摘要:
The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
摘要:
The invention relates to the compounds of formula (I): in which R1, R2, R3, R4, Q and Z are as defined in the specification. The invention also relates to the pharmaceutical compositions containing these compounds.
摘要:
The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification.The compounds are modulators of the estrogen receptors.
摘要:
The present invention relates to compounds of formula (I): in which R1, R2, R3, X, Y and A are as defined in the specification. The compounds are modulators of the estrogen receptors.
摘要:
The invention relates to the compounds of formula (I): in which R1, R2, R3, R4, Q and Z are as defined in the specification. The invention also relates to the pharmaceutical compositions containing these compounds.
摘要:
The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in claim 1, to the preparation thereof and to the use thereof as medicaments. The compounds (I) are inhibitors of steroid sulfatase and are used for the treatment of cancer.
摘要:
The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in Claim 1, to the preparation thereof and to the use thereof as medicaments. The compounds (I) are inhibitors of steroid sulfatase and are used for the treatment of cancer.
摘要:
New .alpha.-phenoxy-alkanols represented by the general formula ##STR1## in which R.sup.1 and R.sub.2, which may be identical or different, represent a hydrogen atom or the CH.sub.3 radical, and their stereoisomers of R,S conformation when they contain at least one asymmetric carbon.
摘要:
Preparation process for 3,4-disubstituted dinitroanilines of formula ##STR1## in which, R.sub.1 and R.sub.2, which are identical to or different from one another, represent a hydrogen atom, a C.sub.1 to C.sub.6 saturated, linear or branched alkyl radical, a C.sub.2 to C.sub.6 linear or branched alkylene radical, a cyclopropyl radical or a chloroethyl radical,R.sub.3 and R.sub.4, which are identical to or different from one another are chosen from the group containing the chlorine atom, the amino group, the C.sub.1 to C.sub.3 lower alkyl radicals and the trifluoromethyl radical,comprising successively a dinitration stage of a 3,4-disubstituted phenol, an alkylation stage of the dinitrated derivative thus obtained and an amination stage of the 3,4-disubstituted 2,6-dinitro-alkoxybenzene thus obtained.