公开(公告)号：US10104881B2

公开(公告)日：2018-10-23

申请号：US14431621

申请日：2012-09-27

Applicant: CEFO Co., Ltd.

Inventor： Sunray Lee ,  Jin Yup Lee ,  Hyun Jung Mo ,  Hyun-Sook Park

IPC: A01N1/02 ,  C12N5/07 ,  C12N5/0735

Abstract: The present invention relates to a composition including plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells, and use thereof, more particularly, to a composition including plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells, in which the albumin, lipids, and plant protein hydrolysates are present in sufficient quantities to reduce cell death caused by freezing while maintaining animal-free and xeno-free conditions during long-term preservation of stem cells or primary cells; and to a method for cryopreservation of stem cells or primary cells using the composition.

公开(公告)号：US20150327537A1

公开(公告)日：2015-11-19

申请号：US14431621

申请日：2012-09-27

Applicant: CEFO CO., LTD.

Inventor： Sunray Lee ,  Jin Yup Lee ,  Hyun Jung Mo ,  Hyun-Sook Park

IPC: A01N1/02

CPC classification number: A01N1/0221 ,  A01N1/0284 ,  C12N5/06 ,  C12N5/0606

Abstract: The present invention relates to a composition including plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells, and use thereof, more particularly, to a composition including plant-derived recombinant human serum albumin, lipids, and plant protein hydrolysates as active ingredients for cryopreservation of stem cells or primary cells, in which the albumin, lipids, and plant protein hydrolysates are present in sufficient quantities to reduce cell death caused by freezing while maintaining animal-free and xeno-free conditions during long-term preservation of stem cells or primary cells; and to a method for cryopreservation of stem cells or primary cells using the composition.

Abstract translation: 本发明涉及一种包含植物来源的重组人血清白蛋白，脂质和植物蛋白水解物作为干细胞或原代细胞的低温保存活性成分的组合物，更具体地涉及包含植物来源的重组人 血清白蛋白，脂质和植物蛋白水解物作为干细胞或原代细胞的低温保存的活性成分，其中白蛋白，脂质和植物蛋白水解物以足够的量存在，以减少冻结引起的细胞死亡，同时保持无动物和 在干细胞或原代细胞的长期保存期间不含异种病毒的条件; 以及使用该组合物冷冻保存干细胞或原代细胞的方法。

公开(公告)号：US11345887B2

公开(公告)日：2022-05-31

申请号：US15502699

申请日：2015-08-06

Applicant: CEFO CO., LTD

Inventor： Hyun Sook Park ,  Sun Ray Lee ,  Jin Yup Lee ,  Hyun Jung Mo

IPC: A01N1/02 ,  C12N5/02 ,  C12N5/0735 ,  C12N5/0797 ,  C12N5/0775 ,  C12N5/071 ,  C12N5/074

Abstract: The present invention relates to a composition for preserving cells and a method for preserving cells and, more specifically, to: a composition for preserving cells, containing, as active ingredients, plant-derived recombinant human serum albumin and plant peptides, wherein the composition maintains a high cellular survival rate while maintaining animal-free and xeno-free properties and is stable without changes in cellular morphology or surface expression factors in the short-term preservation of cells such as stem cells or primary cultured cells; and a method for preserving cells by using the same.