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公开(公告)号:US10266548B2
公开(公告)日:2019-04-23
申请号:US15438254
申请日:2017-02-21
发明人: Marion Hitchcock , Anne Mengel , Vera Pütter , Gerhard Siemeister , Antje Margret Wengner , Hans Briem , Knut Eis , Volker Schulze , Amaury Ernesto Fernandez-Montalvan , Stefan Prechtl , Simon Holton , Jörg Fanghänel , Philip Lienau , Cornelia Preusse , Mark Jean Gnoth
IPC分类号: C07D401/14 , C07D498/04 , C07D405/14 , C07D413/14 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D403/04
摘要: Compounds of formula (I) which are inhibitors of Bub 1 kinase, processes for their production and their use as pharmaceuticals.
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公开(公告)号:US10604532B2
公开(公告)日:2020-03-31
申请号:US16360811
申请日:2019-03-21
发明人: Marion Hitchcock , Anne Mengel , Vera Pütter , Gerhard Siemeister , Antje Margret Wengner , Hans Briem , Knut Eis , Volker Schulze , Amaury Ernesto Fernandez-Montalvan , Stefan Prechtl , Simon Holton , Jörg Fanghänel , Philip Lienau , Cornelia Preusse , Mark Jean Gnoth
IPC分类号: C07D401/14 , C07D498/04 , C07D405/14 , C07D413/14 , A01H6/36 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D403/04
摘要: Compounds of formula (I) which are inhibitors of Bub 1 kinase, processes for their production and their use as pharmaceuticals.
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公开(公告)号:US09265763B2
公开(公告)日:2016-02-23
申请号:US14350160
申请日:2012-10-04
发明人: Marion Hitchcock , Anne Mengel , Vera Pütter , Gerhard Siemeister , Antje Margret Wengner , Hans Briem , Knut Eis , Volker Schulze , Amaury Ernesto Fernandez-Montalvan , Stefan Prechtl , Simon Holton , Jörg Fanghänel , Philip Lienau , Cornelia Preusse , Mark Jean Gnoth
IPC分类号: C07D401/14 , A61K31/506 , C07D405/14 , C07D413/14 , C07D498/04 , A61K31/5377 , A61K31/5383 , A61K45/06
摘要: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
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公开(公告)号:US20140315934A1
公开(公告)日:2014-10-23
申请号:US14365895
申请日:2012-12-17
发明人: Marion Hitchcock , Anne Mengel , Anja Richter , Hans Briem , Knut Eis , Vera Pütter , Gerhard Siemeister , Stefan Prechtl , Amaury Ernesto Fernandez-Montalvan , Christian Stegmann , Simon Holton , Mark Jean Gnoth , Cornelia Preuße
IPC分类号: C07D401/14 , C07D405/14 , A61K31/506
CPC分类号: C07D401/14 , A61K31/506 , C07D405/14
摘要: Compounds of formula (I) and their use as pharmaceutical.
摘要翻译: 式(I)化合物及其作为药物的用途。
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5.SUBSTITUTED BENZYLINDAZOLES FOR USE AS BUB1 KINASE INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES 审中-公开
标题翻译: 用作BUB1激酶抑制剂治疗高增殖性疾病的替代苄基胆碱公开(公告)号:US20140249133A1
公开(公告)日:2014-09-04
申请号:US14350160
申请日:2012-10-04
发明人: Marion Hitchcock , Anne Mengel , Vera Pütter , Gerhard Siemeister , Antje Margret Wengner , Hans Briem , Knut Eis , Volker Schulze , Amaury Ernesto Fernandez-Montalvan , Stefan Prechtl , Simon Holton , Jörg Fanghänel , Philip Lienau , Cornelia Preusse , Mark Jean Gnoth
IPC分类号: C07D498/04 , A61K31/506 , A61K31/5383 , C07D405/14 , A61K31/5377 , C07D413/14 , C07D401/14 , A61K45/06
CPC分类号: C07D498/04 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , C07D413/14
摘要: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
摘要翻译: 作为Bub1激酶抑制剂的式(I)化合物,其制备方法及其作为药物的用途。
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