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公开(公告)号：US20170044578A1
公开(公告)日：2017-02-16
申请号：US15335628
申请日：2016-10-27
发明人： Yougen Li , Jessica McElvain , Steven Cary Rothman
CPC分类号： C12P7/16 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N15/52 , C12Y101/01001 , C12Y101/01086 , C12Y102/01003 , C12Y401/01001 , Y02E50/10 , Y02P20/52
摘要： Polypeptides having ketol-acid reductoisomerase activity are provided. Also disclosed are recombinant host cells comprising isobutanol biosynthetic pathways employing such polypeptides. Methods for producing isobutanol employing host cells comprising the polypeptides having ketol-acid reductoisomerase activity are also disclosed.
摘要翻译： 提供了具有酮酸酸还原异构酶活性的多肽。 还公开了包含使用这种多肽的异丁醇生物合成途径的重组宿主细胞。 还公开了使用包含具有酮酸 - 酸还原异构酶活性的多肽的宿主细胞产生异丁醇的方法。
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公开(公告)号：US20160032255A1
公开(公告)日：2016-02-04
申请号：US14853108
申请日：2015-09-14
发明人： Sridhar Govindarajan , Yougen Li , Der-Ing Liao , Daniel P. O'Keefe , Jeremy Stephen Minshull , Steven Cary Rothman , Alexander Vincent Tobias
CPC分类号： C12N9/0006 , C12P7/16 , C12P7/42 , C12P7/44 , C12P13/02 , C12P13/06 , C12P13/08 , C12Y101/01086 , Y02E50/10 , Y02P20/52
摘要： Provided herein are polypeptides having ketol-acid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.
摘要翻译： 本文提供具有酮酸酸还原异构酶活性的多肽以及包含这些多肽的微生物宿主细胞。 本文提供的多肽可用于生物合成途径，包括但不限于异丁醇生物合成途径。
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公开(公告)号：US09169467B2
公开(公告)日：2015-10-27
申请号：US13891963
申请日：2013-05-10
发明人： Sridhar Govindarajan , Yougen Li , Der-Ing Liao , Daniel P. O'Keefe , Jeremy Stephen Minshull , Steven Cary Rothman , Alexander Vincent Tobias
CPC分类号： C12N9/0006 , C12P7/16 , C12P7/42 , C12P7/44 , C12P13/02 , C12P13/06 , C12P13/08 , C12Y101/01086 , Y02E50/10 , Y02P20/52
摘要： Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.
摘要翻译： 本文提供具有酮促辅助还原异构酶活性的多肽以及包含这种多肽的微生物宿主细胞。 本文提供的多肽可用于生物合成途径，包括但不限于异丁醇生物合成途径。
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公开(公告)号：US10174345B2
公开(公告)日：2019-01-08
申请号：US15335628
申请日：2016-10-27
发明人： Yougen Li , Jessica McElvain , Steven Cary Rothman
摘要： Polypeptides having ketol-acid reductoisomerase activity are provided. Also disclosed are recombinant host cells comprising isobutanol biosynthetic pathways employing such polypeptides. Methods for producing isobutanol employing host cells comprising the polypeptides having ketol-acid reductoisomerase activity are also disclosed.
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公开(公告)号：US09388392B2
公开(公告)日：2016-07-12
申请号：US14853108
申请日：2015-09-14
发明人： Sridhar Govindarajan , Yougen Li , Der-Ing Liao , Daniel P. O'Keefe , Jeremy Stephen Minshull , Steven Cary Rothman , Alexander Vincent Tobias
CPC分类号： C12N9/0006 , C12P7/16 , C12P7/42 , C12P7/44 , C12P13/02 , C12P13/06 , C12P13/08 , C12Y101/01086 , Y02E50/10 , Y02P20/52
摘要： Provided herein are polypeptides having ketol-acid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.
摘要翻译： 本文提供具有酮酸酸还原异构酶活性的多肽以及包含这些多肽的微生物宿主细胞。 本文提供的多肽可用于生物合成途径，包括但不限于异丁醇生物合成途径。
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公开(公告)号：US20140051133A1
公开(公告)日：2014-02-20
申请号：US13891963
申请日：2013-05-10
发明人： Sridhar Govindarajan , Yougen Li , Der-Ing Liao , Daniel P. O'Keefe , Jeremy Stephen Minshull , Steven Cary Rothman , Alexander Vincent Tobias
IPC分类号： C12N9/04
CPC分类号： C12N9/0006 , C12P7/16 , C12P7/42 , C12P7/44 , C12P13/02 , C12P13/06 , C12P13/08 , C12Y101/01086 , Y02E50/10 , Y02P20/52
摘要： Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways.
摘要翻译： 本文提供具有酮促辅助还原异构酶活性的多肽以及包含这种多肽的微生物宿主细胞。 本文提供的多肽可用于生物合成途径，包括但不限于异丁醇生物合成途径。
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