公开(公告)号：US10208325B2

公开(公告)日：2019-02-19

申请号：US15309387

申请日：2015-05-08

Applicant: CJ Cheiljedang Corporation

Inventor： Peter Lee ,  Jun Ok Moon ,  Hyung Joon Kim ,  Song Gi Ryu

IPC: C12P13/08 ,  C07K14/34 ,  C12N9/16 ,  C12R1/15

Abstract: Provided are a microorganism of the genus Corynebacterium having an enhanced activity to produce L-lysine as a result of inactivating a secretory protein and a method for producing L-lysine using the microorganism.

公开(公告)号：US11104925B2

公开(公告)日：2021-08-31

申请号：US15741392

申请日：2016-06-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Peter Lee ,  Hyung Joon Kim ,  Hyang Choi ,  Song Gi Ryu ,  Sang Mok Lee

IPC: C12P13/08 ,  C12N15/77 ,  C07K14/34

Abstract: The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus Corynebacterium, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

公开(公告)号：US20180195097A1

公开(公告)日：2018-07-12

申请号：US15741392

申请日：2016-06-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Peter Lee ,  Hyung Joon Kim ,  Hyang Choi ,  Song Gi Ryu ,  Sang Mok Lee

IPC: C12P13/08 ,  C07K14/34 ,  C12N15/77

CPC classification number: C12P13/08 ,  C07K14/34 ,  C12N15/77

Abstract: The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus Corynebacterium, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

公开(公告)号：US20200224228A1

公开(公告)日：2020-07-16

申请号：US16627572

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to an O-succinyl homoserine transferase mutant, a polynucleotide encoding the same, a microorganism including the mutant, and a method of producing O-succinyl homoserine using the microorganism.

公开(公告)号：US10982245B2

公开(公告)日：2021-04-20

申请号：US16627572

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12P13/06 ,  C12P13/12 ,  C12R1/15

Abstract: The present disclosure relates to an O-succinyl homoserine transferase mutant, a polynucleotide encoding the same, a microorganism including the mutant, and a method of producing O-succinyl homoserine using the microorganism.

公开(公告)号：US20200332322A1

公开(公告)日：2020-10-22

申请号：US16627655

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12P13/06 ,  C12P13/12 ,  C12N9/12

Abstract: Provided are an O-succinyl homoserine transferase variant, a polynucleotide encoding the variant, a microorganism comprising the variant, and a method of producing O-succinyl homoserine using the microorganism.

公开(公告)号：US11142779B2

公开(公告)日：2021-10-12

申请号：US16627655

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12N9/10 ,  C12N1/21 ,  C12P13/06 ,  C12P13/12 ,  C12N9/12

Abstract: Provided are an O-succinyl homoserine transferase variant, a polynucleotide encoding the variant, a microorganism comprising the variant, and a method of producing O-succinyl homoserine using the microorganism.