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1.发明授权Obtaining cocoa extracts rich in bioactive peptides with ACE and PEP enzyme inhibitory activity 有权用ACE和PEP酶抑制活性获得富含生物活性肽的可可提取物公开(公告)号：US08946383B2
公开(公告)日：2015-02-03
申请号：US13056909
申请日：2008-08-01
申请人： Begoña Muguerza Marquínez , Honorato Monzo Oltra , Natalia Alepuz Rico , Esther Bataller Leiva , Salvador Genoves Martínez , Maria Enrique López , Patricia Guerola Guerola , Daniel Ramon Vidal
发明人： Begoña Muguerza Marquínez , Honorato Monzo Oltra , Natalia Alepuz Rico , Esther Bataller Leiva , Salvador Genoves Martínez , Maria Enrique López , Patricia Guerola Guerola , Daniel Ramon Vidal
CPC分类号： A23G1/0006 , A23G1/0009 , A23G1/30 , A23L33/105 , A23L33/18 , A23V2002/00 , A61K38/011 , A61K38/08 , A61K38/10 , C12Y304/15001 , A23V2200/326 , A23V2250/21 , A23V2200/02
摘要： The present invention relates to obtaining bioactive peptides from plant raw materials, specifically cocoa extracts, by means of enzyme treatment. Said biopeptides have angiotensin converting enzyme (ACE) and prolyl endopeptidase enzyme (PEP) inhibitory activity in vitro and/or antioxidant activity in vivo, being able to be used in the food, dietetic and pharmaceutical industry.
摘要翻译： 本发明涉及通过酶处理从植物原料，特别是可可提取物获得生物活性肽。 所述生物肽具有血管紧张素转换酶（ACE）和脯氨酰内肽酶（PEP）体内抑制活性和/或体内抗氧化活性，能够用于食品，饮食和制药工业。
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2.发明申请OBTAINING COCOA EXTRACTS RICH IN BIOACTIVE PEPTIDES WITH ACE AND PEP ENZYME INHIBITORY ACTIVITY 有权获得丰富的生物活性肽与ACE和PEP酶抑制活性的提取物公开(公告)号：US20110213122A1
公开(公告)日：2011-09-01
申请号：US13056909
申请日：2008-08-01
申请人： Begona Muguerza Marquinez , Honorato Monzo Oltra , Natalia Alepuz Rico , Esther Bataller Leiva , Salvador Genoves Martínez , Maria Enrique López , Patricia Martorell Guerola , Daniel Ramon Vidal
发明人： Begona Muguerza Marquinez , Honorato Monzo Oltra , Natalia Alepuz Rico , Esther Bataller Leiva , Salvador Genoves Martínez , Maria Enrique López , Patricia Martorell Guerola , Daniel Ramon Vidal
CPC分类号： A23G1/0006 , A23G1/0009 , A23G1/30 , A23L33/105 , A23L33/18 , A23V2002/00 , A61K38/011 , A61K38/08 , A61K38/10 , C12Y304/15001 , A23V2200/326 , A23V2250/21 , A23V2200/02
摘要： The present invention relates to obtaining bioactive peptides from plant raw materials, specifically cocoa extracts, by means of enzyme treatment. Said biopeptides have angiotensin converting enzyme (ACE) and prolyl endopeptidase enzyme (PEP) inhibitory activity in vitro and/or antioxidant activity in vivo, being able to be used in the food, dietetic and pharmaceutical industry.
摘要翻译： 本发明涉及通过酶处理从植物原料，特别是可可提取物获得生物活性肽。 所述生物肽具有血管紧张素转换酶（ACE）和脯氨酰内肽酶（PEP）体内抑制活性和/或体内抗氧化活性，能够用于食品，饮食和制药工业。
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3.发明申请OBTAINMENT OF BIOACTIVE PRODUCTS FROM COCOA HAVING INHIBITORY ACTIVITY AGAINST THE PEP ENZYME AND ANTIOXIDANT AND/OR ANTINEURODEGENERATIVE ACTIVITY 审中-公开从具有抑制活性的COCOA获得的生物活性产物对PEP酶和抗氧化剂和/或抗原活性的活性公开(公告)号：US20130035291A1
公开(公告)日：2013-02-07
申请号：US13518787
申请日：2009-12-23
申请人： Esther Bataller Leiva , Salvador Genoves Martinez , Patricia Martorell Guerola , Daniel Ramon Vidal , Aida Ibañnez Lopez , Silvia Llopis Pla , Nuria Gonzalez Martinez , Honorato Monzo Oltra , Begoña Muguerza Marquinez
发明人： Esther Bataller Leiva , Salvador Genoves Martinez , Patricia Martorell Guerola , Daniel Ramon Vidal , Aida Ibañnez Lopez , Silvia Llopis Pla , Nuria Gonzalez Martinez , Honorato Monzo Oltra , Begoña Muguerza Marquinez
CPC分类号： A23G1/44 , A23L33/105
摘要： The present invention relates to the production of bioactive products from raw plant matter, namely cocoa extracts. The said products have one or more biopeptides with prolyl endopeptidase (PEP) enzyme inhibitory activity in vitro and/or antioxidant and/or antineurodegenerative capacity in vivo and can be used in dietetics and in the food and pharmaceutical industries.
摘要翻译： 本发明涉及从原始植物物质即可可提取物生产生物活性产物。 所述产品在体外具有一种或多种具有脯氨酰内肽酶（PEP）酶抑制活性的生物肽和/或体内抗氧化和/或抗血管变性能力，并可用于营养学和食品和制药行业。
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公开(公告)号：US20130121976A1
公开(公告)日：2013-05-16
申请号：US13634458
申请日：2010-03-12
申请人： Agusti Montserrat Carreras , Montserrat Andreu Corominas , Daniel Ramon Vidal , Salvador Genoves Martinez , Esther Bataller Leiva
发明人： Agusti Montserrat Carreras , Montserrat Andreu Corominas , Daniel Ramon Vidal , Salvador Genoves Martinez , Esther Bataller Leiva
IPC分类号： A61K35/74
CPC分类号： A61K35/74 , A61K35/744 , A61K35/747 , C12N1/18 , C12N1/20 , C12Q1/02 , C12R1/225 , C12R1/245 , C12R1/46
摘要： The present invention discloses strains of Lactobacillus and Streptococcus which have a capacity to degrade gliadin peptides involved in coeliac disease and which peptide degrading activity is stable under low pH and in the presence of mammalian digestive enzymes. These strains are suitable in a product for use in prevention and/or treatment of celiac disease.
摘要翻译： 本发明公开了具有降解涉及乳糜泻的麦醇溶蛋白肽的能力的乳杆菌和链球菌菌株，并且在低pH下和在哺乳动物消化酶存在下，肽降解活性是稳定的。 这些菌株适用于预防和/或治疗乳糜泻的产品。
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公开(公告)号：US20100034954A1
公开(公告)日：2010-02-11
申请号：US12524478
申请日：2007-07-24
CPC分类号： A23K50/40 , A23G1/0006 , A23G1/0009 , A23G1/002 , A23G1/02 , A23G1/32 , A23G1/56 , A23K10/14 , A23K10/30 , A23L5/25 , C07D473/10 , C07D473/12
摘要： The invention relates to a method for obtaining fibre-rich cocoa with low carbon hydrate and methylxanthine contents and resulting cocoa powder which is suitable for animal feed. The inventive method includes the following main steps in which: the whole cocoa beans undergo cleaning, deffating, treatment with alpha-amylase, centrifugation, extraction-washing and subsequent centrifugation, separation, drying and grinding.
摘要翻译： 本发明涉及一种获得具有低碳水合物和甲基黄嘌呤含量的富含纤维的可可粉的方法，所得的可可粉适用于动物饲料。 本发明的方法包括以下主要步骤，其中：整个可可豆经过清洁，脱浆，用α-淀粉酶处理，离心，萃取 - 洗涤和随后的离心，分离，干燥和研磨。
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公开(公告)号：US08735089B2
公开(公告)日：2014-05-27
申请号：US13520459
申请日：2010-01-08
申请人： Gianfranco Grompone , Marie-Christine Degivry , Daniel Ramon Vidal , Patricia Martorell Guerola , Nuria Gonzalez Martinez , Salvador Genoves Martinez , Sophie Legrain-Raspaud , Isabelle Chambaud , Raphaelle Bourdet-Sicard
发明人： Gianfranco Grompone , Marie-Christine Degivry , Daniel Ramon Vidal , Patricia Martorell Guerola , Nuria Gonzalez Martinez , Salvador Genoves Martinez , Sophie Legrain-Raspaud , Isabelle Chambaud , Raphaelle Bourdet-Sicard
IPC分类号： C12Q1/02
CPC分类号： A61K49/00 , C12Q1/02 , G01N33/5085
摘要： The present invention relates to a method using Caenorhabditis elegans for screening of food grade bacteria which have a protective effect against oxidative stress.
摘要翻译： 本发明涉及使用秀丽隐杆线虫对筛选对氧化应激有保护作用的食品级细菌的方法。
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7.发明申请PROCESS FOR OBTAINING POLYPHENOL-RICH COCOA POWDER WITH LOW FAT CONTENT AND COCOA THUS OBTAINED 审中-公开获得具有低脂肪含量的COCOA聚碳酸酯粉末的方法和获得的COCOA公开(公告)号：US20100062138A1
公开(公告)日：2010-03-11
申请号：US12280881
申请日：2007-02-27
申请人： Elena Cienfuegos-Jovellanos Fernandez , Maria Angeles Pasamar Fernandez , Jaisli Fritz Kurt , Francisco Javier Arcos Palacios , Daniel Ramon Vidal , Yolanda Castilla Escobar
发明人： Elena Cienfuegos-Jovellanos Fernandez , Maria Angeles Pasamar Fernandez , Jaisli Fritz Kurt , Francisco Javier Arcos Palacios , Daniel Ramon Vidal , Yolanda Castilla Escobar
IPC分类号： A23G1/48
CPC分类号： B01D15/00 , A23G1/0006 , A23G1/32 , A23G1/56 , A23V2002/00 , B01D15/08 , B01D15/424 , B01J20/26 , B01J20/285 , C07D311/62 , A23V2250/2132
摘要： The invention relates to a method for obtaining polyphenol-rich cocoa powder with a low fat content and to the cocoa thus obtained. The method optionally includes a phase comprising the purification of the polyphenols obtained from the defatted cocoa cake using an Amberlite column. The end product has a particle size of less than 3 mm for 99% of the particles and a polyphenol content of preferably between 60 and 90% and a fat content of less than 12% in relation to the weight of the dry matter.
摘要翻译： 本发明涉及一种获得具有低脂肪含量的多酚富可可粉和如此获得的可可的方法。 所述方法任选地包括使用Amberlite柱纯化由脱脂可可饼获得的多酚的相。 对于99％的颗粒，最终产品具有小于3mm的粒度，相对于干物质的重量，多酚含量优选为60至90％，脂肪含量小于12％。
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公开(公告)号：US20130078187A1
公开(公告)日：2013-03-28
申请号：US13520459
申请日：2010-01-08
申请人： Gianfranco Grompone , Marie-Christine Degivry , Daniel Ramon Vidal , Patricia Martorell Guerola , Nuria Gonzalez Martinez , Salvador Genoves Martinez , Sophie Legrain-Raspaud , Isabelle Chambaud , Raphaelle Bourdet-Sicard
发明人： Gianfranco Grompone , Marie-Christine Degivry , Daniel Ramon Vidal , Patricia Martorell Guerola , Nuria Gonzalez Martinez , Salvador Genoves Martinez , Sophie Legrain-Raspaud , Isabelle Chambaud , Raphaelle Bourdet-Sicard
IPC分类号： A61K49/00
CPC分类号： A61K49/00 , C12Q1/02 , G01N33/5085
摘要： The present invention relates to a method using Caenorhabditis elegans for screening of food grade bacteria which have a protective effect against oxidative stress.
摘要翻译： 本发明涉及使用秀丽隐杆线虫对筛选对氧化应激有保护作用的食品级细菌的方法。
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