Topiramate Immunoassays
    4.
    发明申请
    Topiramate Immunoassays 审中-公开
    托吡酯免疫测定

    公开(公告)号:US20090093069A1

    公开(公告)日:2009-04-09

    申请号:US12135145

    申请日:2008-06-07

    摘要: Diacetonefructose derivatives have substituents at the hydroxyl-position. Diacetonefructose derivatives may include immunogenic moieties to prepare anti-diacetonefructose derivative antibodies, or antigenic moieties for immunodiagnostic assays. Also, the diacetonefructose derivatives can include signal generating moieties for detecting the presence or amount of the diacetonefructose derivative in a sample. Additionally, the diacetonefructose derivatives can be used in immunodiagnostic assays to compete with topiramate for binding with anti-diacetonefructose derivative antibodies. Also, methods, compositions and kits are disclosed directed at diacetonefructose derivatives, immunogens, signal generating moieties and immunoassays for topiramate.

    摘要翻译: 二丙酮果糖衍生物在羟基位置具有取代基。 二丙酮果糖衍生物可包括免疫原性部分以制备抗二丙酮果糖衍生物抗体或用于免疫诊断测定的抗原部分。 此外,双丙酮果糖衍生物可以包括用于检测样品中二丙酮果糖衍生物的存在或量的信号产生部分。 此外,双丙酮果糖衍生物可用于免疫诊断测定以与托吡酯竞争与抗二丙酮果糖衍生物抗体结合。 此外,公开了针对二丙酮果糖衍生物,免疫原,信号产生部分和托吡酯的免疫测定法的方法,组合物和试剂盒。