公开(公告)号：US3901921A

公开(公告)日：1975-08-26

申请号：US24734272

申请日：1972-04-25

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： URRY WILBERT HERBERT ,  MULLENBACH GUY TOWNS

IPC: C07C45/00 ,  C07C45/51 ,  C07C57/03 ,  C07C309/73 ,  C07D313/00 ,  C07D321/00 ,  C07D7/26 ,  C07D9/00

CPC classification number: C07D321/00 ,  C07C45/004 ,  C07C45/512 ,  C07C45/515 ,  C07C57/03 ,  C07C309/73 ,  C07C403/02 ,  C07C2601/16 ,  C07D313/00 ,  C07C47/21

Abstract: Compounds of the formula

where X is an integer from 0 to 12, are synthesized employing a process involving lactone ring closure of compounds of the formula

D R A W I N G

公开(公告)号：US3901922A

公开(公告)日：1975-08-26

申请号：US45540974

申请日：1974-03-27

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： URRY WILBERT HERBERT ,  MULLENBACH GUY TOWNS

IPC: C07C47/21 ,  C07C51/353 ,  C07D9/00

CPC classification number: C07C45/512 ,  C07C47/21 ,  C07C51/353 ,  C07C403/02 ,  C07C2601/16 ,  C07C57/03

Abstract: WHEREIN X is an integer having a value from 2 to 6 inclusive and Y is an integer having a value from 2 to 8 inclusive. It also provides for new methods of making compounds useful in the synthesis of zearalanone and related compounds. The new compounds useful as intermediates are 2,7-octadienoic acid; methyl 2,7-octadienoate; sodium ethyl 6-(4-pentenyl)- Beta -dihydroesorcylate; ethyl 6-(4-pentenyl)- Beta dihydroresorcylate; sodium methyl 6-(4-pentenyl)- Beta dihydroresorcylate; methyl 6-(4-pentenyl)- Beta dihydroresorcylate; methyl 3-bromo-6-(4-pentenyl)- Beta dihydroresorcylate; methyl 6-(4-pentenyl)- Beta -resorcylate; ethyl 6-(4-pentenyl)- Beta -resorcylate; ethyl 6-(4-pentenyl)Beta -resorcylate dibenzyl ether; tetrahydropyran-2-yl 4-penten2-yl ether; ethyl 6-(6-oxo-10-tetrahydropyran-2-xyloxyundecyl)Beta -resorcylate dibenzyl ether; and 6-(10-hydroxy-6oxounderyl)- Beta -resorcylic acid dibenzyl ether. Methods for preparing these intermediates are also disclosed.
This invention provides a new synthesis for zearalanone and for related compounds having more or fewer carbon atoms in the nonaromatic ring than does zearalanone, which related compounds and zearalanone are represented by the formula

公开(公告)号：US3862980A

公开(公告)日：1975-01-28

申请号：US24741472

申请日：1972-04-25

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： URRY WILBERT HERBERT ,  MULLENBACH GUY TOWNS

IPC: C07C51/38 ,  C07C69/92 ,  C07D313/00 ,  C07C69/78

CPC classification number: C07C403/02 ,  C07C45/512 ,  C07C51/38 ,  C07C67/00 ,  C07C67/03 ,  C07C67/307 ,  C07C67/31 ,  C07C69/92 ,  C07C2601/16 ,  C07D313/00 ,  C07C47/21 ,  C07C57/03 ,  C07C69/587 ,  C07C69/738 ,  C07C69/73

Abstract: 4-Penten-2-yl 6-(4-pentenyl)- Beta -resorcylate dibenzyl ether useful in preparing zearalone is disclosed. Zearalone is useful in promoting the growth rate of meat producing animals.

Abstract translation: 公开了可用于制备zearalone的4-戊烯-2-基6-（4-戊烯基）-β-间苯二甲酸二苄基醚。 Zearalone有助于促进肉类生产动物的生长速度。