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公开(公告)号：US20220233693A1
公开(公告)日：2022-07-28
申请号：US17562961
申请日：2021-12-27
发明人： Masano HUANG , Thomas Arthur HABY , Mehrnaz KHOSSRAVI , Scott Aaron HART , Rao Venkatramana MANTRI , Heather Elizabeth VEZINA , Amit ROY , Bindu Purnima MURTHY , Urvi Ashish ARAS , Kinjal SANGHAVI , Xiaochen ZHAO , Akintunde BELLO
IPC分类号： A61K39/395 , C07K16/28 , A61K47/20 , A61K47/18 , A61K38/47 , A61K47/26 , A61K47/22 , A61K9/00
摘要： The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.
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公开(公告)号：US20240024471A1
公开(公告)日：2024-01-25
申请号：US18453265
申请日：2023-08-21
发明人： Masano HUANG , Thomas Arthur HABY , Mehrnaz KHOSSRAVI , Scott Aaron HART , Rao Venkatramana MANTRI , Heather Elizabeth VEZINA , Amit ROY , Bindu Purnima MURTHY , Urvi Ashish ARAS , Kinjal SANGHAVI , Xiaochen ZHAO , Akintunde BELLO
IPC分类号： A61K39/395 , C07K16/28 , A61K38/47 , A61K47/22 , A61P35/00
CPC分类号： A61K39/39558 , C07K16/2818 , A61K38/47 , C12Y302/01035 , A61K47/22 , A61K39/39591 , A61P35/00 , C07K2317/76 , A61K2039/545
摘要： The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.
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公开(公告)号：US20220233689A1
公开(公告)日：2022-07-28
申请号：US17562958
申请日：2021-12-27
发明人： Masano Huang , Thomas Arthur Haby , Mehrnaz KHOSSRAVI , Scott Aaron HART , Rao Venkatramana MANTRI , Heather Elizabeth VEZINA , Amit ROY , Bindu Purnima MURTHY , Urvi Ashish ARAS , Kinjal SANGHAVI , Xiaochen ZHAO , Akintunde BELLO
摘要： The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.
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公开(公告)号：US20240252629A1
公开(公告)日：2024-08-01
申请号：US18423089
申请日：2024-01-25
发明人： Masano HUANG , Thomas Arthur HABY , Mehrnaz KHOSSRAVI , Scott Aaron HART , Rao Venkatramana MANTRI , Heather Elizabeth VEZINA , Amit ROY , Bindu Purnima MURTHY , Urvi Ashish ARAS , Kinjal SANGHAVI , Xiaochen ZHAO , Akintunde BELLO
CPC分类号： A61K39/3955 , A61K9/0019 , A61K38/47 , A61K47/183 , A61K47/22 , A61K47/26 , A61K2039/545
摘要： The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.
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公开(公告)号：US20240000934A1
公开(公告)日：2024-01-04
申请号：US18453258
申请日：2023-08-21
发明人： Masano HUANG , Thomas Arthur HABY , Mehrnaz KHOSSRAVI , Scott Aaron HART , Rao Venkatramana MANTRI , Heather Elizabeth VEZINA , Amit ROY , Bindu Purnima MURTHY , Urvi Ashish ARAS , Kinjal SANGHAVI , Xiaochen ZHAO , Akintunde BELLO
IPC分类号： A61K39/395 , A61K9/00 , A61K38/47 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/26 , C07K16/28
CPC分类号： A61K39/39591 , A61K9/0019 , A61K38/47 , A61K39/3955 , A61K47/183 , A61K47/20 , A61K47/22 , A61K47/26 , C07K16/2803 , C07K16/2818 , C07K16/2827 , C12Y302/01035 , A61K2039/505
摘要： The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.
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