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公开(公告)号:US20140005056A1
公开(公告)日:2014-01-02
申请号:US14028319
申请日:2013-09-16
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev , Peter Hong
IPC: C12Q1/68
CPC classification number: B01J19/0046 , B01J2219/00722 , C12P19/34 , C12Q1/6869 , C12Q1/6874 , C12Q2525/101 , C12Q2521/101
Abstract: The present invention is directed to methods and compositions for long fragment read sequencing. The present invention encompasses methods and compositions for preparing long fragments of genomic DNA, for processing genomic DNA for long fragment read sequencing methods, as well as software and algorithms for processing and analyzing sequence data.
Abstract translation: 本发明涉及用于长片段读取测序的方法和组合物。 本发明包括用于制备基因组DNA长片段的方法和组合物,用于处理长片段读取测序方法的基因组DNA,以及用于处理和分析序列数据的软件和算法。
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公开(公告)号:US20190002970A1
公开(公告)日:2019-01-03
申请号:US15993418
申请日:2018-05-30
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/6869
Abstract: This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
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公开(公告)号:US20160046985A1
公开(公告)日:2016-02-18
申请号:US14782307
申请日:2014-03-17
Applicant: COMPLETE GENOMICS, INC.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/68
Abstract: The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
Abstract translation: 本发明提供了用于标记靶核酸的长片段的方法和组合物,用于测序和分析所得到的序列信息,以便例如减少错误并进行单倍型定相。
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公开(公告)号:US20220362735A1
公开(公告)日:2022-11-17
申请号:US17840843
申请日:2022-06-15
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev , Peter Hong
IPC: B01J19/00 , C12P19/34 , C12Q1/6869 , C12N15/10 , C12Q1/6874
Abstract: This disclosure provides methods and compositions for long fragment read sequencing. Technology is described for preparing long fragments of genomic DNA, for processing genomic DNA for long fragment read sequencing methods, as well as software and algorithms for processing and analyzing sequence data. Combinatorial oligonucleotide bar codes are used to label fragments from nearby portions of the genome, which facilitate computational assembly of sequence reads to obtain the genome sequence. This improves efficiency and accuracy of sequencing, whereby an entire sequence can be obtained from fragments that constitute a lower coverage amount of the genome.
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公开(公告)号:US10557166B2
公开(公告)日:2020-02-11
申请号:US14782307
申请日:2014-03-17
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C40B20/00 , C40B50/06 , C12Q1/68 , C07H21/02 , C12Q1/6869 , C12Q1/6806 , C12N15/10
Abstract: The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
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公开(公告)号:US20190002969A1
公开(公告)日:2019-01-03
申请号:US15936123
申请日:2018-03-26
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/6869
Abstract: The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
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公开(公告)号:US12071659B2
公开(公告)日:2024-08-27
申请号:US15936123
申请日:2018-03-26
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/6869 , C12N15/10 , C12Q1/6806
CPC classification number: C12Q1/6869 , C12Q1/6806 , C12N15/1065 , C12Q2525/204 , C12Q1/6806 , C12Q2525/301 , C12Q2535/122 , C12Q2563/179 , C12Q1/6869 , C12Q2525/301 , C12Q2535/122 , C12Q2563/179 , C12Q1/6869 , C12Q2521/507
Abstract: The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
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公开(公告)号:US20180355421A9
公开(公告)日:2018-12-13
申请号:US14782307
申请日:2014-03-17
Applicant: COMPLETE GENOMICS, INC.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/68
Abstract: The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
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公开(公告)号:US20170022554A1
公开(公告)日:2017-01-26
申请号:US15136780
申请日:2016-04-22
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
IPC: C12Q1/68
CPC classification number: C12Q1/6869 , C12N15/1065 , C12Q1/6806 , C12Q2525/204 , C12Q2525/301 , C12Q2535/122 , C12Q2563/179 , C12Q2521/507
Abstract: This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
Abstract translation: 本公开提供了用于标记靶核酸的长片段的方法和组合物,用于测序和分析所得到的序列信息,以便例如减少错误并进行单倍型定相。
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公开(公告)号:US09328382B2
公开(公告)日:2016-05-03
申请号:US14205145
申请日:2014-03-11
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Brock A. Peters , Andrei Alexeev
CPC classification number: C12Q1/6869 , C12N15/1065 , C12Q1/6806 , C12Q2525/204 , C12Q2525/301 , C12Q2535/122 , C12Q2563/179 , C12Q2521/507
Abstract: This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.
Abstract translation: 本公开提供了用于标记靶核酸的长片段的方法和组合物,用于测序和分析所得到的序列信息,以便例如减少错误并进行单倍型定相。
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