-
公开(公告)号：US20110150915A1
公开(公告)日：2011-06-23
申请号：US12960287
申请日：2010-12-03
申请人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
发明人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
CPC分类号： A61K39/21 , A61K39/00 , A61K39/12 , C12N2740/16034
摘要： The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
-
公开(公告)号：US20090324631A1
公开(公告)日：2009-12-31
申请号：US11990222
申请日：2006-08-23
申请人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
发明人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
CPC分类号： A61K39/21 , A61K39/00 , A61K39/12 , C12N2740/16034
摘要： The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
摘要翻译： 本发明一般涉及免疫原性组合物（例如疫苗），特别涉及多价免疫原性组合物，例如多价HIV疫苗，以及使用它们的方法。 本发明还涉及使用遗传算法来产生适合于例如疫苗接种策略中使用的多价抗原组的方法。
-
3.发明授权公开(公告)号：US09011875B2
公开(公告)日：2015-04-21
申请号：US13399963
申请日：2012-02-17
申请人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
发明人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
CPC分类号： A61K39/21 , A61K39/00 , A61K39/12 , C12N2740/16034
摘要： The present invention relates to mosaic HIV-1 group M Gag sequences and to a composition comprising same.
摘要翻译： 本发明涉及镶嵌HIV-1组M Gag序列和涉及包含其的组合物。
-
4.发明授权Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins 有权包含人免疫缺陷病毒（HIV）镶嵌Nef蛋白的免疫原性组合物公开(公告)号：US08119140B2
公开(公告)日：2012-02-21
申请号：US11990222
申请日：2006-08-23
申请人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
发明人： Bette T. Korber , Simon Perkins , Tanmoy Bhattacharya , William M. Fischer , James Theiler , Norman Letvin , Barton F. Haynes , Beatrice H. Hahn , Karina Yusim , Carla Kuiken
IPC分类号： A61K39/21
CPC分类号： A61K39/21 , A61K39/00 , A61K39/12 , C12N2740/16034
摘要： The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
摘要翻译： 本发明涉及马赛克进化枝M HIV-1 Nef多肽及其组合物。 本发明的多肽适用于诱导人体对HIV-1的免疫应答。
-
公开(公告)号：US20100104596A1
公开(公告)日：2010-04-29
申请号：US12450395
申请日：2008-03-27
申请人： Barton F. Haynes , Betle T. Korber , Beatrice H. Hahn , Tanmoy Bhattacharya , Gnana Ganakaram , Feng Gao , Ron Swanstrom , George Shaw , Barton F. Uaynes , Betle T Korber
发明人： Barton F. Haynes , Betle T. Korber , Beatrice H. Hahn , Tanmoy Bhattacharya , Gnana Ganakaram , Feng Gao , Ron Swanstrom , George Shaw , Barton F. Uaynes , Betle T Korber
CPC分类号： C07K14/005 , A61K39/12 , A61K39/21 , C12N2740/16122 , C12N2740/16134
摘要： The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to a method of inducing an immune response to HIV in a patient and to immunogens suitable for use in such a method. The invention also relates to diagnostic test kits and methods of using same.
摘要翻译： 本发明一般涉及人类免疫缺陷病毒（HIV），特别涉及在患者中诱导对HIV的免疫应答的方法以及适用于这种方法的免疫原。 本发明还涉及诊断测试试剂盒及其使用方法。
-
6.发明申请公开(公告)号：US20130110943A1
公开(公告)日：2013-05-02
申请号：US13287973
申请日：2011-11-02
IPC分类号： G06F15/16
CPC分类号： G06Q10/107
摘要： A centralized notification engine, which serves notifications from multiple applications, receives a request to register a notification from a particular application. Responsive to the request, the notification engine stores information that indicates a context of the notification. The notification engine determines whether the notification satisfies metadata-specified constraints. Responsive to determining that the notification satisfies the constraints, the notification engine selects, from a set of templates, a template that is associated with the notification's context. The notification engine applies the template to information specified by the notification. As a result, a populated template is produced.
摘要翻译： 用于从多个应用程序提供通知的集中式通知引擎接收从特定应用程序注册通知的请求。 响应于该请求，通知引擎存储指示该通知的上下文的信息。 通知引擎确定通知是否满足元数据指定的约束。 响应于确定通知满足约束，通知引擎从一组模板中选择与该通知的上下文相关联的模板。 通知引擎将模板应用于通知指定的信息。 结果，生成了填充的模板。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.04 秒)
