公开(公告)号：US10012592B2

公开(公告)日：2018-07-03

申请号：US15722486

申请日：2017-10-02

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Adam Abate ,  John Lawrence Emhoff ,  Tony Hung ,  Adnan Moez Esmail ,  Sepehr Kiani ,  Pascaline Mary

IPC: G01J1/10 ,  G01J3/30 ,  G01N21/64 ,  G01N21/76 ,  G01N21/25 ,  C12Q1/6806

CPC classification number: G01N21/6486 ,  C12Q1/6806 ,  G01N21/255 ,  G01N21/76 ,  G01N2201/06113 ,  G01N2201/062 ,  C12Q2545/101 ,  C12Q2563/107 ,  C12Q2563/159 ,  C12Q2563/161 ,  C12Q2565/629

Abstract: The present invention generally pertains to methods and kits for managing the variation in spectroscopic intensity measurements through the use of a reference component. The reference component may comprise a reference spectroscopic substance and may be contained together with a sample of interest in a sample to be tested, wherein the sample of interest may comprise a sample spectroscopic substance. Each sample to be tested may be uniquely identified and, hence, “barcoded” by combinations of different colors and concentrations of spectroscopic substances, contained therein.

公开(公告)号：US10569268B2

公开(公告)日：2020-02-25

申请号：US15822742

申请日：2017-11-27

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Adam Abate ,  Sepehr Kiani ,  Tony Hung ,  Pascaline Mary ,  Adnan Moez Esmail

IPC: B01L3/00 ,  B01F13/00 ,  F04B19/00 ,  F16K99/00

Abstract: The present invention generally pertains to a system for performing injection of multiple substantially controlled volumes into or out of a droplet, and methods and kits comprising the same. The system of the present invention comprises at least one microfluidic channel, one or more injection channels, an injection inlet associated with each of the one or more injection channels, and a mechanism for disrupting an interface between a droplet and a fluid and/or emulsion, wherein the at least one microfluidic channel comprises one or more droplets are flowing therein, and wherein each of the one or more injection channels comprises at least one fluid and/or emulsion therein.