公开(公告)号：US20070293766A1

公开(公告)日：2007-12-20

申请号：US11574163

申请日：2005-08-24

申请人： Bernardus Bakker ,  Gerald Lucassen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Robert Hendriks ,  Frank Schuurmans

发明人： Bernardus Bakker ,  Gerald Lucassen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Robert Hendriks ,  Frank Schuurmans

IPC分类号： G01J3/28

CPC分类号： A61B5/489 ,  A61B5/0059 ,  A61B2562/0238 ,  G01J3/36 ,  G01J3/42 ,  G01N21/31 ,  G01N21/35 ,  G01N21/59

摘要： The present invention provides a spectroscopic system and a transmission based imaging system for a spectroscopic system as well as a probe head for a transmission based imaging system for a spectroscopic system and a corresponding transmission based imaging method. The spectroscopic system is preferably applicable to in vivo noninvasive blood analysis. Transmission based imaging makes use of a transmitted portion of an imaging or monitoring beam that has been transmitted through biological tissue. By means of transmission based imaging, a contrast decreasing impact of scattered radiation can be effectively reduced. Additionally, by arranging the imaging light source opposite to an objective lens of the spectroscopic system, unintended propagation of spectroscopic excitation radiation into free space can be effectively prevented.

摘要翻译： 本发明提供了一种用于分光系统的光谱系统和基于透射的成像系统以及用于分光系统的基于透射的成像系统和相应的基于透射的成像方法的探针头。 光谱系统优选适用于体内非侵入性血液分析。 基于传输的成像利用已经通过生物组织传输的成像或监视光束的透射部分。 通过基于传输的成像，可以有效降低散射辐射的对比度减小的影响。 此外，通过将成像光源与分光系统的物镜相对设置，可以有效地防止光谱激发辐射的非预期传播进入自由空间。

公开(公告)号：US20070070328A1

公开(公告)日：2007-03-29

申请号：US10595358

申请日：2004-10-15

申请人： Wouter Rensen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Bernardus Bakker ,  Gerhardus Lucassen ,  Teunis Tukker

发明人： Wouter Rensen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Bernardus Bakker ,  Gerhardus Lucassen ,  Teunis Tukker

IPC分类号： G01N33/48 ,  A61B5/00

CPC分类号： A61B5/0059 ,  A61B5/0068 ,  A61B5/489

摘要： The present invention enables to determine the property of a fluid, such as for the purposes of in vivo blood analysis. First the position of a volume of interest through which the fluid flows is determined by means of an optical detection step by making use of an objective. Preferably the optical detection step is an imaging step. Next the objective is moved to bring the focal point of the objective to the volume of interest. In this position an optical spectroscopic step is performed. This has the advantage that the measurement beam for performing the optical spectroscopy travels along the optical axis for optimum efficiency.

摘要翻译： 本发明能够确定流体的性质，例如用于体内血液分析的目的。 首先，通过利用目标的光学检测步骤来确定流体流过的感兴趣体积的位置。 优选地，光学检测步骤是成像步骤。 接下来，将目标转移到目标的焦点。 在该位置，进行光学分光步骤。 这具有以下优点：用于执行光学光谱的测量光束沿着光轴行进以获得最佳效率。

公开(公告)号：US20070213609A1

公开(公告)日：2007-09-13

申请号：US11568363

申请日：2005-02-14

申请人： Gerhardus Lucassen ,  Wouter Rensen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Bernardus Bakker

发明人： Gerhardus Lucassen ,  Wouter Rensen ,  Michael Van Beek ,  Marjolein Van Der Voort ,  Bernardus Bakker

IPC分类号： A61B5/1455 ,  G01J3/42

CPC分类号： A61B5/0059 ,  A61B5/489 ,  A61B2562/0242

摘要： The present invention provides a spectroscopic system for determining a property of a fluid flowing through a volume of interest underneath the surface of the skin of a patient. The spectroscopic system comprises a probe head that has at least an objective for directing an excitation beam into the volume of interest and for collecting return radiation. The spectroscopic system has further a base station having at least a spectroscopic analysis unit and a power supply. The system makes use of a beam combination unit, a filter unit and a focusing unit for combining and separating a variety of different optical signals and for precisely positioning the optical signals inside the volume of interest. The beam combination unit, the filter unit and the focusing unit can be variably implemented inside the probe head or inside the base station depending on a specific applications of the spectroscopic system, thereby allowing for a flexible and compact design of the probe head.

摘要翻译： 本发明提供了一种用于确定流过患者皮肤表面下方的感兴趣体积的流体的性质的光谱系统。 分光系统包括探头，该探头至少具有将激发光束引导到感兴趣体积中并用于收集返回辐射的目的。 光谱系统还具有至少具有光谱分析单元和电源的基站。 该系统利用光束组合单元，滤光器单元和聚焦单元，用于组合和分离各种不同的光信号，并将光信号精确地定位在感兴趣的体积内。 根据分光系统的具体应用，光束组合单元，滤光器单元和聚焦单元可以可变地实现在探头内部或基站内部，从而允许探头的灵活且紧凑的设计。

公开(公告)号：US20060217586A1

公开(公告)日：2006-09-28

申请号：US10538620

申请日：2003-11-18

申请人： Robert Van Hal ,  Bernardus Bakker ,  Michiel Roersma ,  Peter Bjerring

发明人： Robert Van Hal ,  Bernardus Bakker ,  Michiel Roersma ,  Peter Bjerring

IPC分类号： A61N5/00 ,  A61H33/00

CPC分类号： A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/1807

摘要： The invention relates to a device (1) for treating human skin by means of radiation. The device has a housing (5) with a radiation exit opening (13), a radiation source (9) which is accommodated in the housing, and a radiation path (15) between the radiation source and the radiation exit opening. A radiation filter (17) is provided in the radiation path. According to the invention the radiation filter (17) comprises water (23) which is in solid state at least during an initial phase of operation of the device (1). The water in solid state has an optical transmission spectrum which corresponds to the optical transmission spectrum of water in liquid state as present in the skin. As a result the water in solid state acts as an ideal filter for the IR light and near IR light, which would otherwise be absorbed by the water in the skin and cause unwanted heating of the skin. An additional advantage of the water in solid state is its relatively high heat absorbing capacity and its ability to cool the skin in case of direct thermal contact with the skin. In a particular embodiment the device (1) is an epilator for the removal of hairs from the human skin, the radiation source (9) being a flash lamp which generates light pulses having a high energy density and a broad optical spectrum.

摘要翻译： 本发明涉及一种用于通过辐射处理人体皮肤的装置（1）。 该装置具有壳体（5），其具有辐射出口（13），容纳在壳体中的辐射源（9）和辐射源与辐射出口之间的辐射路径（15）。 辐射过滤器（17）设置在辐射路径中。 根据本发明，辐射过滤器（17）包括至少在设备（1）的初始操作阶段期间处于固态的水（23）。 固态的水具有对应于存在于皮肤中的处于液态的水的光透射光谱的光透射光谱。 因此，固态的水作为IR光和近红外光的理想过滤器，否则会被皮肤中的水吸收并引起皮肤不必要的加热。 固体水中的另一个优点是其相对较高的吸热能力以及在与皮肤直接热接触的情况下冷却皮肤的能力。 在特定实施例中，装置（1）是用于从人体皮肤去除毛发的脱毛器，所述辐射源（9）是产生具有高能量密度和宽光谱的光脉冲的闪光灯。

公开(公告)号：US20060241573A1

公开(公告)日：2006-10-26

申请号：US10566199

申请日：2004-07-20

申请人： Michiel Roersma ,  Bernardus Bakker

发明人： Michiel Roersma ,  Bernardus Bakker

IPC分类号： A61B18/18

CPC分类号： A61N5/0616 ,  A61B18/20 ,  A61B18/203 ,  A61B2018/00452 ,  A61B2018/00636 ,  A61B2090/064

摘要： The present invention relates to a device for administering electromagnetic radiation to human tissue, in particular light to skin. The device comprises a treatment head with a recess (10) in which the light is emitted and in which the air pressure may be decreased by a pump (11). The device also comprises a pressure gauge (8) for measuring the pressure in the recess (10). Above a certain threshold value the device will not function, because this indicates an incorrect positioning of the device on the skin, which might cause harm to persons. By providing the pressure gauge (8), an operator may determine whether the positioning of the treatment head is correct. The device is advantageously automated in that the pressure gauge (8) is connected to control means (5) for controlling the source (3) of radiation.

摘要翻译： 本发明涉及一种用于向人体组织，特别是对皮肤照射电磁辐射的装置。 该装置包括具有凹部（10）的处理头，其中发射光，并且其中空气压力可以通过泵（11）减小。 该装置还包括用于测量凹部（10）中的压力的​​压力计（8）。 超过某个阈值时，设备将不起作用，因为这表示设备在皮肤上的定位不正确，可能会对人造成伤害。 通过提供压力计（8），操作者可以确定治疗头的定位是否正确。 该装置有利地是自动化的，因为压力计（8）连接到用于控制辐射源（3）的控制装置（5）。