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公开(公告)号：US20160184813A1
公开(公告)日：2016-06-30
申请号：US15063235
申请日：2016-03-07
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Jiali LIAO , Lee OLECH , Hong CHEN , Xuemei HE , Russell FROST
Abstract: Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix.
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