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1.
公开(公告)号:US09103819B2
公开(公告)日:2015-08-11
申请号:US12867442
申请日:2009-09-09
IPC分类号: G01N33/574 , C12N5/09 , G01N33/50 , C12N5/079 , A61P35/00
CPC分类号: G01N33/5011 , C12N5/0618 , C12N5/0622 , C12N5/0693 , G01N33/5017 , G01N33/502 , G01N33/5058 , G01N33/574 , G01N2333/705 , G01N2333/70596 , G01N2500/10
摘要: The present invention relates to a tumor cell of the peripheral zone of a tumor and methods of providing such a tumor cell. Further provided is a method for identifying a molecular marker diagnostic for an infiltrative cancer, an antibody, which specifically binds to such molecular marker, a method for identifying a therapeutic compound effective against a metastatic/infiltrative cancer disease and the use of a tumor cell according to the invention.
摘要翻译: 本发明涉及肿瘤周边区域的肿瘤细胞和提供这种肿瘤细胞的方法。 进一步提供一种用于鉴定渗透性癌症的分子标记物的诊断方法,特异性结合该分子标记物的抗体,鉴定对转移性/浸润性癌症有效的治疗化合物的方法以及肿瘤细胞的用途 涉及本发明。
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2.
公开(公告)号:US20110052642A1
公开(公告)日:2011-03-03
申请号:US12867442
申请日:2009-09-09
CPC分类号: G01N33/5011 , C12N5/0618 , C12N5/0622 , C12N5/0693 , G01N33/5017 , G01N33/502 , G01N33/5058 , G01N33/574 , G01N2333/705 , G01N2333/70596 , G01N2500/10
摘要: The present invention relates to a tumor cell of the peripheral zone of a tumor and methods of providing such a tumor cell. Further provided is a method for identifying a molecular marker diagnostic for an infiltrative cancer, an antibody, which specifically binds to such molecular marker, a method for identifying a therapeutic compound effective against a metastatic/infiltrative cancer disease and the use of a tumor cell according to the invention.
摘要翻译: 本发明涉及肿瘤周边区域的肿瘤细胞和提供这种肿瘤细胞的方法。 进一步提供一种用于鉴定渗透性癌症的分子标记物的诊断方法,特异性结合该分子标记物的抗体,鉴定对转移性/浸润性癌症有效的治疗化合物的方法以及肿瘤细胞的用途 涉及本发明。
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