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公开(公告)号：US20190127410A1
公开(公告)日：2019-05-02
申请号：US16231960
申请日：2018-12-25
发明人： HOULEI TENG , Wei Wu
IPC分类号： C07H7/06 , C07H1/06 , C07D455/03
摘要： The present invention provides a mangiferin-6-O-calcium salt and a preparation process thereof. In addition, use of the mangiferin-6-O-calcium salt as defined in claim 1 as an intermediate in the preparation of a mangiferin-6-O-berberine salt is also provided.
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公开(公告)号：US10538547B2
公开(公告)日：2020-01-21
申请号：US16231960
申请日：2018-12-25
发明人： Houlei Teng , Wei Wu
IPC分类号： C07H1/00 , C07H1/06 , C07H7/04 , C07H7/06 , C07D455/03
摘要： The present invention provides a mangiferin-6-O-calcium salt and a preparation process thereof. In addition, use of the mangiferin-6-O-calcium salt as defined in claim 1 as an intermediate in the preparation of a mangiferin-6-O-berberine salt is also provided.
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公开(公告)号：US10285969B2
公开(公告)日：2019-05-14
申请号：US15619936
申请日：2017-06-12
发明人： Houlei Teng , Wei Wu , Jingzhuo Zhang , Zhe Lin
IPC分类号： C07D407/02 , C07D407/04 , C07D455/03 , A61K31/352 , A61K31/4375 , A61K9/00 , A61K9/20 , C07D455/04 , A61K9/06 , A61K9/16 , A61K9/19 , A61K9/48 , A61P3/00
摘要： The present invention provides a mangiferin-6-O-berberine salt and a preparation method thereof, and further provides a use of the mangiferin-6-O-berberine salt for the treatment of diabetics and other diseases as an AMPK activator.
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公开(公告)号：US20170273940A1
公开(公告)日：2017-09-28
申请号：US15619936
申请日：2017-06-12
发明人： Houlei TENG , Wei Wu , Jingzhuo Zhang , Zhe Lin
IPC分类号： A61K31/352 , A61K9/20 , C07D407/04 , A61K9/00 , A61K31/4375 , C07D455/04
CPC分类号： A61K31/352 , A61K9/0095 , A61K9/06 , A61K9/1635 , A61K9/1652 , A61K9/19 , A61K9/20 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/4866 , A61K31/4375 , A61P3/00 , C07D407/04 , C07D455/03 , C07D455/04
摘要： The present invention provides a mangiferin-6-O-berberine salt and a preparation method thereof, and further provides a use of the mangiferin-6-O-berberine salt for the treatment of diabetics and other diseases as an AMPK activator.
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