公开(公告)号：US09694170B2

公开(公告)日：2017-07-04

申请号：US13709429

申请日：2012-12-10

Applicant: Brainlab AG

Inventor： Christoph Pedain ,  Andreas Hartlep

IPC: A61M5/14 ,  A61M37/00 ,  A61M5/142 ,  A61B34/20

CPC classification number: A61M37/00 ,  A61B2034/2055 ,  A61M5/142 ,  A61M2005/14292 ,  A61M2210/1071

Abstract: A method for planning an infusion into hepatic tissue into a patient includes: obtaining anatomical and/or physiological patient data of the patient's liver or a region of the liver; determining at least one patient parameter from the patient data; planning the infusion using the anatomical patient data, physiological patient data, and/or at least one patient parameter, wherein planning includes determining how an administered substance is distributed in the tissue and/or how the administered substance influences physiological properties of the tissue; and determining a distribution and/or effectiveness of a therapeutic agent administered with the substance or after the substance.

公开(公告)号：US20160015951A9

公开(公告)日：2016-01-21

申请号：US13709429

申请日：2012-12-10

Applicant: Brainlab AG

Inventor： Christoph Pedain ,  Andreas Hartlep

IPC: A61M37/00

CPC classification number: A61M37/00 ,  A61B2034/2055 ,  A61M5/142 ,  A61M2005/14292 ,  A61M2210/1071

Abstract: A method for planning an infusion into hepatic tissue into a patient includes: obtaining anatomical and/or physiological patient data of the patient's liver or a region of the liver; determining at least one patient parameter from the patient data; planning the infusion using the anatomical patient data, physiological patient data, and/or at least one patient parameter, wherein planning includes determining how an administered substance is distributed in the tissue and/or how the administered substance influences physiological properties of the tissue; and determining a distribution and/or effectiveness of a therapeutic agent administered with the substance or after the substance.

Abstract translation: 一种用于规划将肝组织输注入患者的方法包括：获得患者肝脏或肝脏区域的解剖学和/或生理学患者数据; 从所述患者数据确定至少一个患者参数; 使用解剖患者数据，生理学患者数据和/或至少一个患者参数来计划输注，其中规划包括确定给药物质如何分布在组织中和/或所施用的物质如何影响组织的生理特性; 以及确定施用该物质或物质后的治疗剂的分布和/或有效性。

公开(公告)号：US20140180239A1

公开(公告)日：2014-06-26

申请号：US14164667

申请日：2014-01-27

Applicant: Brainlab AG

Inventor： Stephan Mittermeyer ,  Andreas Hartlep

IPC: A61M25/00 ,  A61M5/168

CPC classification number: A61M25/0043 ,  A61B5/02158 ,  A61B5/031 ,  A61B5/036 ,  A61B5/6852 ,  A61B2562/0247 ,  A61M5/16854 ,  A61M5/1723 ,  A61M25/00 ,  A61M2005/14292 ,  A61M2025/0002

Abstract: A catheter for administering a substance into a patient's tissue including a number of pressure sensors for detecting changes in the shape of the catheter or s a backflow along the surface of the catheter. In response to the pressure distribution profile collected along the surface or length of the catheter, the physician may simulate or adapt the substance administration plan to accommodate the actual position of the catheter or the backflow along the surface of the catheter.

Abstract translation: 一种用于将物质施用到患者组织中的导管，包括用于检测导管形状的变化的多个压力传感器或沿着导管表面的回流。 响应于沿着导管的表面或长度收集的压力分布曲线，医师可以模拟或调整物质管理计划以适应导管的实际位置或沿导管表面的回流。