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公开(公告)号：US20210095020A1
公开(公告)日：2021-04-01
申请号：US16871382
申请日：2020-05-11
发明人： Markus ZETTL , Ivo LORENZ , Otmar SCHAFF , Melanie WURM , Jean-Francois FORTIN , Scott Ronald BRODEUR , Keith A. CANADA , Lukasz CHLEWICKI , Walter Carroll DAVIDSON , Pankaj GUPTA , Priyanka GUPTA , Rocío K. PÉREZ , Joseph Robert WOSKA, JR. , Haiguang XIAO , Danlin YANG
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06
摘要： The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
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公开(公告)号：US20170058038A1
公开(公告)日：2017-03-02
申请号：US15252308
申请日：2016-08-31
发明人： Scott Ronald BRODEUR , Thomas B. FREEMAN , Gerald Henry NABOZNY , Meera RAMANUJAM , Paul SCHOLL , Juergen STEFFGEN
IPC分类号： C07K16/28
CPC分类号： C07K16/2878 , C07K2317/24 , C07K2317/71 , C07K2317/76
摘要： The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same for treating and/or preventing lupus nephritis.
摘要翻译： 本发明涉及新的人源化拮抗性抗CD40抗体及其用于治疗和/或预防狼疮性肾炎的治疗和诊断方法和组合物。
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公开(公告)号：US20220153857A1
公开(公告)日：2022-05-19
申请号：US17665909
申请日：2022-02-07
发明人： Rachel Rebecca BARRETT , Scott Ronald BRODEUR , Keith CANADA , Tobias Litzenburger , Sanjaya Singh
摘要： The present invention related to new humanized antanogistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20190309034A1
公开(公告)日：2019-10-10
申请号：US16451333
申请日：2019-06-25
发明人： Scott Ronald BRODEUR , Keith A. CANADA , Michael DZIEGELEWSKI , Philip Nicholas GORMAN , Pankaj GUPTA , Ashraf KHALIL , John J. MIGLIETTA , Amy Marie NICOLETTI , Qi PAN , David PRESKY , Sanjaya SINGH , Tao WU , Haiguang XIAO
IPC分类号： C07K14/475 , A61K39/395 , C07K16/28 , C07K16/24
摘要： The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20180127474A1
公开(公告)日：2018-05-10
申请号：US15803993
申请日：2017-11-06
发明人： Scott Ronald BRODEUR , Keith A. CANADA , Michael DZIEGELEWSKI , Philip Nicholas GORMAN , Pankaj GUPTA , Ashraf KHALIL , John J. MIGLIETTA , Amy Marie NICOLETTI , Qi PAN , David PRESKY , Sanjaya SINGH , Tao WU , Haiguang XIAO
IPC分类号： C07K14/475 , C07K16/28
CPC分类号： C07K14/475 , A61K39/3955 , A61K2039/505 , C07K16/18 , C07K16/241 , C07K16/2875 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20150218267A1
公开(公告)日：2015-08-06
申请号：US14609756
申请日：2015-01-30
发明人： Scott Ronald BRODEUR , Keith CANADA , MIchael DZIEGELEWSKI , Philip Nicholas GORMAN , Pankaj GUPTA , Ashraf KHALIL , John James MIGLIETTA , Amy Marie NICOLETTI , Qi PAN , David PRESKY , Sanjaya SINGH , Tao WU , Haiguang Xiao
IPC分类号： C07K16/24
CPC分类号： C07K14/475 , A61K39/3955 , A61K2039/505 , C07K16/18 , C07K16/241 , C07K16/2875 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
摘要翻译： 本发明涉及抗BAFF抗体分子，包括新型人源化抗BAFF抗体，其用途及其用途的治疗和诊断方法及组合物。
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公开(公告)号：US20230265203A1
公开(公告)日：2023-08-24
申请号：US17962099
申请日：2022-10-07
发明人： Scott Ronald BRODEUR , Thomas B. FREEMAN , Gerald Henry Nabozny , Meera RAMANUJAM , Paul SCHOLL , Juergen STEFFGEN
IPC分类号： C07K16/28
CPC分类号： C07K16/2878 , C07K2317/24 , C07K2317/71 , C07K2317/76
摘要： The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same for treating and/or preventing lupus nephritis.
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公开(公告)号：US20170058039A1
公开(公告)日：2017-03-02
申请号：US15341085
申请日：2016-11-02
发明人： Rachel Rebecca BARRETT , Scott Ronald BRODEUR , Keith CANADA , Tobias LITZENBURGER , Sanjaya SINGH
CPC分类号： C07K16/2878 , A61K9/0019 , A61K2039/505 , C07K1/22 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/53 , C07K2317/565 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same.
摘要翻译： 本发明涉及新的人源化拮抗性抗CD40抗体及其使用的治疗和诊断方法及组合物。
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公开(公告)号：US20160222124A1
公开(公告)日：2016-08-04
申请号：US15098388
申请日：2016-04-14
发明人： Rachel Rebecca BARRETT , Scott Ronald BRODEUR , Keith CANADA , Tobias LITZENBURGER , Sanjaya SINGH
CPC分类号： C07K16/2878 , A61K9/0019 , A61K2039/505 , C07K1/22 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/53 , C07K2317/565 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to new humanized antagonistic anti-CD40 antibodies and therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20240124581A1
公开(公告)日：2024-04-18
申请号：US18459590
申请日：2023-09-01
发明人： Markus ZETTL , Ivo LORENZ , Otmar SCHAAF , Melanie WURM , Jean-Francois FORTIN , Scott Ronald BRODEUR , Keith A. CANADA , Lukasz CHLEWICKI , Walter Carroll DAVIDSON , Pankaj GUPTA , Priyanka GUPTA , Rocío K. PÉREZ , Joseph Robert WOSKA, Jr. , Haiguang XIAO , Danlin YANG
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , C07K16/2818 , C07K16/2827 , A61K2039/505
摘要： The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
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