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公开(公告)号:US06251645B1
公开(公告)日:2001-06-26
申请号:US09338546
申请日:1999-06-23
IPC分类号: C12N900
CPC分类号: C12Q1/6886 , A61K38/00 , C07K14/47 , C12N9/90 , C12Q1/68 , C12Q1/6823 , C12Q2600/156 , C12Q2521/301
摘要: The present invention relates to the identification and molecular-biological and biochemical characterization of novel DEAH-box proteins which show structural similarity with other known helicases. The invention also relates to DNA sequences encoding such proteins. It is demonstrated that such proteins bind ATP and nucleic acid and possess helicase and ATPase activities. This invention further relates to processes for preparation of such proteins and their use in pharmacologically relevant test systems and therapeutic applications.
摘要翻译: 本发明涉及与其他已知的解旋酶显示结构相似性的新型DEAH盒蛋白的鉴定和分子生物学和生物化学表征。 本发明还涉及编码这种蛋白质的DNA序列。 证明这些蛋白质结合ATP和核酸并具有解旋酶和ATP酶活性。 本发明还涉及制备这些蛋白质的方法及其在药理学相关的测试系统和治疗应用中的用途。
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公开(公告)号:US06403299B1
公开(公告)日:2002-06-11
申请号:US09659084
申请日:2000-09-11
IPC分类号: C12Q100
CPC分类号: C12Q1/6886 , A61K38/00 , C07K14/47 , C12N9/90 , C12Q1/68 , C12Q1/6823 , C12Q2600/156 , C12Q2521/301
摘要: The present invention relates to the identification and molecular-biological and biochemical characterization of novel DEAH-box proteins which show structural similarity with other known helicases. The invention also relates to DNA sequences encoding such proteins. It is demonstrated that such proteins bind ATP and nucleic acid and possess helicase and ATPase activities. This invention further relates to processes for preparation of such proteins and their use in pharmacologically relevant test systems and therapeutic applications.
摘要翻译: 本发明涉及与其他已知的解旋酶显示结构相似性的新型DEAH盒蛋白的鉴定和分子生物学和生物化学表征。 本发明还涉及编码这种蛋白质的DNA序列。 证明这些蛋白质结合ATP和核酸并具有解旋酶和ATP酶活性。 本发明还涉及制备这些蛋白质的方法及其在药理学相关的测试系统和治疗应用中的用途。
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公开(公告)号:US5942429A
公开(公告)日:1999-08-24
申请号:US760075
申请日:1996-12-04
IPC分类号: C12N15/09 , A61K38/00 , C07K14/00 , C07K14/47 , C12N5/10 , C12N9/90 , C12N15/55 , C12Q1/68 , C12N9/16 , C07H21/04
CPC分类号: C12Q1/6886 , C07K14/47 , C12N9/90 , C12Q1/68 , C12Q1/6823 , A61K38/00 , C12Q2600/156
摘要: The present invention relates to the identification and molecular-biological and biochemical characterization of novel DEAH-box proteins which show structural similarity with other known helicases. The invention also relates to DNA sequences encoding such proteins. It is demonstrated that such proteins bind ATP and nucleic acid and possess helicase and ATPase activities. This invention further relates to processes for preparation of such proteins and their use in pharmacologically relevant test systems and therapeutic applications.
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公开(公告)号:US20050202476A1
公开(公告)日:2005-09-15
申请号:US11038367
申请日:2005-01-18
申请人: Andrea Saettler , Claudia Jassoy , Regine Scholtyssek , Vera Maienschein , Silke Nieveler , Albrecht Weiss , Karl-Heinz Trebesius , Claudia Beimfohr , Wolfgang Ludwig , Richard Bamberg , Karl-Heinz Schleifer , Stefan Muellner , Ingrid Bergmaier
发明人: Andrea Saettler , Claudia Jassoy , Regine Scholtyssek , Vera Maienschein , Silke Nieveler , Albrecht Weiss , Karl-Heinz Trebesius , Claudia Beimfohr , Wolfgang Ludwig , Richard Bamberg , Karl-Heinz Schleifer , Stefan Muellner , Ingrid Bergmaier
IPC分类号: G01N33/53 , C12N15/09 , C12Q1/68 , G01N33/569
摘要: The invention relates kits for detecting microorganisms containing at least one oligonucleotide for at least one species or a group of species of microorganisms which occur on the skin and to methods using the kits according to the invention.
摘要翻译: 本发明涉及用于检测微生物的试剂盒,所述微生物含有至少一种在皮肤上发生的至少一种或一组微生物的寡核苷酸,以及使用本发明的试剂盒的方法。
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公开(公告)号:US20050202477A1
公开(公告)日:2005-09-15
申请号:US11039026
申请日:2005-01-18
申请人: Andrea Saettler , Claudia Jassoy , Regine Scholtyssek , Vera Maienschein , Silke Nieveler , Albrecht Weiss , Karl-Heinz Trebesius , Claudia Beimfohr , Wolfgang Ludwig , Richard Bamberg , Karl-Heinz Schleifer , Stefan Muellner , Ingrid Bergmaier
发明人: Andrea Saettler , Claudia Jassoy , Regine Scholtyssek , Vera Maienschein , Silke Nieveler , Albrecht Weiss , Karl-Heinz Trebesius , Claudia Beimfohr , Wolfgang Ludwig , Richard Bamberg , Karl-Heinz Schleifer , Stefan Muellner , Ingrid Bergmaier
摘要: The present invention describes oligonucleotides for detecting microorganisms, and processes and kits including the same.
摘要翻译: 本发明描述了用于检测微生物的寡核苷酸,以及包含其的工艺和试剂盒。
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