公开(公告)号：US20230040524A1

公开(公告)日：2023-02-09

申请号：US17779909

申请日：2020-08-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Chan Hong AHN ,  Ju Eun KIM ,  Hyun-jung BAE ,  Imsang LEE ,  Ji Hye LEE ,  Hayun LEE

IPC: C12N9/10 ,  C12N15/77 ,  C12P13/06

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase, a microorganism producing leucine comprising the modified polypeptide, and a method for producing an L-amino acid using the microorganism.

公开(公告)号：US20240384253A1

公开(公告)日：2024-11-21

申请号：US18275163

申请日：2022-01-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hayun LEE ,  Ju Eun KIM ,  Ji Hye LEE ,  Kyungrim KIM ,  Heeseok LEE

IPC: C12N9/88 ,  C12P13/06 ,  C12P13/08

Abstract: Provided is a prephenate dehydratase variant.

公开(公告)号：US20240093252A1

公开(公告)日：2024-03-21

申请号：US18274912

申请日：2022-01-28

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hayun LEE ,  Ju Eun KIM ,  Ji Hye LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/77

CPC classification number: C12P13/06 ,  C12N9/1025 ,  C12N15/77 ,  C12R2001/15 ,  C12Y203/03013

Abstract: The present disclosure relates to an isopropylmalate synthase variant and a method of producing L-leucine using the same.

公开(公告)号：US20240093163A1

公开(公告)日：2024-03-21

申请号：US18274196

申请日：2021-11-18

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hayun LEE ,  Ju Eun KIM ,  Ji Hye LEE ,  Heeseok LEE ,  Kyungrim KIM

IPC: C12N9/10 ,  C12P13/06 ,  C12P13/08

CPC classification number: C12N9/1085 ,  C12P13/06 ,  C12P13/08 ,  C12Y205/01054

Abstract: The present application relates to an aroG aldolase (phospho-2-dehydro-3-deoxyheptonate aldolase) variant, a microorganism comprising the same, and a method for producing amino acids using the same.

公开(公告)号：US20230088135A1

公开(公告)日：2023-03-23

申请号：US17760462

申请日：2021-05-13

Applicant: CJ CheilJedang Corporation

Inventor： Hayun LEE ,  Ju Eun KIM ,  Jihyun SHIM ,  Ji Hye LEE ,  Sung Gun LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/77

Abstract: The present application relates to: a novel mutant polypeptide having isopropylmalate synthase activity; and a method for producing L-leucine by using same. L-leucine can be produced at high yield by using the mutant polypeptide according to an embodiment.