公开(公告)号：US20240319184A1

公开(公告)日：2024-09-26

申请号：US18277000

申请日：2022-02-11

Applicant: CAMBRIDGE ENTERPRISE LIMITED

Inventor： Tuomas Pertti Jonathan Knowles ,  Raphael Philippe Bernard Jacquat ,  Thomas Mueller ,  Quentin Peter

IPC: G01N33/561 ,  G01N13/00 ,  G01N33/543

CPC classification number: G01N33/561 ,  G01N13/00 ,  G01N33/54326 ,  G01N2013/003

Abstract: A method of determining diffusion coefficient of one or more components in a polydisperse sample is provided. The method comprising the steps of: introducing an auxiliary fluid flow into a fractionation channel; introducing the polydisperse sample comprising one or more components into the fractionation channel; allowing the sample and the auxiliary fluid to create a combined flow; fractionating the combined flow into two or more fractions by diffusive sizing; subsequently separating two or more components from each fraction by creating a distribution of the components within a separation channel; detecting a characteristic of each the two or more components in each fraction; and comparing the characteristic of each component in each fraction in order to determine the diffusion coefficient of each of the one or more components in the polydisperse sample.