公开(公告)号：US08580541B2

公开(公告)日：2013-11-12

申请号：US12962366

申请日：2010-12-07

申请人： Bin Yang ,  Charles E. Wyman

发明人： Bin Yang ,  Charles E. Wyman

IPC分类号： C12P7/06 ,  C12P7/08 ,  C12P7/10 ,  C12P19/14 ,  C12P21/06 ,  C07K14/415 ,  C07K14/765

CPC分类号： C12P7/08 ,  C12P7/10 ,  C12P19/02 ,  Y02E50/16 ,  Y02E50/17

摘要： Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion and allows for the determination of optimized pretreatment conditions. Additionally, ethanol yields from a Simultaneous Saccharification and Fermentation process are improved 5-25% by treatment with a lignin-blocking polypeptide and/or protein.

摘要翻译： 公开了一种在木质纤维素生物质中转化纤维素的方法。 该方法提供高木质素固体的木质素阻断多肽和/或蛋白质处理。 该处理增强了纤维素转化中的纤维素酶可用性，并且允许确定优化的预处理条件。 此外，通过用木质素阻断多肽和/或蛋白质处理，来自同时糖化和发酵过程的乙醇产率提高了5-25％。

公开(公告)号：US07875444B2

公开(公告)日：2011-01-25

申请号：US11229817

申请日：2005-09-19

申请人： Bin Yang ,  Charles E. Wyman

发明人： Bin Yang ,  Charles E. Wyman

IPC分类号： C12P7/06 ,  C12P7/08 ,  C12P7/10 ,  C12P19/14 ,  C12P21/06 ,  C07K14/415 ,  C07K14/765

CPC分类号： C12P7/10 ,  C12P7/08 ,  C12P19/02 ,  Y02E50/16 ,  Y02E50/17

摘要： Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion and allows for the determination of optimized pretreatment conditions. Additionally, ethanol yields from a Simultaneous Saccharification and Fermentation process are improved 5-25% by treatment with a lignin-blocking polypeptide and/or protein. Thus, a more efficient and economical method of processing lignin containing biomass materials utilizes a polypeptide/protein treatment step that effectively blocks lignin binding of cellulase.

摘要翻译： 公开了一种在木质纤维素生物质中转化纤维素的方法。 该方法提供高木质素固体的木质素阻断多肽和/或蛋白质处理。 该处理增强了纤维素转化中的纤维素酶可用性，并且允许确定优化的预处理条件。 此外，通过用木质素阻断多肽和/或蛋白质处理，来自同时糖化和发酵过程的乙醇产率提高了5-25％。 因此，处理含木质素的生物质材料的更有效和经济的方法利用有效阻断木质素结合纤维素酶的多肽/蛋白质处理步骤。

公开(公告)号：US20110076725A1

公开(公告)日：2011-03-31

申请号：US12962366

申请日：2010-12-07

申请人： Bin Yang ,  Charles E. Wyman

发明人： Bin Yang ,  Charles E. Wyman

IPC分类号： C12P19/00 ,  C12P7/10

CPC分类号： C12P7/08 ,  C12P7/10 ,  C12P19/02 ,  Y02E50/16 ,  Y02E50/17

摘要： Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion and allows for the determination of optimized pretreatment conditions. Additionally, ethanol yields from a Simultaneous Saccharification and Fermentation process are improved 5-25% by treatment with a lignin-blocking polypeptide and/or protein.

摘要翻译： 公开了一种在木质纤维素生物质中转化纤维素的方法。 该方法提供高木质素固体的木质素阻断多肽和/或蛋白质处理。 该处理增强纤维素转化中的纤维素酶可用性，并且允许确定优化的预处理条件。 此外，通过用木质素阻断多肽和/或蛋白质处理，来自同时糖化和发酵过程的乙醇产率提高了5-25％。

公开(公告)号：US07604967B2

公开(公告)日：2009-10-20

申请号：US10391740

申请日：2003-03-19

申请人： Bin Yang ,  Charles E. Wyman

发明人： Bin Yang ,  Charles E. Wyman

IPC分类号： C12P7/06

CPC分类号： C12P7/10 ,  C12P7/08 ,  C12P19/02 ,  Y02E50/16 ,  Y02E50/17

摘要： Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion. Cellulase efficiencies are improved by the protein or polypeptide treatment. The treatment may be used in combination with steam explosion and acid prehydrolysis techniques. Hydrolysis yields from lignin containing biomass are enhanced 5-20%, and enzyme utilization is increased from 10% to 50%. Thus, a more efficient and economical method of processing lignin containing biomass materials utilizes a polypeptide/protein treatment step that effectively blocks lignin binding of cellulase.

摘要翻译： 公开了一种在木质纤维素生物质中转化纤维素的方法。 该方法提供高木质素固体的木质素阻断多肽和/或蛋白质处理。 该处理增强了纤维素转化中的纤维素酶可用性。 通过蛋白质或多肽处理改善纤维素酶的效率。 该处理可以与蒸汽爆炸和酸预水解技术结合使用。 含木质素生物质的水解产量提高5-20％，酶利用率从10％提高到50％。 因此，处理含木质素的生物质材料的更有效和经济的方法利用有效阻断木质素结合纤维素酶的多肽/蛋白质处理步骤。

公开(公告)号：US11414817B2

公开(公告)日：2022-08-16

申请号：US17074866

申请日：2020-10-20

申请人： Meiyun Zhang ,  Jiaojun Tan ,  Bin Yang ,  Shunxi Song ,  Jingyi Nie ,  Xue Jiang

发明人： Meiyun Zhang ,  Jiaojun Tan ,  Bin Yang ,  Shunxi Song ,  Jingyi Nie ,  Xue Jiang

IPC分类号： D21H13/26 ,  D21H15/10 ,  D21H17/67 ,  D21H21/08 ,  D06M101/36

摘要： A method of preparing an aramid paper coated with aramid nanofibers includes the following steps: (1) mixing a meta-aramid fibrid slurry and a chopped meta-aramid fiber slurry, filtering, pressing and drying to obtain a meta-aramid paper; (2) mixing potassium hydroxide, deionized water, dimethyl sulfoxide, and para-aramid nanofibers in a container, and stirring to obtain a para-aramid nanofiber coating solution; and (3) applying the para-aramid nanofiber coating solution to a first side of the meta-aramid paper, washing with deionized water, and drying; applying the para-aramid nanofiber coating solution to a second side of the meta-aramid paper, washing with deionized water, and drying; and hot pressing to obtain the aramid paper coated with aramid nanofibers.

公开(公告)号：US09995775B2

公开(公告)日：2018-06-12

申请号：US13877317

申请日：2011-10-13

申请人： Xiuzhen Dong ,  Xuyang Huo ,  Fusheng You ,  Xuetao Shi ,  Feng Fu ,  Ruigang Liu ,  Zhenyu Ji ,  Canhua Xu ,  Bin Yang ,  Min Yang ,  Jiaxue Qi ,  Wen Zhang ,  Nan Wang

发明人： Xiuzhen Dong ,  Xuyang Huo ,  Fusheng You ,  Xuetao Shi ,  Feng Fu ,  Ruigang Liu ,  Zhenyu Ji ,  Canhua Xu ,  Bin Yang ,  Min Yang ,  Jiaxue Qi ,  Wen Zhang ,  Nan Wang

IPC分类号： G01R27/02 ,  A61B5/053 ,  A61B5/00 ,  G01R27/14

CPC分类号： G01R27/02 ,  A61B5/053 ,  A61B5/0536 ,  A61B5/7225 ,  G01R27/14

摘要： A device for detecting electrical impedance by utilizing a theory of excitation and response signals and method thereof, wherein the excitation signal is a square wave excitation current signal (1), the response signal on a target is transformed to a square wave signal with appropriate amplitudes by buffering, amplifying, RC filtering and differential amplifying, then is transformed to a digital signal at a proper time by an analog-to-digital converter. The response signal is sampled once when at high level and once when at low level for every circle by the ADC, and a sample V1 and a sample V2 are obtained respectively, difference of the samples is taken as a detecting result for one circle. An average value of the detecting result from a plurality of circles is taken as a final result. Information of electrical impedance is illustrated by the final result because the excitation current signal is constant.

公开(公告)号：US08981047B2

公开(公告)日：2015-03-17

申请号：US12739342

申请日：2008-10-23

申请人： Richard D. Dimarchi ,  Bin Yang

发明人： Richard D. Dimarchi ,  Bin Yang

IPC分类号： A61K38/26 ,  C07K14/605 ,  C07K14/00 ,  A61K38/00

CPC分类号： C07K14/605 ,  A61K38/00

摘要： Glucagon antagonists are provided which comprise amino acid substitutions and/or chemical modifications to glucagon sequence. In one embodiment, the glucagon antagonists comprise a native glucagon peptide that has been modified by the deletion of the first two to five amino acid residues from the N-terminus and (i) an amino acid substitution at position 9 (according to the numbering of native glucagon) or (ii) substitution of the Phe at position 6 (according to the numbering of native glucagon) with phenyl lactic acid (PLA). In another embodiment, the glucagon antagonists comprise the structure A-B-C as described herein, wherein A is PLA, an oxy derivative thereof, or a peptide of 2-6 amino acids in which two consecutive amino acids of the peptide are linked via an ester or ether bond.

摘要翻译： 提供了包含对胰高血糖素序列的氨基酸取代和/或化学修饰的胰高血糖素拮抗剂。 在一个实施方案中，胰高血糖素拮抗剂包含通过从N-末端缺失前两个至五个氨基酸残基而修饰的天然胰高血糖素肽，以及（i）在第9位的氨基酸取代（根据 天然胰高血糖素）或（ii）用苯基乳酸（PLA）取代第6位的Phe（根据天然胰高血糖素的编号）。 在另一个实施方案中，胰高血糖素拮抗剂包含如本文所述的结构ABC，其中A是PLA，其氧衍生物或2-6个氨基酸的肽，其中肽的两个连续氨基酸经由酯或醚连接 键。

公开(公告)号：US08889087B2

公开(公告)日：2014-11-18

申请号：US13948967

申请日：2013-07-23

申请人： Anna Lee Y. Tonkovich ,  Robert D. Litt ,  Timothy M. Werner ,  Bin Yang

发明人： Anna Lee Y. Tonkovich ,  Robert D. Litt ,  Timothy M. Werner ,  Bin Yang

IPC分类号： B01J8/00 ,  B01J19/18 ,  B01J19/00 ,  C10G2/00 ,  C07C29/152

CPC分类号： B01J19/0093 ,  B01J19/1831 ,  B01J2219/00783 ,  B01J2219/00835 ,  B01J2219/00873 ,  B01J2219/00984 ,  C07C29/152 ,  C10G2/341 ,  C07C31/04

摘要： An integrated microchannel reactor and heat exchanger comprising: (a) a waveform sandwiched between opposing shim sheets and mounted to the shim sheets to form a series of microchannels, where each microchannel includes a pair of substantially straight side walls, and a top wall formed by at least one of the opposing shim sheets, and (b) a first set of microchannels in thermal communication with the waveform, where the waveform has an aspect ratio greater than two.

摘要翻译： 一种集成微通道反应器和热交换器，包括：（a）夹在相对的垫片之间的波形并安装到垫片以形成一系列微通道，其中每个微通道包括一对基本上直的侧壁，以及由 至少一个相对的垫片，和（b）与波形热连通的第一组微通道，其中波形的纵横比大于2。

公开(公告)号：US08741753B2

公开(公告)日：2014-06-03

申请号：US13611736

申请日：2012-09-12

申请人： Kisik Choi ,  Christian Lavoie ,  Paul M. Solomon ,  Bin Yang ,  Zhen Zhang

发明人： Kisik Choi ,  Christian Lavoie ,  Paul M. Solomon ,  Bin Yang ,  Zhen Zhang

IPC分类号： H01L21/20 ,  H01L21/3205 ,  H01L21/00

CPC分类号： H01L29/7833 ,  H01L21/28512 ,  H01L29/4958 ,  H01L29/4966 ,  H01L29/66545

摘要： A device includes a gate stack formed over a channel in a semiconductor substrate. The gate stack includes a layer of gate insulator material, a layer of gate metal overlying the layer of gate insulator material, and a layer of contact metal overlying the layer band edge gate metal. The device further includes source and drain contacts adjacent to the channel. The source and drain contacts each include a layer of the gate metal that overlies and is in direct electrical contact with a doped region of the semiconductor substrate, and a layer of contact metal that overlies the layer of gate metal.

摘要翻译： 一种器件包括形成在半导体衬底中的沟道上方的栅叠层。 栅极堆叠包括栅极绝缘体材料层，覆盖栅极绝缘体材料层的栅极金属层和覆盖层带边缘栅极金属的接触金属层。 该装置还包括邻近通道的源极和漏极接触。 源极和漏极触点各自包括覆盖并与半导体衬底的掺杂区域直接电接触的栅极金属层以及覆盖在栅极金属层上的接触金属层。

公开(公告)号：US08685365B2

公开(公告)日：2014-04-01

申请号：US13747440

申请日：2013-01-22

申请人： James A. Mathias ,  G. Bradley Chadwell ,  Annalee Y. Tonkovich ,  Steven T. Perry ,  Matthew B. Schmidt ,  Sean P. Fitzgerald ,  David J. Hesse ,  Thomas D. Yuschak ,  Bin Yang

发明人： James A. Mathias ,  G. Bradley Chadwell ,  Dongming Qiu ,  Annalee Y. Tonkovich ,  Steven T. Perry ,  Matthew B. Schmidt ,  Sean P. Fitzgerald ,  David J. Hesse ,  Thomas D. Yuschak ,  Bin Yang

IPC分类号： C01B3/24 ,  B01J19/00 ,  B01J8/00

CPC分类号： F16L41/02 ,  B01J19/0093 ,  B01J35/04 ,  B01J2219/00869 ,  B01J2219/00891 ,  C01B3/384 ,  C01B2203/0233 ,  C01B2203/0811 ,  C01B2203/0822 ,  F28D7/0066 ,  F28D9/0093 ,  F28F3/12 ,  F28F7/02 ,  F28F2260/02 ,  Y02P20/128 ,  Y02P20/52 ,  Y10T137/0318 ,  Y10T137/6579 ,  Y10T137/87153 ,  Y10T137/87249

摘要： Provided is a process and device for exchanging heat energy between three or more streams in a microchannel heat exchanger which can be integrated with a microchannel reactor to form an integrated microchannel processing unit. The combining of a plurality of integrated microchannel devices to provide the benefits of large-scale operation is enabled. In particular, the microchannel heat exchanger enables flexible heat transfer between multiple streams and total heat transfer rates of about 1 Watt or more per core unit volume expressed as W/cc.

摘要翻译： 提供了一种用于在微通道热交换器中的三个或更多个流之间交换热能的过程和装置，其可以与微通道反应器集成以形成集成的微通道处理单元。 实现了多个集成微通道装置的组合以提供大规模操作的优点。 特别地，微通道热交换器使得能够在多个流之间实现柔性热传递，并且以W / cc表示的每单位体积的约1瓦或更高的总传热速率。