公开(公告)号：US09623969B2

公开(公告)日：2017-04-18

申请号：US14599464

申请日：2015-01-17

Applicant: Brian Dale Nelson

Inventor： Brian Dale Nelson

IPC: B64C27/22 ,  B64C39/02

CPC classification number: B64C39/024 ,  B64C2201/027 ,  B64C2201/042 ,  B64C2201/104 ,  Y02T50/62

Abstract: An unmanned aerial vehicle (UAV) that can operate both as a conventional multicopter with no wing attached, or, it can operate as a winged multicopter. The detachable wing design used in the invention provides versatility without compromising performance; the wing attachment receptacles add no weight to the wingless multicopter configuration because they also function as the leg receptacles. In one embodiment, the base multicopter configuration is a quad-copter with four propeller drives. Four tubular receptacles, two forward and two aft, provide attachment points for the vertical struts of a detachable rectangular shaped wing, these vertical struts also function as the legs of the multicopter. The wing is fabricated using lightweight struts and rip stop nylon fabric which can be easily folded into a compact shape using quick release pins. In another embodiment, the wing is fabricated using a foam core. In both embodiments, the angle of the detachable wing can be adjusted to optimize lift and drag in the forward thrust, tilted position of the multicopter.

公开(公告)号：US20150329204A1

公开(公告)日：2015-11-19

申请号：US14281862

申请日：2014-05-19

Applicant: Brian Dale Nelson

Inventor： Brian Dale Nelson

IPC: B64C39/02

CPC classification number: B64C39/024 ,  B64C27/26 ,  B64C2201/021 ,  B64C2201/024 ,  B64C2201/107 ,  B64C2201/108

Abstract: An unmanned aerial vehicle (UAV) comprising a plurality of propeller drives rigidly mounted to a foldable frame with the motor rotors aligned in a vertical direction to provide a means of vertical takeoffs and landings. The foldable frame mounts a sheet sail at an angle with the horizontal that provides lift during the forward motion and tilt of the UAV. In one embodiment the shape of the sheet sail and frame are triangular with one or two propeller drives being mounted in close proximity to each of the three vertices. In another embodiment, the shape of the sheet sail and frame are triangular with one or two propeller drives being mounted in close proximity to each of the three vertices, and one or two propeller drives being mount in close proximity to the trailing edge of the spine, in between the trailing edge propeller drives. In some embodiments, the frame spars may be comprised of carbon fiber rods and the sheet sail may be comprised of ripstop nylon fabric.

Abstract translation: 一种无人驾驶飞行器（UAV），其包括刚性地安装到可折叠框架的多个螺旋桨驱动器，其中马达转子在垂直方向上对准以提供垂直起飞和降落的装置。 可折叠框架以与水平方向成一定角度安装片材帆，在无人机的向前运动和倾斜期间提供升力。 在一个实施例中，片材帆和框架的形状是三角形的，其中一个或两个螺旋桨驱动器安装在三个顶点中的每一个附近。 在另一个实施例中，片材帆和框架的形状是三角形的，其中一个或两个螺旋桨驱动器安装在三个顶点中的每一个附近，并且一个或两个螺旋桨驱动器安装在脊柱的后缘附近 在后缘螺旋桨驱动器之间。 在一些实施例中，框架翼梁可以​​由碳纤维杆组成，片材帆可以由防撕裂尼龙织物组成。

公开(公告)号：US20160272316A1

公开(公告)日：2016-09-22

申请号：US14599464

申请日：2015-01-17

Applicant: Brian Dale Nelson

Inventor： Brian Dale Nelson

IPC: B64C39/02 ,  B64D27/24 ,  B64C3/00 ,  B64C27/08 ,  B64C3/18

CPC classification number: B64C39/024 ,  B64C2201/027 ,  B64C2201/042 ,  B64C2201/104 ,  Y02T50/62

Abstract: An unmanned aerial vehicle (UAV) that can operate both as a conventional multicopter with no wing attached, or, it can operate as a winged multicopter. The detachable wing design used in the invention provides versatility without compromising performance; the wing attachment receptacles add no weight to the wingless multicopter configuration because they also function as the leg receptacles. In one embodiment, the base multicopter configuration is a quad-copter with four propeller drives. Four tubular receptacles, two forward and two aft, provide attachment points for the vertical struts of a detachable rectangular shaped wing, these vertical struts also function as the legs of the multicopter. The wing is fabricated using lightweight struts and rip stop nylon fabric which can be easily folded into a compact shape using quick release pins. In another embodiment, the wing is fabricated using a foam core. In both embodiments, the angle of the detachable wing can be adjusted to optimize lift and drag in the forward thrust, tilted position of the multicopter.

Abstract translation: 无人驾驶飞行器（UAV）既可以作为常规的多机器人操作，也可以不用机翼连接，也可以作为多翼飞机操作。 本发明中使用的可拆卸机翼设计提供多功能性而不损害性能; 机翼附件插座不会对无翼多机配置增加重量，因为它们也起到腿部插座的作用。 在一个实施例中，基本多机配置是具有四个螺旋桨驱动器的四方交换机。 四个管状容器，两个前部和两个后部，为可拆卸的矩形翼的垂直支柱提供连接点，这些垂直支柱也用作多机器的腿部。 机翼采用轻质支撑和撕裂止挡尼龙织物制成，可以使用快速释放销将其轻松折叠成紧凑形状。 在另一个实施例中，翼使用泡沫芯制造。 在两个实施例中，可拆卸翼的角度可以被调节以优化多机器的向前推力，倾斜位置的升力和阻力。

公开(公告)号：US20170368433A1

公开(公告)日：2017-12-28

申请号：US15194268

申请日：2016-06-27

Applicant: Brian Dale Nelson

Inventor： Brian Dale Nelson

IPC: A63B65/12 ,  A63B67/00

CPC classification number: A63B65/12 ,  A63B67/002 ,  A63B69/40 ,  A63B69/407

Abstract: A one or two player ball game assembly comprising a motorized ball launcher that shoots balls upwards into the air in a random fountain like pattern. Each player catches or retrieves the launched balls and places them back into their designated reservoir. The reservoir gravity feeds the balls back into a striker mechanism. In one embodiment, the reservoirs are clear tubes so that each player may monitor the number of balls in each player's reservoir during play. The clear tubes also act as a fence, keeping each player on their respective sides thus minimizing possible collisions during play. In one embodiment, the game operates on an adjustable timer (e.g. 1-15 minutes) which automatically terminates powered to the motorized striker. The timer may also trigger an audible signal (e.g. bell) when the game is over. The winner is the player with the most balls in their reservoir at the end of play. In the single player game, a single reservoir is used and the player's score is the number of balls in the reservoir when the game ends.

公开(公告)号：US09272784B2

公开(公告)日：2016-03-01

申请号：US14281862

申请日：2014-05-19

Applicant: Brian Dale Nelson

Inventor： Brian Dale Nelson

IPC: B64C27/08 ,  B64C39/02

CPC classification number: B64C39/024 ,  B64C27/26 ,  B64C2201/021 ,  B64C2201/024 ,  B64C2201/107 ,  B64C2201/108

Abstract: An unmanned aerial vehicle (UAV) comprising a plurality of propeller drives rigidly mounted to a foldable frame with the motor rotors aligned in a vertical direction to provide a means of vertical takeoffs and landings. The foldable frame mounts a sheet sail at an angle with the horizontal that provides lift during the forward motion and tilt of the UAV. In one embodiment the shape of the sheet sail and frame are triangular with one or two propeller drives being mounted in close proximity to each of the three vertices. In another embodiment, the shape of the sheet sail and frame are triangular with one or two propeller drives being mounted in close proximity to each of the three vertices, and one or two propeller drives being mount in close proximity to the trailing edge of the spine, in between the trailing edge propeller drives. In some embodiments, the frame spars may be comprised of carbon fiber rods and the sheet sail may be comprised of ripstop nylon fabric.

Abstract translation: 一种无人驾驶飞行器（UAV），其包括刚性地安装到可折叠框架的多个螺旋桨驱动器，其中马达转子在垂直方向上对准以提供垂直起飞和降落的装置。 可折叠框架以与水平方向成一定角度安装片材帆，在无人机的向前运动和倾斜期间提供升力。 在一个实施例中，片材帆和框架的形状是三角形的，其中一个或两个螺旋桨驱动器安装在三个顶点中的每一个附近。 在另一个实施例中，片材帆和框架的形状是三角形的，其中一个或两个螺旋桨驱动器安装在三个顶点中的每一个附近，并且一个或两个螺旋桨驱动器安装在脊柱的后缘附近 在后缘螺旋桨驱动器之间。 在一些实施例中，框架翼梁可以​​由碳纤维杆组成，片材帆可以由防撕裂尼龙织物组成。

公开(公告)号：US08957038B2

公开(公告)日：2015-02-17

申请号：US13383560

申请日：2010-07-15

Applicant: Dinah W. Y. Sah ,  Andrei P. Guzaev ,  Matthew H. Adams ,  Pei Ge ,  Muthiah Manoharan ,  Douglas Ulen Gwost ,  Gregory Robert Stewart ,  David Kent Stiles ,  Brian Dale Nelson ,  William Frederick Kaemmerer ,  Don Marshall Gash

Inventor： Dinah W. Y. Sah ,  Andrei P. Guzaev ,  Matthew H. Adams ,  Pei Ge ,  Muthiah Manoharan ,  Douglas Ulen Gwost ,  Gregory Robert Stewart ,  David Kent Stiles ,  Brian Dale Nelson ,  William Frederick Kaemmerer ,  Don Marshall Gash

IPC: A61K31/70 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  C12Q1/68

CPC classification number: A61K51/0491 ,  A61K49/04 ,  A61K49/06 ,  A61M5/007 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/321 ,  C12N2310/346 ,  C12N2310/3517 ,  C12N2320/10 ,  C12N2320/35 ,  C12N2310/3521

Abstract: This invention provides treatment compositions as well as systems and methods of determining and administering an effective amount of treatment for a neurological disorder. The treatment composition can contain a labeled interfering RNA (iRNA) agent capable of decreasing expression of a target RNA associated with the neurological disorder. The methods of the invention include determining an effective amount of a therapeutic composition by introducing a solution containing a tracer into the brain of a mammal. The tracing solution is monitored until a target volume of distribution at steady state distribution is substantially achieved, and the rate of delivery of the therapeutic composition is determined. The therapeutic composition can then be administered at the rate determined by use of the tracing solution.

Abstract translation: 本发明提供治疗组合物以及确定和施用有效量的神经障碍治疗的系统和方法。 治疗组合物可以含有能够降低与神经障碍相关的靶RNA表达的标记的干扰RNA（iRNA）试剂。 本发明的方法包括通过将含有示踪剂的溶液引入哺乳动物的脑中来确定治疗组合物的有效量。 监测追踪溶液，直到基本上达到稳定状态分布的目标体积分布，并确定治疗组合物的递送速率。 然后可以以通过使用追踪溶液确定的速率施用治疗组合物。

公开(公告)号：US20120116360A1

公开(公告)日：2012-05-10

申请号：US13383560

申请日：2010-07-15

Applicant: Dinah W. Y. Sah ,  Andrei P. Guzaev ,  Matthew H. Adams ,  Pei Ge ,  Muthiah Manoharan ,  Douglas Ulen Gwost ,  Gregory Robert Stewart ,  David Kent Stiles ,  Brian Dale Nelson ,  William Frederick Kaemmerer ,  Don Marshall Gash

Inventor： Dinah W. Y. Sah ,  Andrei P. Guzaev ,  Matthew H. Adams ,  Pei Ge ,  Muthiah Manoharan ,  Douglas Ulen Gwost ,  Gregory Robert Stewart ,  David Kent Stiles ,  Brian Dale Nelson ,  William Frederick Kaemmerer ,  Don Marshall Gash

IPC: A61M5/168 ,  A61K49/00 ,  A61M5/142 ,  A61K31/7088

CPC classification number: A61K51/0491 ,  A61K49/04 ,  A61K49/06 ,  A61M5/007 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/321 ,  C12N2310/346 ,  C12N2310/3517 ,  C12N2320/10 ,  C12N2320/35 ,  C12N2310/3521

Abstract: This invention provides treatment compositions as well as systems and methods of determining and administering an effective amount of treatment for a neurological disorder. The treatment composition can contain a labeled interfering RNA (iRNA) agent capable of decreasing expression of a target RNA associated with the neurological disorder. The methods of the invention include determining an effective amount of a therapeutic composition by introducing a solution containing a tracer into the brain of a mammal. The tracing solution is monitored until a target volume of distribution at steady state distribution is substantially achieved, and the rate of delivery of the therapeutic composition is determined. The therapeutic composition can then be administered at the rate determined by use of the tracing solution.

Abstract translation: 本发明提供治疗组合物以及确定和施用有效量的神经障碍治疗的系统和方法。 治疗组合物可以含有能够降低与神经障碍相关的靶RNA表达的标记的干扰RNA（iRNA）试剂。 本发明的方法包括通过将含有示踪剂的溶液引入哺乳动物的脑中来确定治疗组合物的有效量。 监测追踪溶液，直到基本上达到稳定状态分布的目标体积分布，并确定治疗组合物的递送速率。 然后可以以通过使用追踪溶液确定的速率施用治疗组合物。