公开(公告)号：US5456706A

公开(公告)日：1995-10-10

申请号：US177293

申请日：1994-01-04

申请人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

发明人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

IPC分类号： A61N1/05 ,  A61N1/39

CPC分类号： A61N1/0563 ,  A61N1/3956

摘要： A lead for use with an implantable cardioverter/defibrillator system is disclosed. In the preferred embodiment, the lead combines a right ventricular endocardial electrode, a superior vena cava electrode and one or more atrial sensing electrodes on a single catheter lead. The distal end of the lead is transvenously implanted, typically through an incision in the cephalic or subclavian vein. The proximal end of the lead is then tunneled below the fascia to the location of the pulse generator. Ventricular sensing and/or pacing electrode(s) may also be included at the distal end of the combined lead to provide ventricular intracardiac electrogram sensing and bradycardia pacing.

摘要翻译： 公开了一种用于植入式心律转复/除颤器系统的引导件。 在优选实施例中，引线将单个导管引线上的右心室心内膜电极，上腔静脉电极和一个或多个心房感测电极组合。 导管的远端经常植入，通常通过头部或锁骨下静脉中的切口。 引线的近端然后在筋膜下方隧道穿过脉冲发生器的位置。 心室感应和/或起搏电极也可以包括在组合导联的远端，以提供心室心电图检测和心动过缓起搏。

公开(公告)号：US4880005A

公开(公告)日：1989-11-14

申请号：US198614

申请日：1988-05-23

申请人： Benjamin D. Pless ,  Michael B. Sweeney

发明人： Benjamin D. Pless ,  Michael B. Sweeney

IPC分类号： A61N1/362

CPC分类号： A61N1/3621

摘要： A heart pacemaker detects pace-terminable tachycardia conditions in the atrium of the heart in accordance with selected high rate, rate stability, sudden onset and sustained high rate criteria. When a pace-terminable tachycardia is detected, programmed treatment modalities are applied to attempt to terminate the tachycardia. The tachycardia is treated by applying timed bursts of electrical pulses in formats defined by programmed primary and secondary treatment modalities. The primary and secondary treatments may be applied in an order which is dependent upon the prior successful treatment of similar tachycardias. The pacemaker may also utilize remembered treatment values which were successfully applied to treat similar tachycardias. The pacemaker may be programmed to restart the primary and secondary modes of treatment in the event that the modes initially failed to terminate a tachycardia. The pacemaker may also be programmed to limit the rate of burst pulses to avoid overstimulating the heart.

公开(公告)号：US4872459A

公开(公告)日：1989-10-10

申请号：US199998

申请日：1988-05-27

申请人： Benjamin D. Pless ,  Michael B. Sweeney

发明人： Benjamin D. Pless ,  Michael B. Sweeney

IPC分类号： A61N1/362

CPC分类号： A61N1/3621

摘要： A heart pacemaker detects pace-terminable tachycardia conditions in the atrium of the heart in accordance with selected high rate, rate stability, sudden onset and sustained high rate criteria. When a pace-terminable tachycardia is detected, programmed treatment modalities are applied to attempt to terminate the tachycardia. The tachycardia is treated by applying timed bursts of electrical pulses in formats defined by programmed primary and secondary treatment modalities. The primary and secondary treatments may be applied in an order which is dependent upon the prior successful treatment of similar tachycardias. The pacemaker may also utilize remembered treatment values which were successfully applied to treat similar tachycardias. The pacemaker may be programmed to restart the primary and secondary modes of treatment in the event that the modes initially failed to terminate a tachycardia. The pacemaker may also be programmed to limit the rate of burst pulses to avoid overstimulating the heart.

摘要翻译： 心脏起搏器根据选择的高速率，速率稳定性，突然发作和持续的高速率标准检测心脏心房中的起搏性心动过速状况。 当检测到起搏性心动过速时，应用程序化治疗方式来试图终止心动过速。 通过以编程的初级和次级治疗方式定义的格式施加电脉冲的定时脉冲来治疗心动过速。 主要和次要治疗可以以依赖于先前成功治疗类似的心动过速的顺序来施用。 起搏器还可以利用成功应用于治疗类似心动过速的记忆治疗值。 起搏器可能被编程为在模式最初未能终止心动过速的情况下重新启动主要和次要治疗模式。 起搏器也可以被编程以限制脉冲脉冲的频率以避免过度刺激心脏。

公开(公告)号：US20100009036A1

公开(公告)日：2010-01-14

申请号：US12374984

申请日：2007-07-26

申请人： Michael B. Sweeney

发明人： Michael B. Sweeney

IPC分类号： A23L1/30 ,  A23L1/10 ,  A23L1/302 ,  A23L1/00 ,  A23L3/00 ,  A23L1/20 ,  A23L1/305

CPC分类号： A61K36/738 ,  A23L7/101 ,  A23L7/148 ,  A23L7/196 ,  A23L11/03 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23V2002/00 ,  A61K31/047 ,  A61K31/10 ,  A61K31/205 ,  A61K31/519 ,  A61K31/555 ,  A61K31/675 ,  A61K31/737 ,  A61K33/06 ,  A61K36/16 ,  A61K36/185 ,  A61K36/258 ,  A61K36/28 ,  A61K36/77 ,  A61K36/82 ,  A23V2250/214 ,  A23V2200/15 ,  A23V2250/032 ,  A23V2250/2126 ,  A23V2250/302 ,  A23V2250/2122

摘要： This invention relates to a cold infusion process for fortifying corn and/or soybeans with one or more vitamin, non-vitamin, mineral, non-mineral, botanical, hormone, herb, neutraceutical, lipid, carbohydrate, amino acid, acid, salt, prebiotic, or probiotic functional additives. This invention also discloses an infused corn and/or soybean produced by the process of infusing the corn and/or soybean at a temperature of less than about 120° F. with a solution comprising water, a bridge initiator for acid salt bias, fortifying agent(s), and an acid in a quantity sufficient to reach a pH of about 3.65. Further, this invention provides a method for the infusion of a corn and/or soybean with at least one fortifying agent at approximately room temperature.

摘要翻译： 本发明涉及用于通过一种或多种维生素，非维生素，矿物，非矿物质，植物药，激素，草药，营养物质，脂质，碳水化合物，氨基酸，酸，盐， 益生元或益生菌功能添加剂。 本发明还公开了一种通过在小于约120°F的温度下将玉米和/或大豆浸入含有水的溶液，酸盐偏置的桥引发剂，强化剂的方法生产的输注玉米和/或大豆。 和足以达到约3.65的pH的量的酸。 此外，本发明提供了一种在大约室温下用至少一种强化剂灌注玉米和/或大豆的方法。

公开(公告)号：US5383908A

公开(公告)日：1995-01-24

申请号：US79069

申请日：1993-06-16

申请人： Michael B. Sweeney ,  Debra S. Echt

发明人： Michael B. Sweeney ,  Debra S. Echt

IPC分类号： A61N1/39

CPC分类号： A61N1/3918

摘要： An electrode configuration for an automatic implantable cardioverter/defibrillator system and method for its use are disclosed. The electrode configuration includes a first catheter transvenously positioned with a first electrode near the distal end of the catheter positioned in the right ventricle of a patient's heart. A second catheter carries second and third electrodes with the second electrode positioned in the superior vena cava region and the third electrode positioned in the left innominate vein. The second and third electrodes of the second catheter are connected together. A fourth electrode at the tip of the first catheter functions as a sensing/pacing electrode. A fifth electrode in the form of a subcutaneous patch is also electrically coupled to the second and third electrodes. The electrode arrangement can be positioned without the need for a thoracotomy. With the method of the invention, the automatic implantable cardioverter/defibrillator senses life-threatening arrhythmic conditions of the heart and issues at least one cardioverting or defibrillating pulse that is applied between the right ventricular electrode and the connected superior vena cava, innominate vein and subcutaneous patch electrodes. The invention provides preferential steering of discharge current through the septum between the right and left ventricles of the heart. The first catheter may also include a pacing tip.

摘要翻译： 公开了一种用于自动植入式心律转复除颤器系统的电极配置及其使用方法。 电极配置包括第一导管，其经常位于位于患者心脏右心室内的导管远端附近的第一电极。 第二导管携带第二电极和第三电极，其中第二电极位于上腔静脉区域中，第三电极位于左无名静脉。 第二导管的第二和第三电极连接在一起。 在第一导管的尖端处的第四电极用作感测/起搏电极。 形式为皮下贴片的第五电极也电耦合到第二和第三电极。 可以定位电极布置，而不需要开胸。 利用本发明的方法，自动植入式心律转复器/除颤器感测心脏的危及生命的心律失常状况，并且发出施加在右心室电极与连接的上腔静脉，无名静脉和皮下的至少一个心脏复律或去纤颤脉冲 贴片电极。 本发明提供了通过心脏右心室和左心室之间的隔膜的放电电流的优先转向。 第一导管还可以包括起搏尖。