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公开(公告)号：US20230313107A1
公开(公告)日：2023-10-05
申请号：US18147356
申请日：2022-12-28
Applicant: BERKELEY LIGHTS, INC.
Inventor： Andrew W. McFarland , Peter J. Beemiller , Guido K. Stadler , Alexander J. Mastroianni , Joshua J. Cardiel Rivera , Darcy K. Kelly-Greene , Jonathan Cloud Dragon Hubbard , Natalie C. Marks , Long Van Le , Ke-Chih Lin
IPC: C12M1/00 , C12M3/06 , C12M3/00 , C12M1/34 , C12N5/0783
CPC classification number: C12M29/10 , C12M23/16 , C12M23/40 , C12M23/42 , C12M41/12 , C12M41/36 , C12N5/0636 , B01L2300/0883
Abstract: Cartridge for manufacturing a population of cells suitable for formulation as a cellular therapeutic are disclosed herein, along with systems for operating the cartridges and performing methods to generate the population of cells suitable for formulation as a cellular therapeutic. The population of cells suitable for formulation as a cellular therapeutic can be T-cells, including CAR T-cells. The systems and methods can be largely automated.
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公开(公告)号：US20220325240A1
公开(公告)日：2022-10-13
申请号：US17574459
申请日：2022-01-12
Applicant: Berkeley Lights, Inc.
Inventor： Andrew W. McFarland , Peter J. Beemiller , Guido K. Stadler , Alexander J. Mastroianni , Joshua J. Cardiel Rivera , Darcy K. Kelly-Greene , Jonathan Cloud Dragon Hubbard , Natalie C. Marks , Long Van Le , Ke-Chih Lin
Abstract: Cartridges for manufacturing a population of cells suitable for formulation as a cellular therapeutic are disclosed herein, along with systems and instruments for operating the cartridges and performing methods to generate the population of cells suitable for formulation as a cellular therapeutic. The population of cells suitable for formulation as a cellular therapeutic can be immunological cells, such as T lymphocytes, including endogenous T cells (ETCs), tumor infiltrating lymphocytes (TILs), CAR T-cells, TCR engineered T-cells, or otherwise engineered T-cells. The systems and methods can be largely automated.
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