公开(公告)号：US09663766B2

公开(公告)日：2017-05-30

申请号：US14808699

申请日：2015-07-24

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Mark Irwin Fitchmun

IPC: C12N7/00 ,  B01D15/36

CPC classification number: C12N7/00 ,  B01D15/362 ,  B01D15/363 ,  C12N15/86 ,  C12N2710/10051 ,  C12N2710/10343 ,  C12N2710/10351

Abstract: Methods of purifying an adenovirus from an impure preparation are provided. In some embodiments, a combination of mixed mode chromatography and anion exchange chromatography is used to purify the adenovirus.

公开(公告)号：US20170022479A1

公开(公告)日：2017-01-26

申请号：US14808699

申请日：2015-07-24

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Mark Irwin Fitchmun

IPC: C12N7/00 ,  B01D15/36

CPC classification number: C12N7/00 ,  B01D15/362 ,  B01D15/363 ,  C12N15/86 ,  C12N2710/10051 ,  C12N2710/10343 ,  C12N2710/10351

Abstract: Methods of purifying an adenovirus from an impure preparation are provided. In some embodiments, a combination of mixed mode chromatography and anion exchange chromatography is used to purify the adenovirus.

Abstract translation: 提供从不纯制剂中纯化腺病毒的方法。 在一些实施方案中，使用混合模式层析和阴离子交换层析的组合来纯化腺病毒。