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公开(公告)号：US20080272309A1
公开(公告)日：2008-11-06
申请号：US11570900
申请日：2005-06-24
IPC分类号： G01J1/42
CPC分类号： G01T1/1648
摘要： The invention refers to X-ray devices, an X-ray detector and a method of correcting intensity signals. An X-ray detector then comprises for determining the intensity of X-rays, which comprise a proportion of primary radiation having an irradiation direction and a proportion of scattered radiation, at least a first sensor elements, which are each provided for converting the X-rays into first and second intensity signals, and a filter element, which is provided for decreasing the proportion of scattered radiation in the intensity of the X-rays, wherein the second sensor elements are arranged in irradiation direction behind the filter element and wherein the first sensor element fastened to the filter element is provided for determining the intensity of the X-rays before leaving the filter element. The proportion of the scattered radiation calculated from the measuring data of the first and second sensor elements is provided for correcting the second intensity signals for the following image generation.
摘要翻译： 本发明涉及X射线装置，X射线检测器和校正强度信号的方法。 然后，X射线检测器包括用于确定包括具有照射方向和散射辐射的比例的一次辐射的比例的X射线的强度，至少第一传感器元件，其被设置用于转换X射线， 射线成为第一和第二强度信号;以及滤波器元件，其设置用于减小X射线强度中的散射辐射的比例，其中第二传感器元件沿着过滤元件后面的照射方向排列，并且其中第一 固定在过滤元件上的传感器元件用于确定离开过滤元件之前的X射线的强度。 提供从第一和第二传感器元件的测量数据计算的散射辐射的比例，用于校正用于后续图像生成的第二强度信号。
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公开(公告)号：US09348067B2
公开(公告)日：2016-05-24
申请号：US13319196
申请日：2010-06-09
CPC分类号： G02B5/1857 , A61B6/484 , G21K2201/06 , G21K2207/005
摘要： The present invention relates to phase-contrast imaging which visualizes the phase information of coherent radiation passing a scanned object. Focused gratings are used which reduce the creation of trapezoid profile in a projection with a particular angle to the optical axis. A laser supported method is used in combination with a dedicating etching process for creating such focused grating structures.
摘要翻译： 本发明涉及相位成像，其可视化通过扫描对象的相干辐射的相位信息。 使用聚焦光栅，其减小了与光轴具有特定角度的投影中的梯形轮廓的产生。 激光支持的方法与用于产生这种聚焦光栅结构的专用蚀刻工艺组合使用。
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公开(公告)号：US20110079865A1
公开(公告)日：2011-04-07
申请号：US12996400
申请日：2009-06-09
IPC分类号： H01L31/0224 , H01L21/02
CPC分类号： G01T1/2928
摘要： The invention relates to a radiation detector (10), comprising an array of pixels (1), wherein each pixel (1) comprises a conversion layer of a semiconductor material (4) for converting incident radiation into electrical signals and wherein each pixel (1) is surrounded by a trench (3) that is at least partly filled with a barrier material that absorbs at least a part of photons generated by the incident radiation. The invention also relates to a method of manufacturing such a radiation detector (10).
摘要翻译： 本发明涉及一种包括像素阵列（1）的辐射检测器（10），其中每个像素（1）包括用于将入射辐射转换成电信号的半导体材料（4）的转换层，并且其中每个像素 ）由至少部分地填充有吸收入射辐射产生的光子的至少一部分的阻挡材料的沟槽（3）包围。 本发明还涉及一种制造这种辐射探测器（10）的方法。
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公开(公告)号：US09750465B2
公开(公告)日：2017-09-05
申请号：US13514312
申请日：2010-12-08
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4291 , A61B6/484 , A61B6/488 , A61B6/5241
摘要： The invention relates to the field of X-ray differential phase contrast imaging. For scanning large objects and for an improved contrast to noise ratio, an X-ray device (10) for imaging an object (18) is provided. The X-ray device (10) comprises an X-ray emitter arrangement (12) and an X-ray detector arrangement (14), wherein the X-ray emitter arrangement (14) is adapted to emit an X-ray beam (16) through the object (18) onto the X-ray detector arrangement (14). The X-ray beam (16) is at least partial spatial coherent and fan-shaped. The X-ray detector arrangement (14) comprises a phase grating (50) and an absorber grating (52). The X-ray detector arrangement (14) comprises an area detector (54) for detecting X-rays, wherein the X-ray device is adapted to generate image data from the detected X-rays and to extract phase information from the X-ray image data, the phase information relating to a phase shift of X-rays caused by the object (18). The object (18) has a region of interest (32) which is larger than a detection area of the X-ray detector (18) and the X-ray device (10) is adapted to generate image data of the region of interest (32) by moving the object (18) and the X-ray detector arrangement (14) relative to each other.
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公开(公告)号：US09599577B2
公开(公告)日：2017-03-21
申请号：US13818696
申请日：2011-08-30
CPC分类号： G01N23/04 , G21K1/025 , G21K2207/00 , H01J2235/068
摘要： The invention relates to a method and an imaging system (100) for generating X-ray images. The system (100) comprises at least one X-ray source, preferably an array of X-ray sources (101a-101d), and an X-ray detector (103) with an array of sensitive pixels (103a-103e). A collimator (102) is arranged between the X-ray source and the detector such that two openings (P) of the collimator (102) allow the passage of X-rays towards two neighboring pixels (103a-103e) while the region between said pixels is substantially shielded. This shielding of the usually insensitive regions between pixels reduces unnecessary X-ray exposure. A sufficiently large X-ray intensity can be achieved by using a plurality of small X-ray sources (101a-101d).
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公开(公告)号：US09084528B2
公开(公告)日：2015-07-21
申请号：US13514682
申请日：2010-12-03
CPC分类号： A61B6/00 , A61B6/4291 , A61B6/4441 , A61B6/484
摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.
摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。
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7.发明授权Apparatus for phase-contrast imaging comprising a displaceable X-ray detector element and method 有权包括可移位的X射线检测器元件和方法的用于相位对比成像的装置公开(公告)号：US09066649B2
公开(公告)日：2015-06-30
申请号：US13514383
申请日：2010-12-03
申请人： Ewald Roessl , Klaus Juergen Engel , Gereon Vogtmeier , Dieter Geller , Gerhard Martens , Sebastian Siegmund Schusser , Thomas Koehler
发明人： Ewald Roessl , Klaus Juergen Engel , Gereon Vogtmeier , Dieter Geller , Gerhard Martens , Sebastian Siegmund Schusser , Thomas Koehler
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4021 , A61B6/4092 , A61B6/4291 , A61B6/484
摘要： An X-ray image acquisition apparatus employing phase-contrast imaging with enlarged field of view includes an X-ray source, an X-ray detector element having a detector size, a beam splitter grating and an analyzer grating. An object is arrangeable between the X-ray source and detector. The beam splitter grating and the analyzer grating are arrangeable between the X-ray source and detector. The X-ray source, the beam splitter grating, the analyzer grating and the X-ray detector are operatively coupled such that a phase-contrast image of the object is obtainable. The apparatus is configure to acquire a phase-contrast image having a field of view larger than the detector size. The X-ray detector element is displaceable where, by the displacement of the X-ray detector, a phase-contrast image of the enlarged field of view is obtainable.
摘要翻译： 采用具有放大视场的相位对比成像的X射线图像获取装置包括X射线源，具有检测器尺寸的X射线检测器元件，分束器光栅和分析器光栅。 X射线源和检测器之间可以配置一个物体。 分束器光栅和分析器光栅可以在X射线源和检测器之间布置。 X射线源，分束器光栅，分析器光栅和X射线检测器可操作地耦合，使得可以获得物体的相差图像。 该装置被配置为获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件可移动，其中通过X射线检测器的位移可以获得放大视场的相位对比图像。
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公开(公告)号：US08855265B2
公开(公告)日：2014-10-07
申请号：US13319527
申请日：2010-06-10
CPC分类号： A61B6/00 , A61B6/4092 , A61B6/4291 , A61B6/484 , G01N23/04 , G21K1/06 , G21K2207/005
摘要： The present invention generally refers to a correction method for grating-based X-ray differential phase contrast imaging (DPCI) as well as to an apparatus which can advantageously be applied in X-ray radiography and tomography for hard X-ray DPCI of a sample object or an anatomical region of interest to be scanned. More precisely, the proposed invention provides a suitable approach that helps to enhance the image quality of an acquired X-ray image which is affected by phase wrapping, e.g. in the resulting Moiré interference pattern of an emitted X-ray beam in the detector plane of a Talbot-Lau type interferometer after diffracting said X-ray beam at a phase-shifting beam splitter grating. This problem, which is further aggravated by noise in the obtained DPCI images, occurs if the phase between two adjacent pixels in the detected X-ray image varies by more than π radians and is effected by a line integration over the object's local phase gradient, which induces a phase offset error of π radians that leads to prominent line artifacts parallel to the direction of said line integration.
摘要翻译： 本发明总体上涉及一种用于基于光栅的X射线差分相位对比成像（DPCI）的校正方法以及可以有利地应用于X射线照相术和X射线成像的装置，用于样品的硬X射线DPCI 对象或要扫描的感兴趣的解剖区域。 更精确地，所提出的发明提供了一种合适的方法，其有助于增强受到相位包裹影响的获得的X射线图像的图像质量，例如， 在衍射在相移分束器光栅上的所述X射线束之后，在Talbot-Lau型干涉仪的检测器平面中产生的发射的X射线束的莫尔干涉图。 如果所检测的X射线图像中的两个相邻像素之间的相位变化多于＆pgr，则发生由获得的DPCI图像中的噪声进一步恶化的问题。 弧度并且通过对象的局部相位梯度上的线积分实现，其引起相位偏移误差＆pgr; 导致与所述线集成方向平行的突出的线条伪影的弧度。
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公开(公告)号：US20130156157A1
公开(公告)日：2013-06-20
申请号：US13818696
申请日：2011-08-30
IPC分类号： G01N23/04
CPC分类号： G01N23/04 , G21K1/025 , G21K2207/00 , H01J2235/068
摘要： The invention relates to a method and an imaging system (100) for generating X-ray 101a 101b 101c 101d images. The system (100) comprises at least one X-ray source, preferably an array of X-ray sources (101a-101d), and an X-ray detector (103) with an array of sensitive pixels (103a-103e). A collimator (102) is arranged between the X-ray source and the detector such that two openings (P) of the collimator (102) allow the passage of X-rays towards two neighboring pixels (103a-103e) while the region between said pixels is substantially shielded. This shielding of the usually insensitive regions between pixels reduces unnecessary X-ray exposure. A sufficiently large X-ray intensity can be achieved by using a plurality of small X-ray sources (101a-101d).
摘要翻译： 本发明涉及一种用于产生X射线101a 101b 101c 101d图像的方法和成像系统（100）。 系统（100）包括至少一个X射线源，优选X射线源阵列（101a-101d）和具有敏感像素阵列（103a-103e）的X射线检测器（103）。 准直器（102）布置在X射线源和检测器之间，使得准直器（102）的两个开口（P）允许X射线朝向两个相邻像素（103a-103e）通过，而所述准直器 像素基本被屏蔽。 像素之间通常不敏感区域的这种屏蔽减少了不必要的X射线曝光。 通过使用多个小的X射线源（101a-101d）可以获得足够大的X射线强度。
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公开(公告)号：US20120243658A1
公开(公告)日：2012-09-27
申请号：US13514682
申请日：2010-12-03
IPC分类号： G01N23/04
CPC分类号： A61B6/00 , A61B6/4291 , A61B6/4441 , A61B6/484
摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.
摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。
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