公开(公告)号：US20230050058A1

公开(公告)日：2023-02-16

申请号：US17886374

申请日：2022-08-11

Applicant: California Institute of Technology

Inventor： Alessio Tamborini ,  Morteza Gharib

IPC: A61B5/021 ,  A61B5/022

Abstract: Systems and methods are provided for a non-invasive high resolution pressure pulse waveform measurement system. The system may include a blood pressure cuff, an air pump to inflate the blood pressure cuff to specific pressure levels, high resolution pressure sensors configured to perform high sensitivity signal acquisition at a specified pressure level, high range pressure sensors configured to measure an absolute reference for the signal and to calibrate the signal, pneumatic tubing connecting the air pump and sensors with the cuff, and a hydrodynamic filter configured as an input to a reference port of the high resolution pressure sensor. The hydrodynamic filter may be configured to transmit only mean pressure by attenuating a selected frequency range of the signal.

公开(公告)号：US11839427B2

公开(公告)日：2023-12-12

申请号：US16846155

申请日：2020-04-10

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Morteza Gharib ,  Alexei Harvard ,  Alessio Tamborini ,  David Jeon

IPC: A61B3/00 ,  A61B3/10 ,  A61B3/107 ,  A61B3/14 ,  A61B3/12 ,  A61B3/16 ,  A61B5/00 ,  A61B5/0205

CPC classification number: A61B3/0025 ,  A61B3/1005 ,  A61B3/107 ,  A61B3/1241 ,  A61B3/14 ,  A61B3/165 ,  A61B5/0205 ,  A61B5/7278 ,  A61B5/7282 ,  A61B3/0041 ,  A61B5/0013

Abstract: Systems, methods and apparatuses are provided for the measurement of intraocular pressure. These systems, methods and apparatuses can include an imaging apparatus for capturing two- or three-dimensional images or video of a patient's eye. An image reconstruction based on the captured images or video can be performed, and measurements can be taken of blood vessel features, curvature metrics, or distances between point pairs. In some embodiments, blood pressure measurements can also be taken synchronously with the captured images or video. From these measurements, a relationship between certain medical condition (e.g., elevated intraocular pressure, heart arrhythmia) and the extracted metrics can be established.

公开(公告)号：US20200323427A1

公开(公告)日：2020-10-15

申请号：US16846155

申请日：2020-04-10

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Morteza Gharib ,  Alexei Harvard ,  Alessio Tamborini ,  David Jeon

IPC: A61B3/00 ,  A61B3/14 ,  A61B3/10 ,  A61B3/12 ,  A61B3/16 ,  A61B5/0205 ,  A61B3/107 ,  A61B5/00

Abstract: Systems, methods and apparatuses are provided for the measurement of intraocular pressure. These systems, methods and apparatuses can include an imaging apparatus for capturing two- or three-dimensional images or video of a patient's eye. An image reconstruction based on the captured images or video can be performed, and measurements can be taken of blood vessel features, curvature metrics, or distances between point pairs. In some embodiments, blood pressure measurements can also be taken synchronously with the captured images or video. From these measurements, a relationship between certain medical condition (e.g., elevated intraocular pressure, heart arrhythmia) and the extracted metrics can be established.