公开(公告)号：US12018971B2

公开(公告)日：2024-06-25

申请号：US17295422

申请日：2019-12-03

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Adam Philip Lins ,  Glenn Leo Price ,  Robert Alan Iovanni

IPC: G01F23/292 ,  G06F16/245 ,  G06T7/62 ,  G06T7/73 ,  G16H10/40 ,  G16H40/40

CPC classification number: G01F23/292 ,  G06F16/245 ,  G06T7/62 ,  G06T7/73 ,  G16H10/40 ,  G16H40/40 ,  G06T2207/10024 ,  G06T2207/30004

Abstract: Disclosed herein are a system and method for determining a liquid level in a container based on data extracted from a digital image of the container. An image capture apparatus captures an image of a container used to store liquid reagents used by analytical instruments to test patient samples. A controller receives the captured image and extracts an analysis region based on a container type and applies a gradient filter to the analysis region. A location of a minimum gradient value (i.e., a row index) is determined based on the air-to-liquid boundary of the liquid in the extracted analysis region. A volume module calculates the liquid level in the analysis region by dividing the row index by a length of a gradient column vector and compares the determined liquid level to a threshold analysis region fraction for the container type to determine whether to output an alert.

公开(公告)号：US20240295426A1

公开(公告)日：2024-09-05

申请号：US18658698

申请日：2024-05-08

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Adam Philip Lins ,  Glenn Leo Price ,  Robert Alan Iovanni

IPC: G01F23/292 ,  G06F16/245 ,  G06T7/62 ,  G06T7/73 ,  G16H10/40 ,  G16H40/40

CPC classification number: G01F23/292 ,  G06F16/245 ,  G06T7/62 ,  G06T7/73 ,  G16H10/40 ,  G16H40/40 ,  G06T2207/10024 ,  G06T2207/30004

Abstract: Disclosed herein are a system and method for determining a liquid level in a container based on data extracted from a digital image of the container. An image capture apparatus captures an image of a container used to store liquid reagents used by analytical instruments to test patient samples. A controller receives the captured image and extracts an analysis region based on a container type and applies a gradient filter to the analysis region. A location of a minimum gradient value (i.e., a row index) is determined based on the air-to-liquid boundary of the liquid in the extracted analysis region. A volume module calculates the liquid level in the analysis region by dividing the row index by a length of a gradient column vector and compares the determined liquid level to a threshold analysis region fraction for the container type to determine whether to output an alert.

公开(公告)号：US20160266099A1

公开(公告)日：2016-09-15

申请号：US15064365

申请日：2016-03-08

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Glenn Price ,  Chris Charlton ,  William Link ,  Robert Alan Iovanni ,  Anthony F. Prestigiacomo

IPC: G01N33/53

CPC classification number: B01L3/5023 ,  B01L3/5025 ,  B01L3/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0621 ,  B01L2200/143 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/069 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2400/0457

Abstract: In one arrangement, a cartridge includes a cartridge body defining a holding compartment, first and second fractioning compartments, and a number of flow channels formed within the cartridge body. A predetermined quantity of fluid can be held in the holding compartment when the cartridge body is held in a first orientation, and can be poured from the holding compartment to the first fractioning compartment by rotating the cartridge body about a predefined rotation axis to a second orientation, spilling the fluid from the holding compartment to the first fractioning compartment through one of the flow channels. The first fractioning compartment is such that when the cartridge body is in the second orientation, not all of the fluid can be contained in the first fractioning compartment, and fluid that overflows the first fractioning compartment flows through a second flow channel to the second fractioning compartment.

Abstract translation: 在一种布置中，盒包括限定保持室，第一和第二分级隔室以及形成在盒体内的多个流动通道的盒体。 当盒体被保持在第一方向时，预定量的流体可以被保持在保持室中，并且可以通过将盒体围绕预定义的旋转轴旋转到第二取向而从保持室倾倒到第一分馏室 通过其中一个流动通道将流体从储藏室溢出到第一分馏室。 第一分馏室使得当盒体处于第二取向时，并非所有流体都可以包含在第一分馏室中，并且溢出第一分馏室的流体流过第二流动通道至第二分馏室 。