PROCESS FOR THE DISTILLATION OF FATTY ACID ESTERS
    2.
    发明申请
    PROCESS FOR THE DISTILLATION OF FATTY ACID ESTERS 有权
    消毒脂肪酸酯的方法

    公开(公告)号:US20130331588A1

    公开(公告)日:2013-12-12

    申请号:US14000443

    申请日:2012-03-03

    IPC分类号: C07C67/54 C07C69/587

    摘要: The present invention relates to a method for working up a mixture which contains esters of EPA and/or DHA with monohydric alcohols having 1 to 6 carbon atoms, esters of other fatty acids with monohydric alcohols having 1 to 6 carbon atoms, and free cholesterol, wherein the method comprises adding a transesterification catalyst to the mixture, converting at least some of the free cholesterol into esterified cholesterol and thereafter distilling the mixture, wherein the distillation is carried out in such a manner that a product is obtained which contains EPA and/or DHA, both in the form of esters thereof with monohydric alcohols having 1 to 6 carbon atoms, in a higher relative amount, based on all fatty acids in free or bound form present in the product, than said mixture. In addition, the present invention relates to a product which is obtainable by the method according to the invention, wherein the product contains 10 to 99.99% by weight of esters of EPA and/or of DHA with monohydric alcohols having 1 to 6 carbon atoms and 0.0001 to a maximum of 0.3% by weight of cholesterol in free or bound form.

    摘要翻译: 本发明涉及一种用于处理含有EPA和/或DHA的酯与具有1至6个碳原子的一元醇的混合物的混合物的方法,其它脂肪酸与具有1至6个碳原子的一元醇的酯和游离胆固醇, 其中所述方法包括向所述混合物中加入酯交换催化剂,将至少一些游离胆固醇转化为酯化胆固醇,然后蒸馏混合物,其中蒸馏是以获得含有EPA和/或 DHA,以其与具有1至6个碳原子的一元醇的酯的形式,以相对于所述混合物中存在的游离或结合形式的所有脂肪酸的相对量较高。 另外本发明涉及通过本发明的方法获得的产品,其中该产品含有10至99.99重量%的EPA和/或DHA的酯与具有1至6个碳原子的一元醇的酯和 0.0001至最大0.3重量%的游离或结合形式的胆固醇。

    Compositions Containing Sterol-derived Esters
    3.
    发明申请
    Compositions Containing Sterol-derived Esters 审中-公开
    含有甾醇衍生酯的组合物

    公开(公告)号:US20090099146A1

    公开(公告)日:2009-04-16

    申请号:US12282172

    申请日:2007-02-27

    IPC分类号: A61K31/56 A61P3/06

    摘要: The invention relates to sterol fatty acid esters of average chained fatty acids, having a chain length of 8 and 10 carbon atoms in a fatty acid distribution C8 to C10 (weight ratio) from 95:5 to 5:95, preferably, fatty acid distributions of C8 to C10 (weight ratio) from 90:10 to 20:80 and in particular, distributions of the fatty acids C8 to C10 (weight ratio) from 64:36 to 50:50 or from 78:22 to 65:35, are used. Preferably, capric and/or caprylic acids are used as fatty acids. Said sterol compounds can be easily incorporated into food, in particular, into drinks and milk products based on their wettability and easy to melt properties at low temperatures without using complex equipment, and have good organolepetic and sensory properties, and improved stability in relation to commercial sterol esters having long-chained and unsaturated fatty acids.

    摘要翻译: 本发明涉及脂肪酸分布C8〜C10(重量比)为95:5〜5:95的链长为8〜10个碳原子的平均链状脂肪酸的甾醇脂肪酸酯,优选为脂肪酸分布 C8〜C10(重量比)为90:10〜20:80,特别是脂肪酸C8〜C10(重量比)为64:36〜50:50或78:22〜65:35的分布, 被使用。 优选地,癸酸和/或辛酸用作脂肪酸。 所述甾醇化合物可以容易地结合到食品中,特别是基于它们的润湿性和在低温下容易熔融的性质而不使用复杂的设备,并且具有良好的有机物和感官特性以及改进的与商业相关的稳定性 具有长链和不饱和脂肪酸的甾醇酯。

    DEVICE AND METHOD FOR DISTILLING TEMPERATURE-SENSITIVE SUBSTANCES
    4.
    发明申请
    DEVICE AND METHOD FOR DISTILLING TEMPERATURE-SENSITIVE SUBSTANCES 审中-公开
    用于蒸馏温度敏感物质的装置和方法

    公开(公告)号:US20130292242A1

    公开(公告)日:2013-11-07

    申请号:US13879040

    申请日:2011-09-23

    IPC分类号: B01D3/14

    CPC分类号: B01D3/148 B01D1/065

    摘要: The present invention relates to an apparatus for the distillation of substance mixtures which comprise temperature-sensitive substances, where the apparatus comprises a thin-film evaporator and a fractionating column, and where the fractionating column is attached to the distillate outlet of the thin-film evaporator, and where the fractionating column has at least 3 theoretical plates, and where the pressure drop of the fractionating column during operation at an F factor of 1 Pa1/2 amounts to a maximum of 3 hPa (3 mbar). Furthermore, the present invention relates to a process for the distillation of substance mixtures which comprise temperature-sensitive substances, which process is carried out in the apparatus according to the invention.

    摘要翻译: 本发明涉及一种用于蒸馏含有温度敏感物质的物质混合物的装置,其中该装置包括薄膜蒸发器和分馏塔,并且其中分馏塔连接到薄膜的馏出物出口 蒸发器,并且分馏塔具有至少3个理论塔板,并且其中在F因子为1Pa 1/2的操作期间分馏塔的压降达到最大3hPa(3mbar)。 此外,本发明涉及蒸馏含有温度敏感物质的物质混合物的方法,该方法在根据本发明的设备中进行。

    Method for producing sterol formulations
    5.
    发明授权
    Method for producing sterol formulations 有权
    甾醇制剂的制备方法

    公开(公告)号:US08414945B2

    公开(公告)日:2013-04-09

    申请号:US12517571

    申请日:2007-11-24

    IPC分类号: A23C21/10

    摘要: The invention relates to a wet grinding method for producing sterol formulations having good wettability. According to said method, a) an additive selected from the group consisting of proteins, proteinaceous adjuvants, carbohydrates, cellulose derivatives, sugar alcohols, fruit concentrates and vegetable concentrates is dissolved or dispersed in water or in an aqueous suspension medium, b) sterol and/or stanol particles having a median particle size of at least 1 mm are added to this solution/dispersion, c) the dispersion thus obtained is homogenized and size-reduced in a mill that works according to the rotor/stator principle, and d) is then optionally dried, with the proviso that the sterol and/or stanol particles are present in the final formulation with a particle size distribution of D90% of not more than 50 μm. Owing to their good wettability, the sterol-containing formulations produced according to this method can be incorporated into food items without complex technology and have good organoleptic and sensory properties especially when used in drinks and dairy products.

    摘要翻译: 本发明涉及一种用于制备具有良好润湿性的甾醇制剂的湿法研磨方法。 根据所述方法,a)将选自蛋白质,蛋白质佐剂,碳水化合物,纤维素衍生物,糖醇,果实浓缩物和植物浓缩物的添加剂溶解或分散在水或水性悬浮介质中,b)固醇和 /或中等粒度为至少1mm的甾烷醇颗粒加入到该溶液/分散体中,c)将所得到的分散体在根据转子/定子原理工作的研磨机中均化并减小,d) 然后任选地干燥,条件是固醇和/或甾烷醇颗粒存在于最终制剂中,其粒度分布为D90%不大于50μm。 由于其良好的润湿性,根据该方法制备的含甾醇的制剂可以并入到没有复杂技术的食品中,并且具有良好的感官和感官特性,特别是当用于饮料和乳制品时。

    Process for the distillation of fatty acid esters
    6.
    发明授权
    Process for the distillation of fatty acid esters 有权
    蒸馏脂肪酸酯的方法

    公开(公告)号:US08889895B2

    公开(公告)日:2014-11-18

    申请号:US14000443

    申请日:2012-03-03

    摘要: The present invention relates to a method for working up a mixture which contains esters of EPA and/or DHA with monohydric alcohols having 1 to 6 carbon atoms, esters of other fatty acids with monohydric alcohols having 1 to 6 carbon atoms, and free cholesterol, wherein the method comprises adding a transesterification catalyst to the mixture, converting at least some of the free cholesterol into esterified cholesterol and thereafter distilling the mixture, wherein the distillation is carried out in such a manner that a product is obtained which contains EPA and/or DHA, both in the form of esters thereof with monohydric alcohols having 1 to 6 carbon atoms, in a higher relative amount, based on all fatty acids in free or bound form present in the product, than said mixture. In addition, the present invention relates to a product which is obtainable by the method according to the invention, wherein the product contains 10 to 99.99% by weight of esters of EPA and/or of DHA with monohydric alcohols having 1 to 6 carbon atoms and 0.0001 to a maximum of 0.3 % by weight of cholesterol in free or bound form.

    摘要翻译: 本发明涉及一种用于处理含有EPA和/或DHA的酯与具有1至6个碳原子的一元醇的混合物的混合物的方法,其它脂肪酸与具有1至6个碳原子的一元醇的酯和游离胆固醇, 其中所述方法包括向所述混合物中加入酯交换催化剂,将至少一些游离胆固醇转化为酯化胆固醇,然后蒸馏混合物,其中蒸馏是以获得含有EPA和/或 DHA,以其与具有1至6个碳原子的一元醇的酯的形式,以相对于所述混合物中存在的游离或结合形式的所有脂肪酸的相对量较高。 另外本发明涉及通过本发明的方法获得的产品,其中该产品含有10至99.99重量%的EPA和/或DHA的酯与具有1至6个碳原子的一元醇的酯和 0.0001至最大0.3重量%的游离或结合形式的胆固醇。

    Method for producing sterol formulations
    7.
    发明申请
    Method for producing sterol formulations 有权
    甾醇制剂的制备方法

    公开(公告)号:US20100068367A1

    公开(公告)日:2010-03-18

    申请号:US12517571

    申请日:2007-11-24

    摘要: The invention relates to a wet grinding method for producing sterol formulations having good wettability. According to said method, a) an additive selected from the group constituted by proteins, proteinaceous adjuvants, carbohydrates, cellulose derivatives, sugar alcohols, fruit concentrates and vegetable concentrates is dissolved or dispersed in water or in an aqueous suspension medium, b) sterol and/or stanol particles having a medium particle size of at least 1 mm are added to this solution/dispersion, c) the dispersion thus obtained is homogenized and size-reduced in a mill that works according to the rotor/stator principle, and d) is then optionally dried, with the proviso that the sterol and/or stanol particles are present in the final formulation with a particle size distribution of D90% of not more than 50 μm. Owing to their good wettability, the sterol-containing formulations produced according to this method can be incorporated into food items without complex technology and have good organoleptic and sensory properties especially when used in drinks and dairy products.

    摘要翻译: 本发明涉及一种用于制备具有良好润湿性的甾醇制剂的湿法研磨方法。 根据所述方法,a)选自蛋白质,蛋白质佐剂,碳水化合物,纤维素衍生物,糖醇,果实浓缩物和植物浓缩物中的添加剂的添加剂溶解或分散在水或水性悬浮介质中,b)固醇和 /或具有至少1mm的中等粒度的甾烷醇颗粒加入到该溶液/分散体中,c)将所得到的分散体在根据转子/定子原理工作的研磨机中均化并减小尺寸,以及d) 然后任选地干燥,条件是固醇和/或甾烷醇颗粒存在于最终制剂中,其粒度分布为D90%不大于50μm。 由于其良好的润湿性,根据该方法制备的含甾醇的制剂可以并入到没有复杂技术的食品中,并且具有良好的感官和感官特性,特别是当用于饮料和乳制品时。

    Sterol-Containing Compositions
    8.
    发明申请
    Sterol-Containing Compositions 审中-公开
    含甾醇的成分

    公开(公告)号:US20100055190A1

    公开(公告)日:2010-03-04

    申请号:US12282171

    申请日:2007-02-27

    IPC分类号: A61K9/14 A61K31/56 A61P9/10

    摘要: The invention relates to a powder formulation containing sterol in the form of a super-cooled melt from sterols and sterol esters, provided that the sterol ester content is at least 30 wt % in relation to the content of the powder. The introduced sterol ester is a fatty acid ester having a chain length of 2 to 24, preferably 8 to 12 carbon atoms. As the sterol preparations are wettable and melt easily without the use of complex equipment, they can easily be incorporated into food, and produce, in particular, good organoleptic and sensory properties, in particular, in drinks.

    摘要翻译: 本发明涉及一种粉末制剂,其含有来自甾醇和甾醇酯的过冷却熔体形式的固醇,条件是相对于粉末含量,甾醇酯含量至少为30重量%。 引入的甾醇酯是链长为2至24,优选8至12个碳原子的脂肪酸酯。 由于甾醇制剂在不使用复杂设备的情况下易于润湿和熔化,因此它们可以容易地并入食物中,特别是特别是在饮料中产生良好的感官和感官特性。

    Method for Producing Sterol Formulations
    9.
    发明申请
    Method for Producing Sterol Formulations 审中-公开
    生产甾醇制剂的方法

    公开(公告)号:US20100021525A1

    公开(公告)日:2010-01-28

    申请号:US12517599

    申请日:2007-11-24

    IPC分类号: A61K9/14 A23L1/30

    摘要: The invention relates to a method for producing coated sterol powders. According to said method, a) micronized sterol and/or stanol particles are provided in a mixer, b) the micronized sterol and/or stanol particles are wetted with a proteinaceous aqueous solution/dispersion, c) the wetted particles are mixed well and then dried, and d) the dried mixture is optionally size-reduced in a mill. Owing to their good wettability, the sterol-containing formulations produced according to this method can be incorporated into food items without technical complications and have good organoleptic and sensory properties especially when used in drinks and dairy products.

    摘要翻译: 本发明涉及一种生产涂层甾醇粉末的方法。 根据所述方法,a)在混合器中提供微粉化的甾醇和/或甾烷醇颗粒,b)微粉化的甾醇和/或甾烷醇颗粒用蛋白质水溶液/分散体润湿,c)将润湿的颗粒充分混合,然后 干燥,和d)干燥的混合物任选在研磨机中大小减小。 由于其良好的润湿性,根据该方法制备的含甾醇的制剂可以并入食品中而没有技术并发症,并且具有良好的感官和感官特性,特别是当用于饮料和乳制品时。