公开(公告)号：US10451535B2

公开(公告)日：2019-10-22

申请号：US15883229

申请日：2018-01-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Edward Marquette

IPC: G01N15/14 ,  G01N15/10 ,  G01R5/28

Abstract: Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.

公开(公告)号：US10126225B2

公开(公告)日：2018-11-13

申请号：US14460580

申请日：2014-08-15

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Edward Marquette

IPC: G01N33/48 ,  G01N15/14 ,  G01N15/10

Abstract: Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.

公开(公告)号：US11237093B2

公开(公告)日：2022-02-01

申请号：US16214674

申请日：2018-12-10

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Fan Xiong ,  Edward Marquette ,  Brian D. Hall ,  Michelle Scott ,  Matthew Alexander

IPC: G01N15/14

Abstract: An external fluidic system and methods of operating the same are provided. The fluidic system can be hot-swap connected to a flow-cytometer-based system at runtime to expand sheath or waste fluid storage capability of the flow-cytometer-based system by making only minimal changes to the flow-cytometer-based system. The external fluidic system can include a pump and a controller configured to operate the external fluidic system such that the sheath fluid is supplied from the external fluidic system to the flow-cytometer-based system or the waste fluid is extracted from the flow-cytometer-teased system and provided to the external fluidic system.

公开(公告)号：US20180156712A1

公开(公告)日：2018-06-07

申请号：US15883229

申请日：2018-01-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Edward Marquette

IPC: G01N15/14 ,  G01N15/10

CPC classification number: G01N15/1404 ,  G01N15/1012 ,  G01N15/1427 ,  G01N2015/1406 ,  G01N2015/149 ,  G01R5/28

Abstract: Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.

公开(公告)号：US20150050638A1

公开(公告)日：2015-02-19

申请号：US14460580

申请日：2014-08-15

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Edward Marquette

IPC: C12Q3/00

CPC classification number: G01N15/1404 ,  G01N15/1012 ,  G01N15/1427 ,  G01N2015/1406 ,  G01N2015/149

Abstract: Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.

Abstract translation: 公开了一种用于根据所收集的带电液滴的电荷来设置流式细胞仪中的流体流或电荷脉冲发生器的定时或相位的液滴分离的时间或相位的系统。 在一个实施例中，可以使用导电网来收集由偏转板偏转或不偏转的带电液滴。 在另一个实施例中，电荷可以从废物收集装置中的金属板收集。 此外，公开了允许充电电池基本上均匀偏转的防止装置。