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公开(公告)号：US20050187200A1
公开(公告)日：2005-08-25
申请号：US10987554
申请日：2004-11-12
申请人： Benjamin Auspitz , Alexis Borisy , Jason Fong , Nicole Hurst , Edward Jost-Price , Curtis Keith , Palaniyandi Manivasakam , Robyn Sackeyfio , Michael Slavonic , Brendan Smith , Grant Zimmermann
发明人： Benjamin Auspitz , Alexis Borisy , Jason Fong , Nicole Hurst , Edward Jost-Price , Curtis Keith , Palaniyandi Manivasakam , Robyn Sackeyfio , Michael Slavonic , Brendan Smith , Grant Zimmermann
IPC分类号： A61K9/00 , A61K9/20 , A61K31/5415 , A61K31/551 , A61K31/565 , A61K31/573 , A61K31/59 , A61K31/60 , A61K38/13 , A61K45/06
CPC分类号： A61K45/06 , A61K31/565 , A61K38/13 , A61K2300/00
摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
摘要翻译： 本发明的特征在于一种通过向患者施用三环化合物和任选的皮质类固醇或其它化合物来治疗被诊断患有免疫炎症疾病或有风险的患者的方法。 本发明还特征在于含有三环化合物和皮质类固醇或其它化合物的药物组合物，用于治疗或预防免疫炎性疾病。
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公开(公告)号：US20070010502A1
公开(公告)日：2007-01-11
申请号：US11517593
申请日：2006-09-07
申请人： Curtis Keith , Alexis Borisy , Grant Zimmermann , Edward Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael Foley , Michael Slavonic , Brendan Smith , Benjamin Auspitz
发明人： Curtis Keith , Alexis Borisy , Grant Zimmermann , Edward Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael Foley , Michael Slavonic , Brendan Smith , Benjamin Auspitz
IPC分类号： A61K31/573 , A61K31/519
CPC分类号： A61K31/565 , A61K9/0073 , A61K9/209 , A61K31/519 , A61K38/13 , A61K45/06 , A61K2300/00
摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
摘要翻译： 本发明的特征在于一种通过向患者施用四取代的嘧啶并嘧啶，单独或与一种或多种另外的试剂组合来治疗诊断患有或有风险发展免疫炎性疾病的患者的方法。 本发明还特征在于含有四取代的嘧啶并嘧啶与一种或多种另外的试剂组合的组合物。
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3.发明申请公开(公告)号：US20050119160A1
公开(公告)日：2005-06-02
申请号：US10966228
申请日：2004-10-15
申请人： Curtis Keith , Alexis Borisy , Grant Zimmermann , Edward Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael Foley , Michael Slavonic , Brendan Smith , Benjamin Auspitz
发明人： Curtis Keith , Alexis Borisy , Grant Zimmermann , Edward Jost-Price , Palaniyandi Manivasakam , Nicole Hurst , Michael Foley , Michael Slavonic , Brendan Smith , Benjamin Auspitz
IPC分类号： A61K9/00 , A61K9/20 , A61K31/415 , A61K31/519 , A61K31/525 , A61K31/5415 , A61K31/551 , A61K31/565 , A61K31/59 , A61K31/60 , A61K38/00 , A61K38/13 , A61K45/06
CPC分类号： A61K31/565 , A61K9/0073 , A61K9/209 , A61K31/519 , A61K38/13 , A61K45/06 , A61K2300/00
摘要： The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
摘要翻译： 本发明的特征在于一种通过向患者施用四取代的嘧啶并嘧啶，单独或与一种或多种另外的试剂组合来治疗诊断患有或有风险发展免疫炎性疾病的患者的方法。 本发明还特征在于含有四取代的嘧啶并嘧啶与一种或多种另外的试剂组合的组合物。
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公开(公告)号：US07335371B2
公开(公告)日：2008-02-26
申请号：US10716823
申请日：2003-11-19
申请人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
发明人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
CPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/573 , A61K45/06 , G01N33/6863 , G01N2500/10 , Y10S514/825 , Y10S514/826 , Y10S514/863 , Y10S514/866 , Y10S514/958 , A61K2300/00
摘要： The invention features methods and compositions for the treatment of immunonflammatory disorders.
摘要翻译： 本发明的特征在于用于治疗免疫炎症的方法和组合物。
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公开(公告)号：US20080280863A1
公开(公告)日：2008-11-13
申请号：US12036941
申请日：2008-02-25
申请人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
发明人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
CPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/573 , A61K45/06 , G01N33/6863 , G01N2500/10 , Y10S514/825 , Y10S514/826 , Y10S514/863 , Y10S514/866 , Y10S514/958 , A61K2300/00
摘要： The invention features methods and compositions for the treatment of immunoinflammatory disorders.
摘要翻译： 本发明的特征在于用于治疗免疫炎性疾病的方法和组合物。
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公开(公告)号：US06955815B2
公开(公告)日：2005-10-18
申请号：US10674744
申请日：2003-09-29
申请人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
发明人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
IPC分类号： A61K31/56 , A01N45/00 , A61K9/00 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/554 , A61K31/573 , A61K45/06 , A61P1/04 , A61P1/10 , A61P11/06 , A61P17/00 , A61P17/06 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/00 , A61P43/00 , G01N33/68
CPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/573 , A61K45/06 , G01N33/6863 , G01N2500/10 , Y10S514/825 , Y10S514/826 , Y10S514/863 , Y10S514/866 , Y10S514/958 , A61K2300/00
摘要： The invention features a pharmaceutical composition that includes amoxapine and a corticosteroid.
摘要翻译： 本发明的特征在于包含阿莫沙平和皮质类固醇的药物组合物。
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公开(公告)号：US06897206B2
公开(公告)日：2005-05-24
申请号：US10191149
申请日：2002-07-09
申请人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
发明人： Robyn Sackeyfio , Jason Fong , Nicole Hurst , Palaniyandi Manivasakam , Edward Roydon Jost-Price , Grant Zimmermann , Curtis Keith , Alexis Borisy
IPC分类号： A61K31/56 , A01N45/00 , A61K9/00 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/554 , A61K31/573 , A61K45/06 , A61P1/04 , A61P1/10 , A61P11/06 , A61P17/00 , A61P17/06 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/00 , A61P43/00 , G01N33/68
CPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/573 , A61K45/06 , G01N33/6863 , G01N2500/10 , Y10S514/825 , Y10S514/826 , Y10S514/863 , Y10S514/866 , Y10S514/958 , A61K2300/00
摘要： The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.
摘要翻译： 本发明的特征在于通过给予患者（i）三环类抗抑郁药（例如阿莫沙平）治疗患有炎性病症的患者的方法; 和（ii）皮质类固醇（例如强的松龙），其量以足以减少或抑制炎症的量彼此同时或者在14天内。
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8.发明申请Combinations for the treatment of immunoinflammatory disorders and proliferative skin diseases 审中-公开用于治疗免疫炎症疾病和增殖性皮肤疾病的组合公开(公告)号：US20050159485A1
公开(公告)日：2005-07-21
申请号：US10500544
申请日：2003-01-02
申请人： Edward Jost-Price , Palaniyandi Manivasakam , Grant Zimmermann , Nicole Hurst , Jason Fong , Curtis Keith , Alexis Borisy
发明人： Edward Jost-Price , Palaniyandi Manivasakam , Grant Zimmermann , Nicole Hurst , Jason Fong , Curtis Keith , Alexis Borisy
IPC分类号： A61K31/07 , A61K31/203 , A61K31/47 , A61K31/557 , A61K45/06
CPC分类号： A61K45/06 , A61K31/07 , A61K31/203 , A61K31/47 , A61K31/557 , A61K2300/00
摘要： The invention features a method for treating a patient who has an immunoinflammatory disorder or a proliferative skin disease, or is at risk for developing an immunoinflammatory disorder or a proliferative skin disease, by administering to the patient a prostaglandin and a retinoid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammatory or dermal/epidermal proliferation.
摘要翻译： 本发明的特征在于一种治疗患有免疫炎性疾病或增殖性皮肤疾病或有发展免疫炎性疾病或增殖性皮肤疾病的危险的患者的方法，通过同时或在14天内向患者施用前列腺素和类视黄醇 以足以减少或抑制免疫炎症或皮肤/表皮增殖的量。
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公开(公告)号：US20060100181A1
公开(公告)日：2006-05-11
申请号：US10513237
申请日：2003-05-02
申请人： Edward Jost-Price , Palaniyandi Manivasakam , Grant Zimmermann , Jason Fong , Nicole Hurst , Benjamin Auspitz , M Nichols , Curtis Keith
发明人： Edward Jost-Price , Palaniyandi Manivasakam , Grant Zimmermann , Jason Fong , Nicole Hurst , Benjamin Auspitz , M Nichols , Curtis Keith
IPC分类号： A61K31/573 , A61K31/557
CPC分类号： A61K31/557 , A61K31/56 , A61K31/573 , A61K45/06 , A61K2300/00
摘要： The invention features methods and compositions for the treatment of inflammatory skin conditions.
摘要翻译： 本发明的特征在于用于治疗炎性皮肤病症的方法和组合物。
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公开(公告)号：US20060148770A1
公开(公告)日：2006-07-06
申请号：US10517639
申请日：2003-06-05
申请人： Jason Fong , Edward Jost-Price , Curtis Keith , Palaniyandi Manivasakam , Grant Zimmermann , Robyn Sackeyfio , Grant Zimmermann
发明人： Jason Fong , Edward Jost-Price , Curtis Keith , Palaniyandi Manivasakam , Grant Zimmermann , Robyn Sackeyfio , Grant Zimmermann
IPC分类号： A61K31/573 , A61K31/496
CPC分类号： A61K31/496 , A61K31/4164 , A61K31/4196 , A61K31/56 , A61K31/573 , A61K2300/00
摘要： The invention features a method for treating a patient diagnosed with rheumatoid arthitis by systemically administering an azole and a steroid to the patient. The invention also features a pharmaceutical composition containing an azole and a steroid for the treatment of rheumatoid arthritis.
摘要翻译： 本发明的特征在于通过向患者全身施用唑和类固醇来治疗诊断为类风湿关节炎的患者的方法。 本发明还特征在于含有用于治疗类风湿性关节炎的唑类和类固醇的药物组合物。
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