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12 条记录 (耗时 0.032 秒)

    Cardiac defibrillation lead having defibrillation and atrial sensing electrodes
    1.
    发明授权
    Cardiac defibrillation lead having defibrillation and atrial sensing electrodes 失效
    心脏除颤导联具有除颤和心房感应电极

    公开(公告)号：US5456706A

    公开(公告)日：1995-10-10

    申请号：US177293

    申请日：1994-01-04

    申请人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

    发明人： Benjamin D. Pless ,  Drew A. Hoffmann ,  Michael B. Sweeney ,  M. Elizabeth Bush ,  Steven M. Mitchell

    IPC分类号： A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/0563 ,  A61N1/3956

    摘要： A lead for use with an implantable cardioverter/defibrillator system is disclosed. In the preferred embodiment, the lead combines a right ventricular endocardial electrode, a superior vena cava electrode and one or more atrial sensing electrodes on a single catheter lead. The distal end of the lead is transvenously implanted, typically through an incision in the cephalic or subclavian vein. The proximal end of the lead is then tunneled below the fascia to the location of the pulse generator. Ventricular sensing and/or pacing electrode(s) may also be included at the distal end of the combined lead to provide ventricular intracardiac electrogram sensing and bradycardia pacing.

    摘要翻译： 公开了一种用于植入式心律转复/除颤器系统的引导件。 在优选实施例中，引线将单个导管引线上的右心室心内膜电极，上腔静脉电极和一个或多个心房感测电极组合。 导管的远端经常植入，通常通过头部或锁骨下静脉中的切口。 引线的近端然后在筋膜下方隧道穿过脉冲发生器的位置。 心室感应和/或起搏电极也可以包括在组合导联的远端，以提供心室心电图检测和心动过缓起搏。

    Lead with septal defibrillation and pacing electrodes
    2.
    发明授权
    Lead with septal defibrillation and pacing electrodes 失效
    带隔膜除颤和起搏电极

    公开(公告)号：US5683447A

    公开(公告)日：1997-11-04

    申请号：US574802

    申请日：1995-12-19

    申请人： M. Elizabeth Bush ,  Eric S. Fain ,  Drew A. Hoffmann ,  Benjamin D. Pless

    发明人： M. Elizabeth Bush ,  Eric S. Fain ,  Drew A. Hoffmann ,  Benjamin D. Pless

    IPC分类号： A61N1/04 ,  A61N1/05

    CPC分类号： A61N1/0573 ,  A61N1/056 ,  A61N1/0563

    摘要： A lead system for use with an implantable pacemaker/cardioverter/defibrillator. The lead system includes a securable pace/sense electrode positioned between the distal tip of the lead and the tricuspid valve. The distal tip of the lead is positioned at the apex of the right ventricle and may or may not be secured there by a second fixation means such as a screw tip or tines. The securable pace/sense electrode allows the defibrillation electrode to be accurately positioned by the patient's surgeon and maintained in intimate contact with the septum wall of the patient's heart, thereby reducing defibrillation thresholds; it provides a sense signal from the region of the His bundle or AV node, which can be used with other electrodes to distinguish between various arrhythmias; and it provides more physiologic pacing leading to greater cardiac output.

    摘要翻译： 用于植入式心脏起搏器/心律转复除颤器的牵引系统。 引导系统包括位于引线的远端和三尖瓣之间的可固定速度/感测电极。 引线的远端位于右心室的顶点处，并且可以通过第二固定装置（例如螺钉尖端或尖齿）固定或不固定。 可靠的速度/感测电极允许除颤电极由患者的外科医生精确定位，并与患者心脏的隔膜壁保持紧密接触，从而减少除颤阈值; 它从His束或AV节点的区域提供感测信号，其可以与其他电极一起使用以区分各种心律失常; 并且它提供更多的生理起搏导致更大的心输出量。

    Lead having an integrated defibrillation/sensing electrode
    3.
    发明授权
    Lead having an integrated defibrillation/sensing electrode 失效
    具有综合除颤/感测电极的引线

    公开(公告)号：US5534022A

    公开(公告)日：1996-07-09

    申请号：US343293

    申请日：1994-11-22

    申请人： Drew A. Hoffmann ,  M. Elizabeth Bush

    发明人： Drew A. Hoffmann ,  M. Elizabeth Bush

    IPC分类号： A61N1/04 ,  A61N1/05

    CPC分类号： A61N1/0563

    摘要： An implantable defibrillator lead having an improved integrated bipolar defibrillation electrode is disclosed. The defibrillation electrode is electrically connected to the lead conductor at the distal end, and has an increased surface area portion at the distal end, for bipolar sensing with a right ventricular pacing electrode.

    摘要翻译： 公开了具有改进的集成双极除颤电极的可植入除颤器引线。 除颤电极在远端电连接到引线导体，并且在远端具有增加的表面积部分，用于与右心室起搏电极进行双极感测。

    Implantable cardiac electrode with rate controlled drug delivery
    4.
    发明授权
    Implantable cardiac electrode with rate controlled drug delivery 失效
    具有速率控制药物递送的可植入心脏电极

    公开(公告)号：US5496360A

    公开(公告)日：1996-03-05

    申请号：US226594

    申请日：1994-04-12

    申请人： Drew A. Hoffmann ,  M. Elizabeth Bush

    发明人： Drew A. Hoffmann ,  M. Elizabeth Bush

    IPC分类号： A61N1/05 ,  A61N1/04

    CPC分类号： A61N1/0568

    摘要： A body implantable electrode with rate controlled drug delivery is disclosed. A body implantable lead is provided for the delivery of stimulation energy to a desired body site includes a drug dispenser carried by the lead which retains a drug to be dispensed at least adjacent the desired body stimulation site. The drug may be one which is intended to counter thrombus formation, fibrosis, inflammation or arrhythmias, for example. The drug may be in liquid or powder form retained in a reservoir carried by the lead. The reservoir is formed as a pump which controls dispensing of the drug using a fluid drawing agent such as a salt.

    摘要翻译： 公开了具有速率控制的药物递送的身体可植入电极。 提供用于将刺激能量递送到期望的身体部位的身体可植入引线，包括由铅保持的药物分配器，所述药剂分配器至少在所需的身体刺激部位附近保持待分配的药物。 药物可以是例如旨在抵抗血栓形成，纤维化，炎症或心律失常的药物。 药物可以是液体或粉末形式，保留在由铅携带的储存器中。 储存器形成为泵，其使用诸如盐的流体抽取剂来控制药物的分配。

    Method of using electrical energy to produce temporary conduction block for defibrillation and cardioversion
    5.
    发明授权
    Method of using electrical energy to produce temporary conduction block for defibrillation and cardioversion 失效

    公开(公告)号：US06431173B1

    公开(公告)日：2002-08-13

    申请号：US09487222

    申请日：2000-01-19

    申请人： Drew A. Hoffmann

    发明人： Drew A. Hoffmann

    IPC分类号： H61N139

    CPC分类号： A61N1/3956 ,  A61N1/395

    摘要： A method for treating arrhythmias which includes the steps of detecting an arrhythmia, and, in response to detection of the arrhythmia, delivering electrical energy to a targeted part of myocardial tissue in such a manner as to create a transient conduction block in the targeted part of the myocardial tissue without causing permanent damage to the targeted part of the myocardial tissue. The electrical energy can be continuous or pulsed RF, or continuous or pulsed DC. The detected arrhythmia can be atrial fibrillation, atrial flutter, ventricular fibrillation, or other type of arrhythmia. The targeted part of the myocardial tissue constitutes a critical part of the reentrant pathway or reentrant circuit required to sustain the detected arrhythmia. The electrical energy is preferably delivered via a catheter-based electrode which is in direct contact with the targeted part of the myocardial tissue, for either a prescribed period of time or until the arrhythmia is no longer detected (i.e., is terminated). In the former case, the prescribed period of time can be either sufficient to ensure that the arrhythmia can no longer be sustained, or sufficient to ensure that the arrhythmia is organized well enough to be terminated with additional low energy cardioversion/defibrillation therapy (such as a biphasic shock or pulse train). In a first alternative embodiment of the method of the present invention, a shock (or other form of cardioversion or defibrillation therapy) can be delivered, and then, if necessary (e.g., if it is detected that the fibrillation has not been terminated), electrical energy can be delivered to a targeted part of the myocardial tissue in order to create a transient conduction block in the targeted part of the myocardial tissue. In a second alternative embodiment of the method of the present invention, electrical energy is delivered to a targeted part of the myocardial tissue in order to create a first transient conduction block in the targeted part of the myocardial tissue, then a shock (or other form of cardioversion or defibrillation therapy) can be delivered, and then, if necessary (e.g., if it is detected that the fibrillation has not been terminated), electrical energy can again be delivered to the targeted part of the myocardial tissue in order to create a second transient conduction block in the targeted part of the myocardial tissue. The method is preferably carried out by using an automatic implantable defibrillator.

    Explantable lead
    6.
    发明授权
    Explantable lead 失效
    可引导铅

    公开(公告)号：US5902329A

    公开(公告)日：1999-05-11

    申请号：US970492

    申请日：1997-11-14

    申请人： Drew A. Hoffmann ,  Dean F. Carson

    发明人： Drew A. Hoffmann ,  Dean F. Carson

    IPC分类号： A61K47/48 ,  A61L31/10 ,  A61L31/14 ,  A61N1/05

    CPC分类号： A61L31/145 ,  A61K47/48992 ,  A61L31/10

    摘要： An extractable lead and method for chronic blood contacting use. The new lead contains a hydrogel coating having a thickness increase greater than 10% when hydrated. A thick coating is used to provide a shear layer so that the coating tears during extraction, either at the coating/lead interface, between layers of the coating itself, or at the coating/tissue interface. Furthermore, because of the flexibility of such a thick coating, contracture of any fibrous capsule that may have formed is not a problem during extraction, since instead of contracting onto the lead, it contracts onto the flexible coating which can be extracted out of the tight capsule.

    摘要翻译： 用于慢性血液接触使用的可提取铅和方法。 新的铅含有当水合时厚度增加大于10％的水凝胶涂层。 使用厚涂层来提供剪切层，使得涂层在涂层/引线界面处，在涂层本身的层之间或在涂层/组织界面处提取期间撕裂。 此外，由于这种厚涂层的灵活性，可能形成的任何纤维胶囊的挛缩在提取过程中不是问题，因为它不是收缩到铅上，而是收缩到柔性涂层上，可以从紧的 胶囊。

    Co-radial, multi-polar coiled cable lead and method for making the same
    8.
    发明授权
    Co-radial, multi-polar coiled cable lead and method for making the same 失效
    同径径，多极线圈电缆引线及其制作方法

    公开(公告)号：US5845396A

    公开(公告)日：1998-12-08

    申请号：US767912

    申请日：1996-12-17

    申请人： Peter A. Altman ,  Drew A. Hoffmann

    发明人： Peter A. Altman ,  Drew A. Hoffmann

    IPC分类号： A61N1/05 ,  H01B7/04 ,  H01B13/008 ,  H01R43/28

    CPC分类号： H01B13/008 ,  A61N1/056 ,  A61N1/0563 ,  Y10T29/49218 ,  Y10T29/4922 ,  Y10T29/49224

    摘要： A method for making a co-radial, multi-polar coiled cable lead. The method includes the steps of attaching a first end of a coated cable to a mandrel using a first end fixture. The coated cable comprises one or more cable strands, where each strand is made from one or more filaments. After the first end of the cable is attached to the mandrel, the cable is wound around the mandrel to form a coiled cable. A second end of the coiled cable is then attached to the mandrel using a second end fixture to retain the coiled cable under tension. Second stage processing is then performed on the coiled cable so that the end fixtures may be subsequently removed from the coiled cable without the coiled cable unwinding. After the second stage processing is complete, the coiled cable can be used in the manufacture of an implantable lead.

    摘要翻译： 一种制造同向径向多极线圈电缆引线的方法。 该方法包括以下步骤：使用第一端部固定件将涂覆的电缆的第一端附接到心轴。 涂覆的电缆包括一个或多个电缆股线，其中每条股线由一根或多根细丝制成。 在电缆的第一端附接到心轴之后，电缆缠绕在心轴上以形成线圈电缆。 螺旋线缆的第二端然后使用第二端部固定件附接到心轴，以将卷绕的缆线保持在张力下。 然后在线圈电缆上执行第二阶段处理，使得可以随后从线圈电缆中取出端部固定装置，而不用卷绕的电缆展开。 在第二阶段处理完成之后，线圈电缆可用于可植入引线的制造。