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公开(公告)号：US10272184B2
公开(公告)日：2019-04-30
申请号：US15597541
申请日：2017-05-17
IPC分类号： A61F2/00 , C08J5/18 , C08L5/04 , C08L5/08 , A61L31/04 , A61L31/14 , A61L31/16 , C08J3/075 , C08L89/06
摘要： A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
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2.发明申请公开(公告)号：US20170312397A1
公开(公告)日：2017-11-02
申请号：US15596685
申请日：2017-05-16
发明人： Sarah Mayes , Christine E. Schmidt
IPC分类号： A61L31/04 , A61L31/14 , A61K31/192 , A61L31/16 , A61K31/195
CPC分类号： A61L31/041 , A61K31/192 , A61K31/195 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/43 , A61L2300/62 , C08L5/08 , C08L5/04
摘要： A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
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3.发明授权公开(公告)号：US09656001B2
公开(公告)日：2017-05-23
申请号：US14803258
申请日：2015-07-20
发明人： Sarah Mayes , Christine E. Schmidt
IPC分类号： A61L31/04 , A61K31/192 , A61K31/195 , A61L31/14 , A61L31/16
CPC分类号： A61L31/041 , A61K31/192 , A61K31/195 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/43 , A61L2300/62 , C08L5/08 , C08L5/04
摘要： A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
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公开(公告)号：US20190216987A1
公开(公告)日：2019-07-18
申请号：US16359102
申请日：2019-03-20
CPC分类号： A61L31/145 , A61F2/0077 , A61F2002/009 , A61L31/041 , A61L31/148 , A61L31/16 , C08J3/075 , C08J5/18 , C08J2305/04 , C08J2405/08 , C08L5/04 , C08L5/08 , C08L89/06
摘要： A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
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5.发明授权公开(公告)号：US10314950B2
公开(公告)日：2019-06-11
申请号：US15596685
申请日：2017-05-16
发明人： Sarah Mayes , Christine E. Schmidt
IPC分类号： A61L31/04 , A61K31/192 , A61K31/195 , A61L31/14 , A61L31/16
摘要： A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
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公开(公告)号：US20170252491A1
公开(公告)日：2017-09-07
申请号：US15597541
申请日：2017-05-17
IPC分类号： A61L31/14 , C08J5/18 , A61L31/04 , C08L89/06 , C08J3/075 , C08L5/04 , C08L5/08 , A61F2/00 , A61L31/16
CPC分类号： A61L31/145 , A61F2/0077 , A61F2002/009 , A61L31/041 , A61L31/148 , A61L31/16 , C08J3/075 , C08J5/18 , C08J2305/04 , C08J2405/08 , C08L5/04 , C08L5/08 , C08L89/06
摘要： A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
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公开(公告)号：US20230173144A1
公开(公告)日：2023-06-08
申请号：US18159756
申请日：2023-01-26
CPC分类号： A61L31/145 , A61F2/0077 , C08J5/18 , C08J3/075 , A61L31/041 , A61L31/148 , A61L31/16 , C08J2405/08 , C08J2305/04 , A61F2002/009
摘要： A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
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8.发明授权公开(公告)号：US11058802B2
公开(公告)日：2021-07-13
申请号：US16400259
申请日：2019-05-01
发明人： Sarah Mayes , Christine E. Schmidt
IPC分类号： A61L31/04 , A61K31/195 , A61L31/14 , A61K31/192 , A61L31/16
摘要： A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
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公开(公告)号：US20210069388A1
公开(公告)日：2021-03-11
申请号：US16952155
申请日：2020-11-19
摘要： A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.
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10.发明申请Anti-Adhesive Barrier Membrane Using Alginate and Hyaluronic Acid for Biomedical Applications 有权使用藻酸盐和透明质酸的抗粘膜屏障膜用于生物医学应用公开(公告)号：US20160015866A1
公开(公告)日：2016-01-21
申请号：US14803258
申请日：2015-07-20
发明人： Sarah Mayes , Christine E. Schmidt
CPC分类号： A61L31/041 , A61K31/192 , A61K31/195 , A61L31/145 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/43 , A61L2300/62 , C08L5/08 , C08L5/04
摘要： A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
摘要翻译： 本文公开了非合成的，亲水的，可生物降解的，生物相容性多糖类的无毒抗粘附水凝胶屏障。 本发明的屏障通过构造具有独特孔隙度的独特的互穿交联网络形成。 此外，本发明的屏障由可调节的生物聚合物组成，用于可控的机械稳健性和降解性。 本发明的屏障有效地减少了使用非合成组分的有害粘连。
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