaporating part of solvent entrapped in the bitumen by the heating element; i) Recovering the bitumen and traces of water from the well; j) Condensing the solvent inside the well for further mixing with the bitumen in the deposit; k) Repeating steps h through j, where the majority of the solvent does not leave the well during the process.

    摘要翻译： 1.沥青回收过程，其过程包括以下步骤：a）将单井钻入沥青沉积物; b）用加热元件，溶剂注入构件和沥青回收构件来装备井; c）用溶剂注入井; d）将加热元件的溶剂加热至蒸汽状态; e）将溶剂蒸气与沉淀物中的沥青混合; f）将沥青排入井底; g）加热沥青以保持其粘度低; h）通过加热元件将部分溶剂蒸发掉在沥青中; i）从井中回收沥青和水痕迹; j）冷凝孔内的溶剂，以进一步与沉积物中的沥青混合; k）重复步骤h至j，其中大部分溶剂在该过程中不会离开井。

    METHODS FOR PRESERVING FRESH PRODUCE
    9.
    发明申请
    METHODS FOR PRESERVING FRESH PRODUCE 审中-公开
    保存新鲜生产方法

    公开(公告)号：US20130309380A1

    公开(公告)日：2013-11-21

    申请号：US13951935

    申请日：2013-07-26

    申请人： Chao Chen ,  Xiaoling Dong ,  Kenneth James

    发明人： Chao Chen ,  Xiaoling Dong ,  Kenneth James

    IPC分类号： A23B7/157

    CPC分类号： A23B7/157 ,  A23B7/04 ,  A23B7/0441 ,  A23B7/05 ,  A23B7/10 ,  Y02A40/943

    摘要： Methods of preserving fresh produce with a produce preservative which extends the shelf life of fresh produce, particularly cut fresh produce, and preserves the texture, flavor, appearance, crispness, and color of the fresh produce, particularly the exposed surface of the fresh produce, are provided. The method comprises: providing a solution of produce preservative comprising: water; a preservative cation which is selected from the group consisting of a strontium ion, lithium ion, barium ion, aluminum ion, copper ion, ammonium ion, iron ion, manganese ion, potassium ion, or mixtures thereof; and ascorbate ions, or erythorbate ions; wherein the ascorbate ions or erythorbate ions and the preservative cation are present in an ion ratio of preferably from 0.2:1 to 8:1, more preferably 0.75:1 to 8:1, even more preferably from 1:1 to 4:1, yet more preferably 1.5:1 to 3:1; most preferably 1.1:1 to 2.5:1; and, applying said produce preservative to the produce. The invention also relates to fresh produce preserved with the produce preservatives.

    摘要翻译： 用生产防腐剂保存新鲜产品的方法，其延长新鲜产品的保存期限，特别是切割新鲜产品，并且保留新鲜农产品，特别是新鲜农产品的暴露表面的质地，风味，外观，脆性和颜色， 被提供。 该方法包括：提供产品防腐剂的溶液，包括：水; 选自锶离子，锂离子，钡离子，铝离子，铜离子，铵离子，铁离子，锰离子，钾离子或其混合物的防腐阳离子; 和抗坏血酸离子，或赤藓酸离子; 其中抗坏血酸离子或异硫氰酸根离子和防腐阳离子以优选0.2:1至8:1，更优选0.75:1至8:1，甚至更优选1：1至4:1的离子比存在， 还更优选为1.5：1至3：1; 最优选为1.1：1至2.5：1; 并将所述产品防腐剂施用于产品。 本发明还涉及用产品防腐剂保存的新鲜产品。

    Compact Evaporator for Modular Portable SAGD Process
    10.
    发明申请
    Compact Evaporator for Modular Portable SAGD Process 有权
    用于模块化便携式SAGD工艺的紧凑型蒸发器

    公开(公告)号：US20120193213A1

    公开(公告)日：2012-08-02

    申请号：US13087708

    申请日：2011-04-15

    申请人： Kenneth James

    发明人： Kenneth James

    IPC分类号： C02F1/08 ,  B01D3/02 ,  C02F1/18

    CPC分类号： B01D1/065 ,  B01D1/28 ,  B01D1/30 ,  C02F1/041 ,  C02F1/08 ,  C02F1/18 ,  C02F2201/008 ,  Y10S159/02 ,  Y10S159/901 ,  Y10S165/135 ,  Y10S165/169 ,  Y10S203/08

    摘要： A modular portable evaporator system for use in a Steam Assisted Gravity Drainage (SAGD) systems having an evaporator, with a sump comprising an oil skimming weir, a short tube vertical heat exchanger including an outer shell containing the short tubes provided for lower water circulation rate. A system further having, external to the evaporator, a compressor compressing evaporated steam from the tube-side of the heat exchanger and routing to the shell side of the same exchanger, a distillate tank to collect hot distilled water, a recirculation pump to introduce liquids from the sump into the heat exchanger and an external demister protecting the compressor from liquid impurities. The evaporator system receives produced water from the process into the sump and provides cleaned hot water to the boiler.

    摘要翻译： 一种用于具有蒸发器的蒸汽辅助重力排水（SAGD）系统中的模块化便携式蒸发器系统，具有包括油撇去堰的贮槽，短管垂直热交换器，其包括外壳，所述外壳包含用于较低水循环速率的短管 。 在蒸发器外还具有压缩从热交换器的管侧蒸发的蒸汽并且转移到同一交换器的壳侧的压缩机，用于收集热蒸馏水的馏出罐，用于引入液体的再循环泵 从贮槽进入热交换器和外部除雾器，保护压缩机免受液体杂质的影响。 蒸发器系统将生产的水从工艺中接收到贮槽中，并向锅炉提供清洁的热水。