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公开(公告)号：US20210107983A1
公开(公告)日：2021-04-15
申请号：US17060111
申请日：2020-10-01
发明人： Susanne HIPP , Paul ADAM , Michael DZIEGELEWSKI , Rajkumar GANESAN , Philip Nicholas GORMAN , Pankaj GUPTA , Priyanka GUPTA , Marcio LASARO , Justin M. SCHEER , Vladimir M. VOYNOV
摘要： The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
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公开(公告)号：US20220363743A1
公开(公告)日：2022-11-17
申请号：US17842904
申请日：2022-06-17
IPC分类号： C07K16/22
摘要： The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.
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公开(公告)号：US20230340130A1
公开(公告)日：2023-10-26
申请号：US18337693
申请日：2023-06-20
发明人： Susanne HIPP , Paul ADAM , Michael DZIEGELEWSKI , Rajukumar GANESAN , Phillip Nicholas GORMAN , Pankaj GUPTA , Priyanka GUPTA , Marcio LASARO , Justin M. SCHEER , Vladimir H. VOYNOV
CPC分类号： C07K16/2827 , A61P35/00 , C07K16/2809 , C07K2317/31 , C07K2317/565
摘要： The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
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公开(公告)号：US20230295337A1
公开(公告)日：2023-09-21
申请号：US18327456
申请日：2023-06-01
发明人： Susanne HIPP , Paul ADAM , Michael DZIEGELEWSKI , Rajkumar GANESAN , Philip Nicholas GORMAN , Pankaj GUPTA , Priyanka GUPTA , Justin SCHEER , Vladimir H. VOYNOV
IPC分类号： C07K16/30 , A61P35/00 , C07K1/14 , C07K16/28 , G01N33/577 , C07K16/22 , A61K39/395 , C12N5/10 , C12N15/63
CPC分类号： C07K16/30 , A61P35/00 , C07K1/14 , C07K16/2809 , G01N33/577 , C07K16/22 , A61K39/3955 , C12N5/10 , C12N15/63 , A61K45/06
摘要： The present invention relates to novel DLL3/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
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公开(公告)号：US20240101689A1
公开(公告)日：2024-03-28
申请号：US18520650
申请日：2023-11-28
发明人： Rolf HERRMANN , Remko Alexander BAKKER , Sebastian BANDHOLTZ , Peter Michael BENZ , Michael DZIEGELEWSKI , Lore Katharina FLORIN , Cynthia Hess KENNY , Sarah Kathleen LOW , Holger ROSENBROCK , Sanjaya SINGH , Heiko Friedrich STAHL , Sathyadevi VENKATARAMANI , Vladimir H. VOYNOV , Haiguang XIAO
CPC分类号： C07K16/2863 , A61P25/28 , A61K2039/505 , C07K2317/56 , C07K2317/565
摘要： The present invention relates to novel agonistic anti-TrkB antibodies and therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20190309034A1
公开(公告)日：2019-10-10
申请号：US16451333
申请日：2019-06-25
发明人： Scott Ronald BRODEUR , Keith A. CANADA , Michael DZIEGELEWSKI , Philip Nicholas GORMAN , Pankaj GUPTA , Ashraf KHALIL , John J. MIGLIETTA , Amy Marie NICOLETTI , Qi PAN , David PRESKY , Sanjaya SINGH , Tao WU , Haiguang XIAO
IPC分类号： C07K14/475 , A61K39/395 , C07K16/28 , C07K16/24
摘要： The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
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公开(公告)号：US20180127474A1
公开(公告)日：2018-05-10
申请号：US15803993
申请日：2017-11-06
发明人： Scott Ronald BRODEUR , Keith A. CANADA , Michael DZIEGELEWSKI , Philip Nicholas GORMAN , Pankaj GUPTA , Ashraf KHALIL , John J. MIGLIETTA , Amy Marie NICOLETTI , Qi PAN , David PRESKY , Sanjaya SINGH , Tao WU , Haiguang XIAO
IPC分类号： C07K14/475 , C07K16/28
CPC分类号： C07K14/475 , A61K39/3955 , A61K2039/505 , C07K16/18 , C07K16/241 , C07K16/2875 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
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