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公开(公告)号:US10206997B2
公开(公告)日:2019-02-19
申请号:US14356414
申请日:2011-11-10
申请人: Bin Wang , Shuang Geng
发明人: Bin Wang , Shuang Geng
IPC分类号: A61K31/195 , A61K31/20 , A61K31/30 , A61K31/7004 , A61K36/05 , A61K39/29 , A61K9/00 , A61K39/39 , C12N7/00 , A61K39/12 , A61K39/00
摘要: Provided herein is a vaccine that combines a vaccine facilitator and a DNA construct encoding an antigen to elicit antigen-specific antibody responses, wherein the vaccine facilitator is a Na/K pump inhibitor. Cellular entry of the DNA is accelerated as compared to other vaccines that do not contain the vaccine facilitator.
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公开(公告)号:US20150004194A1
公开(公告)日:2015-01-01
申请号:US14356414
申请日:2011-11-10
申请人: Bin Wang , Shuang Geng
发明人: Bin Wang , Shuang Geng
CPC分类号: A61K39/292 , A61K9/0009 , A61K39/12 , A61K39/39 , A61K2039/53 , A61K2039/54 , A61K2039/55505 , A61K2039/55511 , A61K2039/57 , A61K2039/572 , C12N7/00 , C12N2710/00034 , C12N2730/10134
摘要: Provided herein is a vaccine that combines a vaccine facilitator and a DNA construct encoding an antigen to elicit antigen-specific antibody responses, wherein the vaccine facilitator is a Na/K pump inhibitor. Cellular entry of the DNA is accelerated as compared to other vaccines that do not contain the vaccine facilitator.
摘要翻译: 本文提供了将疫苗促进剂和编码抗原的DNA构建体结合以引发抗原特异性抗体应答的疫苗,其中所述疫苗促进剂是Na / K泵抑制剂。 与不含疫苗促进剂的其他疫苗相比,DNA的细胞进入加速。
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